NCT05849376

Brief Summary

The goals of this project are to (a) incorporate empirical findings on imitation training and learning in autistic children into a comprehensive protocol for Applied Behavior Analysis practitioners designed to rapidly facilitate generalized imitation called Emergent Multi-Class Imitation Training (EMIT), and (b) collect pilot data on the efficacy of EMIT with a small sample of autistic children. EMIT will incorporate several features that are grounded in prior research including: (a) evidence-based procedures for establishing trained matching relations (a pre-requisite to generalized imitation), (b) concurrent training of different response types (e.g., motor imitation, object imitation, vocal imitation) to address restricted generalization, (c) multiple manipulative object imitation training, (d) evidence-based procedures for remediating slow acquisition, and (e) frequent tests for the emergence of generalized imitation. EMIT will be the first protocol designed for clinical use that reflects research findings on imitation learning spanning almost five decades.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for not_applicable

Timeline
15mo left

Started Mar 2022

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress77%
Mar 2022Aug 2027

Study Start

First participant enrolled

March 27, 2022

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

April 5, 2023

Completed
1 month until next milestone

First Posted

Study publicly available on registry

May 8, 2023

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2027

Last Updated

May 19, 2026

Status Verified

July 1, 2025

Enrollment Period

5.4 years

First QC Date

April 5, 2023

Last Update Submit

May 15, 2026

Conditions

Keywords

AutismImitation

Outcome Measures

Primary Outcomes (1)

  • Probe performance

    Correct responding to probe trials (novel targets)

    Approximately 3x per week throughout participant's EMIT intervention, approximately 3-6 months

Secondary Outcomes (1)

  • Motor Vocal Imitation Assessment

    Pre-Intervention and Post-Intervention (within 2 weeks of intervention completion)

Study Arms (1)

EMIT Intervention

EXPERIMENTAL

Participants will receive the EMIT intervention.

Behavioral: Emergent Multi-Class Imitation Training

Interventions

Sessions will be conducted in a room with minimal distractions containing a table, two chairs, a timer, and 3-4 highly preferred (HP) items identified by preference assessments. A maximum of 10 sessions per week will be distributed across at least 3 days per week. Each session will take 15-20 min to conduct. Novel probe trials will be embedded throughout all sessions to continuously assess for the emergence of generalized imitation. When participants can consistently imitate novel probe responses, the intervention will conclude.

EMIT Intervention

Eligibility Criteria

Age12 Months - 6 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Diagnosis of autism spectrum disorder
  • Age 5 or under
  • Maximum score of 40 on Motor Vocal Imitation Assessment
  • Demonstrates identity matching above chance levels

You may not qualify if:

  • Diagnosis of intellectual disability
  • Diagnosis of certain conditions that impact motor function (e.g., cerebral palsy)
  • Visual impairment
  • Hearing impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rutgers University

New Brunswick, New Jersey, 08901, United States

RECRUITING

MeSH Terms

Conditions

Autism Spectrum DisorderAutistic Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, PervasiveNeurodevelopmental DisordersMental Disorders

Study Officials

  • Meghan A Deshais, Ph.D.

    Rutgers University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Meghan A Deshais, Ph.D.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: Single case experimental designs will be used.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

April 5, 2023

First Posted

May 8, 2023

Study Start

March 27, 2022

Primary Completion (Estimated)

August 31, 2027

Study Completion (Estimated)

August 31, 2027

Last Updated

May 19, 2026

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will not share

Locations