Testing the Persuasiveness of Pro-inoculation Arguments

NCT05804825 | Completed

• 1 other identifier: dfjgehea
• Study Type: interventional
• Target: 523
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators will recruit a national sample of parents of 7-10-year-olds to complete an argument strength ranking for either a simple forwarding message or between 3 and 6 randomly selected arguments from an overall set of 50 to 100 messages identified from various online sources. Parents will rate each message they see on measures of perceived argument strength/PME. Parents will also answer sociodemographic questions and then rank the believability of a set of anti-vaccine messages identified in a different study. Study findings will contribute valuable information to understanding the effectiveness of different inoculation messages.

Conditions

Vaccination Hesitancy; Human Papillomavirus Vaccination; Vaccine Refusal

Keywords

misinformation; HPV vaccine; vaccine hesitancy

Outcome Measures

Primary Outcomes (2)

• Argument strength/PME

  Arguments will be rated for their argument strength/message effectiveness

  The outcome measure will be assessed immediately after the participant has viewed each pro-HPV vaccine message if they are in the multiple message condition, or the simple message if they are in the simple message condition stimuli during the survey.

• Misinformation believability

  A rating of the believability/ credibility of vaccine misinformation

  The outcome measure will be assessed immediately after the participant has viewed each misinformation message during the survey.

Study Arms (2)

Simple forewarning message

ACTIVE COMPARATOR

Participants will receive a simple short forewarning message to read and rate.

Behavioral: Simple forewarning message

Argument inoculation messages

EXPERIMENTAL

Participants will view a random sample of 3 text-only short messages (from a corpus of 100 arguments) to read and rate.

Behavioral: Argument inoculation messages

Interventions

Argument inoculation messages BEHAVIORAL

Participants will then be presented with arguments randomly selected by the Qualtrics software algorithm from the full set of messages.

Argument inoculation messages

Simple forewarning message BEHAVIORAL

Participants will be presented with a simple forewarning message.

Simple forewarning message

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male or female parent or legal guardian of an adolescent ages 7-10
• Age eligible child has not yet received any doses of the HPV vaccine
• Resides in the United States
• English speaking
• Completed informed consent

You may not qualify if:

• Unable to read English at a 6th grade literacy level
• Age \< 18
• Does not have a child within the age range of 7-10
• Age-eligible child has received 1 or more doses of the HPV vaccine
• Unwilling or unable to provide informed consent to study participation

Sponsors & Collaborators

• University of Pennsylvania: lead

Study Sites (1)

UPenn

Philadelphia, Pennsylvania, 19104, United States

Location

MeSH Terms

Conditions

Vaccination Hesitancy; Vaccination Refusal; Communication

Condition Hierarchy (Ancestors)

Treatment Refusal; Treatment Adherence and Compliance; Health Behavior; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: randomized discrete choice modeling experiment design

Study Record Dates

• First Submitted: October 20, 2022
• First Posted: April 7, 2023
• Study Start: May 4, 2023
• Primary Completion: May 24, 2023
• Study Completion: May 24, 2023
• Last Updated: July 11, 2023

Record last verified: 2023-07

Locations

US (1)