Endovascular treatmenT for Acute Ischemic Stroke in China (DETECT2-China)
enDovascular trEatmenT for acutE isChemic sTroke in China (DETECT2-China): a Prospective, National, Multi-center, Registry Study
1 other identifier
observational
3,000
1 country
1
Brief Summary
This is a prospective real world registry study, aiming to explore the effectiveness and safety of endovascular treatment of acute ischemic stroke in a Chinese population.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2022
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 13, 2021
CompletedFirst Posted
Study publicly available on registry
October 25, 2021
CompletedStudy Start
First participant enrolled
January 21, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 10, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
January 10, 2025
CompletedMarch 18, 2025
March 1, 2025
3 years
October 13, 2021
March 14, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Proportion of patients with modified Rankin Score 0 to 2
the minimum and maximum values of modified Rankin Score are 0 and 6, respectively; higher score mean a worse outcome
Day 90
Secondary Outcomes (5)
Proportion of patients with modified Rankin Score 0 to 1
Day 90
Distribution of modified Rankin Score
Day 90
Changes in National Institute of Health stroke scale (NIHSS)
24 hours, 48 hours, and 2 weeks
Proportion of symptomatic intracranial hemorrhage (sICH)
48 hours
Proportion of death
7 days
Other Outcomes (4)
neuroimaging associated with clinical outcome
48 hours
changes in serum biomarkers
48 hours
dynamic changes of TCD data associated
24 hours
- +1 more other outcomes
Interventions
all enrolled patients must receive endovascular treatment
Eligibility Criteria
acute ischemic stroke with large vessel oclussion
You may qualify if:
- Age: ≥ 18;
- Ischemic stroke confirmed by head CT or MRI;
- Patients receiving endovascular treatment;
- First ever stroke or pre-stroke mRS≤2;
- signed informed consent.
You may not qualify if:
- Prestroke mRS≥3;
- Other serious illness that would confound the clinical outcome at 90 days;
- Unavailable neuroimaging data;
- Other unsuitable conditions judged by the investigator
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hui-Sheng Chen
Shenyang, Liaoning, 110840, China
Related Publications (1)
Liu L, Nguyen TN, Chen HS. Endovascular Treatment for Acute Ischemic Stroke in China: a study protocol for a prospective, national, multi-center, registry study. Front Neurol. 2023 Aug 10;14:1171718. doi: 10.3389/fneur.2023.1171718. eCollection 2023.
PMID: 37638196DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 3 Months
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Head of Neurology
Study Record Dates
First Submitted
October 13, 2021
First Posted
October 25, 2021
Study Start
January 21, 2022
Primary Completion
January 10, 2025
Study Completion
January 10, 2025
Last Updated
March 18, 2025
Record last verified: 2025-03