Oral Lesions in Patients With Eating Disorders

NCT05809778 | Recruiting

• 1 other identifier: RC 18/21
• Study Type: observational
• Target: 81
• Locations: 1 country
• Sites: 1

Brief Summary

Eating disorders (ED) are common among young. Anorexia (AN) and bulimia (BN) are the most prevalent ED. The American Psychiatric Association's guidelines state a 0.3% AN prevalence among young girls and a 0.1 to 4.2% BN prevalence. Men are not excluded: even if ED are more frequent in females (14-18 years), 1 man off to 10 can be diagnosed with ED. Unfortunately, the onset age is decreasing. In the last few years, always more preteens patients are diagnosed with ED: they generally refer a garbled self perception of body image. ED can have oral manifestations, such as: mucosal lesions, dental erosion, glandular hypertrophy, xerostomia and salivary disorders, dental caries These are the most common manifestations observed in patients with eating disorders, after a routine dental visit. There is not strong evidence that dental caries may be directly related to disordered eating habits; as a matter of fact results are controversial. Despite that, all the studies examined agree on the association between signs listed above and food disorders. Univocal percentages have not been reported in the scientific literature. For instance, a systematic review, dated 2016, showed that dental erosion is diagnosed in 45% of ED people, while other studies documented 70% patients affected by erosion. Another example reported is teeth hypersensitivity. According to some studies, 56% of ED patients reported such complaints, instead of other researches documenting 22% hypersensitivity impairment. As for dental caries, results are dissimilar. Authors showed 78% ED subjects diagnosed with dental caries. Other studies reported almost 50% patients with tooth decay, without statistically significant difference in the values between ED people and controls. All these differences are probably due to the different stages of eating disorders and diagnosis, and oral signs found. Different ages are also considered. The primary aim of the study is to evaluate the prevalence of oral cavity lesions among people affected by eating disorders.

Conditions

Eating Disorders

Keywords

Eating disorders; Pral lesions; Prevention; Prevalence

Outcome Measures

Primary Outcomes (1)

• Prevalence of oral lesions in ED affected patients

  Mucosal lesions, dental erosion, glandular hypertrophy, xerostomia or other salivary disorders, and dental caries will be examined.

  At baseline (day 1)

Secondary Outcomes (3)

• To evaluate the association between presence of oral lesions and type of ED

  At baseline (day 1)

• To evaluate the association between presence of oral lesions and patients' global functioning index

  At baseline (day 1)

• To evaluate the association between presence of oral lesions and patients' self-perception about oral health

  At baseline (day 1)

Eligibility Criteria

• Age: 10 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients affected by eating disorders

You may qualify if:

• Diagnosis of ED
• Age between 10 and 18 years

You may not qualify if:

• Parents or caregivers not understanding the Italian language
• Patients affected by other systemic diseases

Sponsors & Collaborators

• IRCCS Burlo Garofolo: lead

Study Sites (1)

Institute for Maternal and Child Health - IRCCS "Burlo Garofolo"

Trieste, Trieste, 34137, Italy

RECRUITING

MeSH Terms

Conditions

Feeding and Eating Disorders

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders

Study Officials

• Milena Cadenaro, MD

  Institute for Maternal and Child Health IRCCS Burlo Garofolo

  STUDY DIRECTOR

Central Study Contacts

Milena Cadenaro, MD

CONTACT

+390403785393; milena.cadenaro@burlo.trieste.it

Valentina Luppieri, MD

CONTACT

00390403785393; valentina.luppieri@burlo.trieste.it

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 29, 2023
• First Posted: April 12, 2023
• Study Start: July 21, 2021
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: May 16, 2025

Record last verified: 2025-05

Locations

IT (1)