NCT01037855

Brief Summary

This is an observational study of safety and occurrence of influenza-like illness following administration of flu cell culture derived adjuvanted swine origin A (H1N1) pandemic subunit vaccine in subjects 6 months of age and older.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,028

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2009

Geographic Reach
4 countries

10 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2009

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

December 20, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 23, 2009

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2010

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2011

Completed
Last Updated

March 14, 2017

Status Verified

March 1, 2017

Enrollment Period

6 months

First QC Date

December 20, 2009

Last Update Submit

March 13, 2017

Conditions

Keywords

Swine Flu H1N1 vaccineAdjuvanted flu cell culture derived

Outcome Measures

Primary Outcomes (2)

  • To quantify the safety of Flu Cell Culture Derived Adjuvanted Swine Origin A(H1N1) Pandemic Subunit Vaccine in actively monitored subjects

    6 months

  • To characterize the incidence of AEs in specific age groups following an active surveillance of vaccinated subjects

    6 months

Secondary Outcomes (1)

  • To assess the occurrence of laboratory confirmed H1N1sw and influenza-like illness following vaccination

    6 Months

Study Arms (6)

Group 1: 6-23 months

Other: Non-intervention observational study

Group 2: 2-8 years

Other: Non-intervention observational study

Group 3: 9-17 years

Other: Non-intervention observational study

Group 4: 18-44 years

Other: Non-intervention observational study

Group 5: 45-60 years

Other: Non-intervention observational study

Group: >60 years

Other: Non-intervention observational study

Interventions

Non-intervention observational study

Group 1: 6-23 monthsGroup 2: 2-8 yearsGroup 3: 9-17 yearsGroup 4: 18-44 yearsGroup 5: 45-60 yearsGroup: >60 years

Eligibility Criteria

Age6 Months+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

population of children, adolescents, adults and elderly

You may qualify if:

  • Age ≥ 6 months
  • Subjects will be vaccinated with Flu Cell Culture Derived Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Vaccine, independently of this study.
  • Subjects or parent/guardian willing to provide informed consent prior to vaccination administration and complete all of the study, including follow-up contact

You may not qualify if:

  • Received any prior H1N1 vaccination

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (10)

Clinica Indisa

Av. Santa Maria, Santiago Metropolitan, 1810, Chile

Location

Fundación Universitaria de Ciencias de Salud- Hospital San José Calle

Bogotá, Colombia

Location

Nueva EPS: Centro de Especialistas Barrios Unidos - MEDERI

Calle 66 # 40-07 - Bogotá, Colombia

Location

Hospital local de Yopal E.S.E

Calle 9 No. 24-37 - Yopal, Casanare, Colombia

Location

Clinica del Country

Carrera 16 No. 82-57 Bogotá, Colombia

Location

Hospital Universitario Infantil San José

Carrera 52 No. 67a-71 - Barrios Unidos - Bogotá, Colombia

Location

CAIMED - Centro de Atencion e Investigación Medica

Cra. 42 A No. 17-50, Colombia

Location

Unknown Facility

Augustenburger Platz 1, State of Berlin, Germany

Location

Policlinique Médicale Universitaire

Rue Du Bugnon 44, Ch-1011 Lausanne, Switzerland

Location

Institute of Social and Preventive Medicine, Division of Communicable Diseases

Hirschengraben 84, Ch-8001 Zürich, Switzerland

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 20, 2009

First Posted

December 23, 2009

Study Start

December 1, 2009

Primary Completion

June 1, 2010

Study Completion

January 1, 2011

Last Updated

March 14, 2017

Record last verified: 2017-03

Locations