Magnesium Injection Ensures Steroid Avoidance During Vaccine, Viremia or Immunocompromise

NCT05862454 | Recruiting

• 1 other identifier: SalemAnes2022 Mg Steroid Avoid
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

Steroid injections are used for interventional pain management. However, their side-effect of immunosuppression may increase the risk of infections. Magnesium is an alternative anti-nociceptive injection that may be used instead of steroids. Prospective observational study of patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant.

Conditions

Steroid Metabolism Disorder

Keywords

Magnesium; Steroid avoidance

Outcome Measures

Primary Outcomes (1)

• Pain score, objective measurement using the validated Numeric Pain Rating scale

  Pain score, using the Numeric Pain Rating scale of 0 to 10, low scores indicate less pain, high scores indicate worse pain

  12 weeks

Secondary Outcomes (1)

• Sleep quality score, objective measurement using the validated Likert sleep scale

  12 weeks

Study Arms (1)

Adult chronic pain patients

Cohort of adult chronic pain patients, undergoing interventional injection therapy for pain management at a Canadian pain clinic

Drug: Magnesium

Interventions

Magnesium DRUG

Magnesium injection therapy

Also known as: Magnesium injection

Adult chronic pain patients

Eligibility Criteria

• Age: 20 Years - 99 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Cohort of consecutive adult patients, undergoing interventional injection therapy for pain management at a Canadian pain clinic

You may qualify if:

• adult chronic pain patients
• previous interventional injection therapy
• consent for interventional injection therapy
• good treatment compliance
• regular sleep diary
• regular pain diary
• informed consent for diary review
• consent for clinical record quality assurance review

You may not qualify if:

• organ insufficiency
• cognitive disorder
• inability to provide consent
• major neuropsychiatric disorder
• unreliable diary
• poor treatment compliance
• previous adverse/allergic reactions to magnesium

Sponsors & Collaborators

• Salem Anaesthesia Pain Clinic: lead

Study Sites (1)

Salem Anaesthesia Pain Clinic

Surrey, British Columbia, V3S 7J1, Canada

RECRUITING

MeSH Terms

Interventions

Magnesium

Intervention Hierarchy (Ancestors)

Metals, Alkaline Earth; Elements; Inorganic Chemicals; Metals, Light; Metals

Study Officials

• Olu Bamgbade, MD,FRCPC

  Salem Anaesthesia Pain Clinic

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Olu Bamgbade, MD,FRCPC

CONTACT

17786286600; salem.painclinic@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 7, 2023
• First Posted: May 17, 2023
• Study Start: July 2, 2020
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: January 27, 2025

Record last verified: 2025-01

Locations

CA (1)