Oral Fluid Intake After Extubation
Early Versus Delayed Oral Fluid Intake Initiation (Sipping) After Extubation, Influence on the Feeling of Thirst, Patient Comfort and the Occurrence of Complications.
1 other identifier
interventional
160
1 country
1
Brief Summary
According to the current guidelines the patient is not allowed to drink any fluid at least 2 hours after extubation to prevent complications. However there is no evidence in the literature to support this approach. Because anaesthetic drugs and their side effects changed significantly from their first usage, the investigators can assume that existing approach is obsolete and has no place anymore in the modern medicine. Keeping patient n.p.o (nothing per os) for 2 hours after extubation may lead to patient´s thirst or other discomfort. The aim of the study is to detect whether early oral fluid intake after extubation could lead to safe relief of thirst and to better patient´s comfort overall.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Feb 2023
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 6, 2023
CompletedStudy Start
First participant enrolled
February 1, 2023
CompletedFirst Posted
Study publicly available on registry
April 19, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 16, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
October 16, 2024
CompletedOctober 21, 2024
October 1, 2024
1.7 years
January 6, 2023
October 17, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Assessment of presence or absence of thirst 120 minutes after extubation
Between both groups the presence of anpleasent feeling of thirst will be assessed and compared
During procedure (120 minutes after extubation)
Study Arms (2)
Early fluid intake
EXPERIMENTALStandard Delayed oral fluid
OTHERInterventions
The participant will be randomized into two arms. After the randomization one arm will get the per os fluid intake before the standard time frame.
Eligibility Criteria
You may qualify if:
- patients with planned extubation assigned to the study
- able to swallow the fluid
- willing to participate the study
You may not qualify if:
- patients after upper digestive tract surgery
- patients after trachea surgery
- patients with possible neurological deficiency
- patients after VIII. cranial nerve surgery
- patients not able to swallow
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University Hospital Motol, Charles University in Prague
Prague, Czech Republic, 15006, Czechia
Related Publications (1)
Sedlackova S, Nigrovicova V, Peckova M, Durila M. Immediate "sipping" vs. delayed oral fluid intake after extubation: A randomized controlled trial. J Crit Care. 2026 Feb;91:155212. doi: 10.1016/j.jcrc.2025.155212. Epub 2025 Aug 7.
PMID: 40780083DERIVED
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- prf.
Study Record Dates
First Submitted
January 6, 2023
First Posted
April 19, 2023
Study Start
February 1, 2023
Primary Completion
October 16, 2024
Study Completion
October 16, 2024
Last Updated
October 21, 2024
Record last verified: 2024-10