NCT05861414

Brief Summary

Objective: To investigate the effects of emotional working memory training (EWM-T) on depressive symptoms and rumination among university students. Methods: The experimental group comprised 25 participants who underwent 21 days of emotional working memory training, which involved viewing a continuous stream of negative emotional face content on a grid and remembering the faces and locations presented on the grid. The control group consisted of 25 participants. The Beck Depression Inventory-II (BDI-II), the Chinese version of the Character-Digital Breadth Test, and the Ruminative Responses Scale (RRS) were used as the pre- and post-test indicators.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 11, 2022

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 11, 2022

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 21, 2023

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

April 26, 2023

Completed
20 days until next milestone

First Posted

Study publicly available on registry

May 16, 2023

Completed
Last Updated

May 16, 2023

Status Verified

May 1, 2023

Enrollment Period

1 month

First QC Date

April 26, 2023

Last Update Submit

May 15, 2023

Conditions

Keywords

Emotional working memory trainingDepressive symptoms

Outcome Measures

Primary Outcomes (3)

  • Beck Depression Inventory-II (BDI-II) score

    Beck Depression Inventory-Ⅱ is the most prevalent self-report scale assessing the presence and severity of depressive symptoms. It is a 21-item scale that was used to assess the severity of depressive symptoms in the past two weeks. The scores range from 0 to 63. A higher total score on the scale indicated more severe depressive symptoms.

    one month

  • Ruminative Responses Scale (RRS) score

    The Ruminative Response Scale (RRS) is a scale of 22 items scored on a 4-point Likert scale ranging from 1 (almost never) to 4 (almost always). It was used to assess ruminative thinking, with higher scores indicating a higher degree of ruminative symptoms. It includes three dimensions: symptom rumination, forced thinking, and introspective.

    one month

  • The Chinese version of the Character-Digital Breadth Test score

    The experimenter read aloud some combinations of characters and numbers, and after the experimenter finished speaking, the participants first stated the numbers in descending order and then the characters in descending order. For example, in the fourth pass: "8B3A," the participant needed to answer "38AB," and then the test began after the person understood the rules. Different levels (2-9 levels) had various lengths of characters and numbers. The higher the level, the longer the length. Each level contained four items. Scoring was based on the total number of correct items passed (correct number of character digit spans) and the rank of the longest items passed (longest sequence of character digit spans). Each item was completed when all items at a certain level were incorrect. The greater the number of correct items passed, the higher the level of the longest items, the greater the working memory breadth, and the stronger the working memory ability .

    one month

Study Arms (2)

Experimental group

EXPERIMENTAL

21 days of emotional working memory training

Behavioral: EWM-T

control group

NO INTERVENTION

Interventions

EWM-TBEHAVIORAL

This paradigm was adapted from the n-back program described by Jaeggi et al. (2009) and comprised an affective dual n-back task consisting of a series of trials, each of which simultaneously presented a face (for 500 ms) on a 4 × 4 grid on a monitor. Intermediate interval 2500ms, during which, Participants press a button to determine if the current face or position is consistent with the first n. If the position is the same, press "F"; if the face is the same, press "J"; if the face and position are not the same, do not react. The faces used in this training were selected from the Chinese Facial Emotional Picture System (CFAPS), and 12 faces (six male and six female) with fear, anger, disgust, and sadness were selected as n-back experimental materials.

Experimental group

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Study from Fujian Medical University, BDI-II scores above 14 points.

You may not qualify if:

  • no suicidal behavior

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Health, Fujian Medical University

Fuzhou, China

Location

MeSH Terms

Conditions

Depression

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Master

Study Record Dates

First Submitted

April 26, 2023

First Posted

May 16, 2023

Study Start

October 11, 2022

Primary Completion

November 11, 2022

Study Completion

March 21, 2023

Last Updated

May 16, 2023

Record last verified: 2023-05

Locations