NCT05213754

Brief Summary

The Acute Ischemic Stroke Registry for Endovascular Treatment (AIS-EVT) is an academic, prospective, multicenter, observational registry study. Consecutive stroke patients treated with endovascular treatment will be enrolled in stroke centers. Baseline information and clinical follow-up information at 90 days of stroke onset are collected. Data collected include demographics, comorbidities, pathogenesis, blood pressures, stroke severity on admission, time intervals, reperfusion condition, and functional outcome, et al.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2021

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2021

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

January 17, 2022

Completed
11 days until next milestone

First Posted

Study publicly available on registry

January 28, 2022

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2022

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2023

Completed
Last Updated

January 28, 2022

Status Verified

January 1, 2022

Enrollment Period

1.9 years

First QC Date

January 17, 2022

Last Update Submit

January 17, 2022

Conditions

Acute Ischemic Stroke

Keywords

Acute ischemic strokeEndovascular treatmentOutcomeRegistry

Outcome Measures

Primary Outcomes (1)

  • The modified Rankin Scale score at 90 days

    The range of the modified Rankin Scale is from 0 to 6. A higher score indicates a worse outcome. 0-No symptoms; 1-No significant disability; 2-Slight disability; 3-Moderate disability; 4-Moderately severe disability; 5-Severe disability; 6-Dead.

    90 days

Interventions

Endovascular TreatmentPROCEDURE

Re-open the occluded cerebral artery using endovascular treatment

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Acute ischemic stroke patients with large vessel occlusion receiving endovascular treatment.

You may qualify if:

  • Diagnosis of acute ischemic stroke;
  • Imaging confirmed intracranial large vessel occlusion: intracranial internal carotid artery (ICA), middle cerebral artery (MCA M1/M2), anterior cerebral artery (ACA A1/A2), basilar artery (BA), vertebral artery (VA V4), and posterior cerebral artery (PCA P1);
  • Initiation of any type of endovascular treatment, including intra-arterial thrombolysis, mechanical thrombectomy, aspiration, angioplasty, and stenting;
  • Verbal and written informed consent was provided at the time of admission by patients or their legal authorized representatives.

You may not qualify if:

  • No evidence of large vessel occlusion on digital subtraction angiography.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Xuanwu Hospital, Capital Medical University

Beijing, Beijing Municipality, 100053, China

RECRUITING

MeSH Terms

Conditions

Ischemic Stroke

Condition Hierarchy (Ancestors)

StrokeCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Central Study Contacts

Xunming Ji, MD

CONTACT

010-83198952jixm@ccmu.edu.cn

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
90 Days
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

January 17, 2022

First Posted

January 28, 2022

Study Start

January 1, 2021

Primary Completion

December 1, 2022

Study Completion

June 1, 2023

Last Updated

January 28, 2022

Record last verified: 2022-01

Locations

CN(1)