Feasibility Trial of a Multi-level Media Production and Social Marketing Campaign to Reduce HPV Vaccine Hesitancy

NCT05860725 | Recruiting

• 1 other identifier: SBS-5519
• Study Type: interventional
• Target: 220
• Locations: 1 country
• Sites: 1

Brief Summary

Since 2019, the HPV working group of the University of Virginia Cancer Center's Southwest Virginia Community Advisory Board has developed and executed strategies to increase regional HPV vaccination rates. Members collaboratively developed Appalachian Voices for Health, a multi-level media production and social marketing intervention. This novel intervention builds on the past efforts of the working group and the engaged organizations; takes into account the impact of vaccine hesitancy on HPV vaccination uptake; and incorporates best practices. Through the intervention, Nursing and Dental Assistant students from Mountain Empire Community College will develop PSAs after receiving training about HPV vaccination and health communication. These PSAs will be used in a social marketing campaign executed through a regional transportation system managed by Mountain Empire Older Citizens. Specifically, the trial's aims are three-fold: assess the intervention's impact on community members' and students' HPV vaccine hesitancy (Aim 1) and perceptions and actions related to HPV vaccination (Aim 2) and evaluate other feasibility indicators at the community-, student-, organizational-, and process levels (Aim 3). The research team will use a concurrent mix-methods approach to assess feasibility indicators. Aims will be assessed using surveys, focus groups, meeting minutes, and implementation records. Data will be analyzed using descriptive and inferential statistics and content coding. Determination of the intervention's feasibility will consider the achievement benchmarks for feasibility indicators individually and collectively. Data will be used to inform refinement and future testing of Appalachian Voices for Health.

Conditions

Human Papillomavirus Infection; Vaccination Hesitancy

Outcome Measures

Primary Outcomes (2)

• Vaccination hesitancy scale modified for the HPV vaccine (VHS-HPV)

  validated instrument; 9 items on a response scale of 1-5 (strongly disagree to strongly agree) with higher scores indicating greater hesitancy

  Change in community members' self-reported VHS-HPV score pre-post intervention (14 week period / Phase 2)

• Vaccination hesitancy scale modified for the HPV vaccine (VHS-HPV)

  validated instrument; 9 items on a response scale of 1-5 (strongly disagree to strongly agree) with higher scores indicating greater hesitancy

  Change in Health Sciences students' self-reported VHS-HPV score pre-post intervention (6 week period / Phase 1)

Secondary Outcomes (2)

• Vaccination hesitancy scale (VHS)

  Change in community members' self-reported VHS score pre-post intervention (14 week period / Phase 2)

• Vaccination hesitancy scale (VHS)

  Change in Health Science students' self-reported VHS score pre-post intervention (6 week period / Phase 1)

Study Arms (3)

PSA Development (Phase 1)

EXPERIMENTAL

Behavioral: PSA Development

Social Marketing Campaign (Phase 2)

EXPERIMENTAL

Behavioral: HPV vaccination focused social marketing campaign

Organizational Stakeholders

NO INTERVENTION

Organizational stakeholders from organizations involved in Phase 1 and 2 will take part in a focus group after their respective phases have been completed to learn more about their experience.

Interventions

PSA Development BEHAVIORAL

Health sciences students from a regional community college in Appalachian Virginia will be asked to to develop and submit a public service announcement (PSA) and to watch virtual training webinars that support the development of the PSAs. They will also be asked to complete surveys at three time points: before the PSA contest starts, after the PSA contest ends, and upon submitting a PSA.

PSA Development (Phase 1)

HPV vaccination focused social marketing campaign BEHAVIORAL

Community members who use a regional health services focused non-profits rideshare buses and/or view their social media pages will be exposed to a 12-week social marketing campaign that uses PSAs developed in Phase 1. Community members will also complete surveys at three time points: before the start of the social marketing campaign, during the social marketing campaign, and after the social marketing campaign.

Social Marketing Campaign (Phase 2)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18 or older
• enrolled as a student in one of the regional community college's health sciences programs (Phase 1 only)
• ride the regional health services focused non-profit's rideshare buses or view their social media during one or more of the three survey periods (Phase 2 only)
• work for either the regional community college or non-profit AND were involved in supporting the execution of the study components within their organization.

You may not qualify if:

• Under 18

Sponsors & Collaborators

• University of Virginia: lead

Study Sites (1)

University of Virginia

Charlottesville, Virginia, 22903, United States

RECRUITING

MeSH Terms

Conditions

Papillomavirus Infections; Vaccination Hesitancy

Condition Hierarchy (Ancestors)

Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Communicable Diseases; Infections; DNA Virus Infections; Virus Diseases; Tumor Virus Infections; Genital Diseases; Urogenital Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Vaccination Refusal; Treatment Refusal; Treatment Adherence and Compliance; Health Behavior; Behavior

Central Study Contacts

Kathleen J Porter, PhD RD

CONTACT

434-270-6599; kjp9c@virginia.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: February 28, 2023
• First Posted: May 16, 2023
• Study Start: March 13, 2023
• Primary Completion: May 30, 2024
• Study Completion: May 30, 2024
• Last Updated: May 9, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)