NCT05797402

Brief Summary

The investigators aim to establish a clinical database and biobank for elderly patients with multiple diseases. The collected data will include demographic information, comorbidity characteristic, FRAIL scale, age-adjusted Charlson comorbidity index, relevant blood tests, the results of imaging examination, prescription of drugs, length of hospital stay, number of overall rehospitalizations and death. With this database, the investigators intend to formulate an individualized treatment strategy for these patients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10,000,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2013

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2013

Completed
10.1 years until next milestone

First Submitted

Initial submission to the registry

February 22, 2023

Completed
1 month until next milestone

First Posted

Study publicly available on registry

April 4, 2023

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 15, 2023

Completed
17 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2023

Completed
Last Updated

April 4, 2023

Status Verified

April 1, 2023

Enrollment Period

10.4 years

First QC Date

February 22, 2023

Last Update Submit

April 2, 2023

Conditions

Comorbidities and Coexisting ConditionsOld Age; Debility

Keywords

Cognition DisordersFrailtyCoronary heart diseaseAtrial fibrillationStrokeHeart failureHypertensionValvular heart disease

Outcome Measures

Primary Outcomes (1)

  • The incidence of geriatric syndromes including falls, cognitive impairment, dizziness and frailty

    collection of clinical data in the medical record and follow-up update

    1 year

Secondary Outcomes (1)

  • The incidence of survival rate

    1 year

Study Arms (3)

young-aged patients

Patients aged 18 to 45 years old.

middle-aged patients

Patients aged 46 to 64 years old.

elderly patients

Patients aged 65 and older.

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

hospital based group

You may qualify if:

  • (1) written and informed consent, (2) participants aged 18 years or older.

You may not qualify if:

  • (1) Unwilling to participate in the study, (2) Unable or unwilling to cooperate with the baseline or follow-up data collection.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Beijing Anzhen Hospital, Capital Medical University

Beijing, 100029, China

RECRUITING

Related Publications (2)

  • Huang X, Zheng W, Wang X, Suo M, Zhao X, Nie S. Association between Charlson Comorbidity Index and in-hospital outcomes among aortic stenosis patients undergoing aortic valve replacement: an observational study at the National Clinical Research Center for Cardiovascular Diseases. BMJ Open. 2025 Jun 17;15(6):e083677. doi: 10.1136/bmjopen-2023-083677.

    PMID: 40527568DERIVED

  • Zheng W, Huang X, Wang X, Suo M, Yan Y, Gong W, Ai H, Que B, Nie S. Impact of multimorbidity patterns on outcomes and treatment in patients with coronary artery disease. Eur Heart J Open. 2024 Mar 27;4(2):oeae009. doi: 10.1093/ehjopen/oeae009. eCollection 2024 Mar.

    PMID: 38544919DERIVED

MeSH Terms

Conditions

FrailtyCognition DisordersCoronary DiseaseAtrial FibrillationStrokeHeart FailureHypertensionHeart Valve Diseases

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and SymptomsNeurocognitive DisordersMental DisordersMyocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesArrhythmias, CardiacCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Central Study Contacts

Shao-ping Nie, MD,PhD

CONTACT

8613701186772spnie@ccmu.edu.cn

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Medicine,Director,Department of Cardiology

Study Record Dates

First Submitted

February 22, 2023

First Posted

April 4, 2023

Study Start

January 1, 2013

Primary Completion

May 15, 2023

Study Completion

June 1, 2023

Last Updated

April 4, 2023

Record last verified: 2023-04

Locations

CN(1)