NCT04919044

Brief Summary

An aging society is known as having at least 7% of its population aged 65 and older, whereas 14% or more known to be an aged nation. Age has a detrimental effect on the physical performance and the muscle strength, the reduced muscle strength, mass and structure in the elderly are due to aging, disuse and inactivity. In the elderly, the reduction of muscle strength is faster than the associated loss of muscle mass. The maximum isometric strength of knee extensors and muscle mass decrease due to aging. The combination of quadriceps and handgrip strength weakness in the elderly is associated with the poorest scores on quality of life, GP contact-time, gait speed, hospitalization and disability in daily living. Quadriceps weakness among elderly is also proved to be a contributing factor to fall among frail nursing home residents. A systematic review and meta-analysis revealed that quadriceps muscle weakness was associated with greater risk of developing knee osteoarthritis during 2.5 to 14 year follow-up in either gender. In overall, aging cause reduce muscle strength, especially quadriceps muscle, can cause many others negative consequences, thus a study of effect motor imagery on quadriceps muscle strength in community-dwelling elderly should be carried out, if this study is proven to effectively, motor imagery technique can be widely utilized on bedridden elderly or elderly who have severe cardiovascular disease who unable to perform physical activity to maintain or improve their muscle strength.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 2, 2021

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 9, 2021

Completed
2 months until next milestone

Study Start

First participant enrolled

August 8, 2021

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 10, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 10, 2022

Completed
Last Updated

September 2, 2021

Status Verified

September 1, 2021

Enrollment Period

6 months

First QC Date

June 2, 2021

Last Update Submit

September 1, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Quadriceps Strength

    The participants were in sitting position, hand-held dynamometer was place on the shin of the tibia just above medial and lateral malleolus. Before measuring the quadriceps strength, participant's knees were held in 90-degree flexion and feet not in contact with the floor. The participants were instructed to straighten leg by pushing against hand-held dynamometer. Peak force generated by dynamometer was recorded. The measurement was repeated three times to take an average of 3.

    Change from baseline Quadriceps strength at 4 weeks

Study Arms (2)

Motor Imagery

EXPERIMENTAL

The participants were instructed to imagine and visualize to straighten both knees with eyes closed. You have to see and feel only what you would see and feel if you had to perform the action to straighten both of your knees in sitting position. Imagine the movement using the most comfortable way for you, and make sure not to contract your muscles.

Other: Motor Imagery Training

Control

NO INTERVENTION

No intervention provided.

Interventions

The number of imagined contractions were 34 trials, each trial was 10 seconds with 5seconds rest between each trial and 2 minutes' rest was given after first 17 trials.

Motor Imagery

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Both gender
  • Aged 60 and above
  • Participant who has a mean score of more than 3 in Movement Imagery Questionnaire-3
  • Participant who scored 22 and above in MONTREAL COGNITIVE ASSESSMENT (MOCA) VERSION 7.1

You may not qualify if:

  • Individual with neurological impairment or musculoskeletal injury.
  • Participants unable to follow the instructions.
  • Individuals using any anti-epileptic drugs and/or psychiatric drugs.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universiti Tunku Abdul Rahman

Kajang, Selangor, 43000, Malaysia

RECRUITING

MeSH Terms

Conditions

Frailty

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Outcome assessor did not know participants belonged to which group.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

June 2, 2021

First Posted

June 9, 2021

Study Start

August 8, 2021

Primary Completion

February 10, 2022

Study Completion

February 10, 2022

Last Updated

September 2, 2021

Record last verified: 2021-09

Locations