NCT05844332

Brief Summary

This study was a multicenter observational study with a central registration system and all-case surveillance system without a control group.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
347

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2021

Typical duration for all trials

Geographic Reach
1 country

46 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 17, 2021

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

April 25, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

May 6, 2023

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 27, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 27, 2024

Completed
Last Updated

December 22, 2025

Status Verified

December 1, 2025

Enrollment Period

2.5 years

First QC Date

April 25, 2023

Last Update Submit

December 15, 2025

Conditions

Keywords

LUTATHERA

Outcome Measures

Primary Outcomes (1)

  • Proportion of patients with Renal dysfunction, Myelosuppression, Myelodysplastic syndrome/acute myeloid leukaemia and Hormone release induced crises

    To evaluate the safety about Renal dysfunction, Myelosuppression, Myelodysplastic syndrome/acute myeloid leukaemia and Hormone release induced crises after administration of this drug in a real world setting

    Until 40 weeks after the date of the last dose (64 weeks if 4 doses are administered 8 weeks apart).

Study Arms (1)

LUTATHERA

patients treated with LUTATHERA Injection

Other: LUTATHERA

Interventions

There was no treatment allocation. Patients administered LUTATHERA by prescription could be enrolled.

Also known as: Lutetium oxodotreotide (177Lu)
LUTATHERA

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients treated with this drug for the following indications during a certain post-marketing period • Indication: Somatostatin receptor-positive neuroendocrine tumor

You may qualify if:

  • All patients treated with this drug for the following indications during a certain post-marketing period
  • Indication: Somatostatin receptor-positive neuroendocrine tumor Patients who started to receive this drug before the contract for this study will also be included in the study population and it will be allowed to register them after the contract so that all patients who receive this drug will be included in this study. Patients treated with this drug for off-label indication will also be included in this study to register all patients received this drug.

You may not qualify if:

  • Not applicable

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (46)

Novartis Investigative Site

Nagoya, Aichi-ken, 464 8681, Japan

Location

Novartis Investigative Site

Hirosaki, Aomori, 036 8563, Japan

Location

Novartis Investigative Site

Kamogawa, Chiba, 296-8602, Japan

Location

Novartis Investigative Site

Kashiwa, Chiba, 277 8577, Japan

Location

Novartis Investigative Site

Tōon, Ehime, 7910295, Japan

Location

Novartis Investigative Site

Fukui-shi, Fukui, 910-8526, Japan

Location

Novartis Investigative Site

Gifu, Gifu, 501-1194, Japan

Location

Novartis Investigative Site

Maebashi, Gunma, 371 8511, Japan

Location

Novartis Investigative Site

Sapporo, Hokkaido, 060 8648, Japan

Location

Novartis Investigative Site

Sapporo, Hokkaido, 608543, Japan

Location

Novartis Investigative Site

Akashi, Hyōgo, 673-8558, Japan

Location

Novartis Investigative Site

Kobe, Hyōgo, 6500047, Japan

Location

Novartis Investigative Site

Kanazawa, Ishikawa-ken, 920 8641, Japan

Location

Novartis Investigative Site

Kita-gun, Kagawa-ken, 7610793, Japan

Location

Novartis Investigative Site

Kagoshima, Kagoshima-ken, 890 8520, Japan

Location

Novartis Investigative Site

Kamakura, Kanagawa, 247-8533, Japan

Location

Novartis Investigative Site

Yokohama, Kanagawa-ku, 236-0004, Japan

Location

Novartis Investigative Site

Sendai, Miyagi, 980 8574, Japan

Location

Novartis Investigative Site

Suwa, Nagano, 392-8510, Japan

Location

Novartis Investigative Site

Niigata, Niigata, 951-8566, Japan

Location

Novartis Investigative Site

Kurashiki, Okayama-ken, 7108602, Japan

Location

Novartis Investigative Site

Osaka, Osaka, 5418567, Japan

Location

Novartis Investigative Site

Osaka, Osaka, 553-0003, Japan

Location

Novartis Investigative Site

Sakai, Osaka, 590-0197, Japan

Location

Novartis Investigative Site

Suita, Osaka, 565 0871, Japan

Location

Novartis Investigative Site

Hamamatsu, Shizuoka, 4313192, Japan

Location

Novartis Investigative Site

Iwata, Shizuoka, 438-8550, Japan

Location

Novartis Investigative Site

Shizuoka, Shizuoka, 420-8527, Japan

Location

Novartis Investigative Site

Sunto Gun, Shizuoka, 411 8777, Japan

Location

Novartis Investigative Site

Tokushima, Tokushima, 7708503, Japan

Location

Novartis Investigative Site

Bunkyo-ku, Tokyo, 1138519, Japan

Location

Novartis Investigative Site

Chuo Ku, Tokyo, 104 0045, Japan

Location

Novartis Investigative Site

Koto Ku, Tokyo, 135 8550, Japan

Location

Novartis Investigative Site

Toyama, Toyama, 9300194, Japan

Location

Novartis Investigative Site

Yamagata, Yamagata, 990 9585, Japan

Location

Novartis Investigative Site

Chūō, Yamanashi, 409-3898, Japan

Location

Novartis Investigative Site

Chiba, 260-8717, Japan

Location

Novartis Investigative Site

Fukuoka, 8128582, Japan

Location

Novartis Investigative Site

Fukuoka, 814-0001, Japan

Location

Novartis Investigative Site

Fukushima, 960 1295, Japan

Location

Novartis Investigative Site

Hiroshima, 7348551, Japan

Location

Novartis Investigative Site

Kobe, 650-0017, Japan

Location

Novartis Investigative Site

Kumamoto, 860-8556, Japan

Location

Novartis Investigative Site

Kyoto, 606 8507, Japan

Location

Novartis Investigative Site

Okayama, 7008558, Japan

Location

Novartis Investigative Site

Osaka, 5458586, Japan

Location

Related Links

MeSH Terms

Interventions

lutetium Lu 177 dotatate

Study Officials

  • Novartis Pharmaceuticals

    Novartis Pharmaceuticals

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 25, 2023

First Posted

May 6, 2023

Study Start

December 17, 2021

Primary Completion

June 27, 2024

Study Completion

June 27, 2024

Last Updated

December 22, 2025

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations