The Research of Novel Electrolyzed Water Spray to Eradicate Bacteria E-coli and an Attenuated Human Flu Virus

NCT05797103 | Completed DMC

• 1 other identifier: jia19961018
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to test whether spraying the hand of patients by use of the novel electrolyzed water spray will decrease the number of bacteria E-coli and the virus titer of an attenuated human flu virus.

Conditions

Bacterial Growth; Novel Influenza A (H1N1)

Keywords

Electrolyzed water device; Hydroxyl radical; Tap water; Spray; E-coli; Human flu virus

Outcome Measures

Primary Outcomes (1)

• Flush and eradicate the number of bacteria E-coli on human hands.

  Calculate the total number of bacterial colonies formed, expressed as CFU, and the total number of bacterial colonies (CFU) is the total number of colonies formed on the surface of a solid medium in 1 ml of a water sample. Viral titer (TCID50) indicates the minimum number of bacteria or amount of toxin required to infect half of an animal of a certain body weight or age by a specified route of infection within a specified time.

  10 seconds

Study Arms (2)

electrolyzed water spray group

EXPERIMENTAL

Participants with bacteria E-coli and an attenuated human flu virus on their hands will receive one treatment with the novel electrolyzed water and complete the questionnaire.

Device: A novel electrolyzed water spray reduces numbers of bacteria E-coli and an attenuated human flu virus on human hands

untreated tap water group

EXPERIMENTAL

Participants with bacteria E-coli and an attenuated human flu virus on their hands will receive one treatment with the untreated tap water and complete the questionnaire.

Device: A novel electrolyzed water spray reduces numbers of bacteria E-coli and an attenuated human flu virus on human hands

Interventions

A novel electrolyzed water spray reduces numbers of bacteria E-coli and an attenuated human flu virus on human hands DEVICE

Electrolyzed water spray group will use the novel electrolyzed water spray to flush the hands that daub E. coli and attenuated human influenza virus H1N1 for 6 seconds per hand, and then use 4 seconds to collect a sample of the water flowing from the sprayed hand and apply it to the plate. Untreated tap water group will use the untreated tap water spray to flush the hands that daub E. coli and attenuated human influenza virus H1N1 for 6 seconds per hand, and then use 4 seconds to collect a sample of the water flowing from the sprayed hand and apply it to the plate.

electrolyzed water spray group; untreated tap water group

Eligibility Criteria

• Age: 24 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age 18-60 years.
• Male or female of any race and ethnicity.
• Subject agrees to comply with study requirements.

You may not qualify if:

• Severely unhealthy participants.
• years or older.
• Subjects with severe medical condition(s) that in the view of the investigator prohibits participation in the study.
• Dermatologic disease such as psoriasis or atopic dermatitis which may have inherently abnormal antimicrobial peptide levels.
• Subject has Netherton's syndrome or other genodermatoses that result in a defective epidermal barrier.
• Immunocompromised subjects, or with a history of active or malignant disease as determined by the participant's medical history.
• Subjects with a history of psychiatric disease or history of alcohol or drug abuse that would interfere with the ability to comply with the study protocol.
• Subjects with significant concurrent medical condition(s) at screening that in the view of the investigator prohibits participation in the study

Sponsors & Collaborators

• Dove Medical Press Ltd: lead

Study Sites (1)

Huinuode Biotechnology Co., Ltd.

Qingdao, China

Location

MeSH Terms

Conditions

Escherichia coli Infections

Condition Hierarchy (Ancestors)

Enterobacteriaceae Infections; Gram-Negative Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Infections

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Masking Details: This is an open label, two arm clinical study
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: NETWORK
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 27, 2023
• First Posted: April 4, 2023
• Study Start: January 29, 2023
• Primary Completion: July 2, 2023
• Study Completion: July 27, 2023
• Last Updated: August 1, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)