Development and Testing of Nutritional Algorithms (NACHO)
Development and Usability Testing of Nutrition Algorithms for Cancer Health Outcomes (NACHO) and Quality of Life During Cancer Treatment
1 other identifier
interventional
130
1 country
1
Brief Summary
The goal of this research study is to develop a nutrition algorithm to optimize nutritional status and improve quality of life during for participants who are completing or have completed cancer treatment. The name of the intervention used in this research study is: Nutrition Algorithm for Cancer Health Outcomes (NACHO) (a technology-based platform that houses the algorithms for the person-centered nutrition program)
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Sep 2026
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 27, 2023
CompletedFirst Posted
Study publicly available on registry
April 24, 2023
CompletedStudy Start
First participant enrolled
September 1, 2026
ExpectedPrimary Completion
Last participant's last visit for primary outcome
January 31, 2027
Study Completion
Last participant's last visit for all outcomes
March 31, 2027
February 6, 2026
February 1, 2026
5 months
February 27, 2023
February 3, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Nutrition Algorithm
Primary study endpoint is development of a nutrition algorithm using the Cancer Nutrition Consortium (CNC) study findings and iteratively refine through an expert Dana-Farber Cancer Institute dietary panel along with consultations from oncology clinicians as needed and feedback from a panel of 4-6 Patient and Family Advisory Council (PFAC) members. Specific to data analyses, chi square, fisher's exact tests, and linear regression will be used to evaluate characteristics associated with changes in taste and different food preferences over time. Findings will inform the development of the algorithms.
12 months
Secondary Outcomes (15)
Acceptability of Nutrition Algorithm for Cancer Health Outcomes (NACHO) Program
Up to 8 months
Participant Satisfaction
Up to 8 months
Panel member characteristics (Aims 1a, 1b, 2a, 2b) - Age
Up to 12 months
Panel member characteristics (Aims 1a, 1b, 2a, 2b) - Gender identity
Up to 12 months
Panel member characteristics (Aims 1a, 1b, 2a, 2b) - Ethnicity
Up to 12 months
- +10 more secondary outcomes
Study Arms (1)
Nutrition Algorithm (NACHO)
EXPERIMENTALStudy procedures will be conducted as follows: * Development of nutrition algorithm by dietitian panel participants with oncology clinician consultation via convened group meetings. * Refinement of draft algorithms through feedback from participants and Family Advisory Council (PFAC) members. * Baseline questionnaires for participants. * Semi-structured interviews and/or focus groups with participants to evaluate algorithm usability and acceptability. * Participant questionnaires.
Interventions
A technology-based platform for a person-centered nutrition program, providing suggested foods and recipes from dietitians.
Eligibility Criteria
You may qualify if:
- Current member of adult PFAC
- \> 18 years old
- \> 18 years old
- Able to speak and read English
- Completed primary treatment (aim 2b) or actively undergoing treatment (aim 2b and aim 3, exploratory)
- Access to a device (e.g., computer, tablet, smartphone) through which they can receive and engage with a REDCap link
You may not qualify if:
- Provider does not recommend
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Dana-Farber Cancer Institutelead
- Cancer Nutrition Consortium Inc.collaborator
Study Sites (1)
Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Marilyn Hammer, MD
Dana-Farber Cancer Institute
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
February 27, 2023
First Posted
April 24, 2023
Study Start (Estimated)
September 1, 2026
Primary Completion (Estimated)
January 31, 2027
Study Completion (Estimated)
March 31, 2027
Last Updated
February 6, 2026
Record last verified: 2026-02
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP
- Time Frame
- Data can be shared no earlier than 1 year following the date of publication
- Access Criteria
- Contact the Belfer Office for Dana-Farber Innovations (BODFI) at innovation@dfci.harvard.edu
The Dana-Farber / Harvard Cancer Center encourages and supports the responsible and ethical sharing of data from clinical trials. De-identified participant data from the final research dataset used in the published manuscript may only be shared under the terms of a Data Use Agreement. Requests may be directed to: \[contact information for Sponsor Investigator or designee\]. The protocol and statistical analysis plan will be made available on Clinicaltrials.gov only as required by federal regulation or as a condition of awards and agreements supporting the research.