Circadian and Seasonal Variation in Acute Myocardial Infarction
1 other identifier
observational
100
1 country
1
Brief Summary
Circadian and seasonal variation in acute myocardial infarction .
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jun 2023
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 29, 2023
CompletedFirst Posted
Study publicly available on registry
March 29, 2023
CompletedStudy Start
First participant enrolled
June 1, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2026
CompletedMarch 29, 2023
March 1, 2023
8 months
January 29, 2023
March 27, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Circadian and seasonal variation in acute myocardial infarction
Reporting the presence or absence of difference in electrocardiogram ,Echo and d-Dimer between patients presented with acute myocardial infarction in different seasons.
Baseline
Eligibility Criteria
Sample size was calculated using Epi- Info7. Expected frequency of cardiac onset is 15%. Based on this frequency and with a confidence limits of 6% and a confidence level of 90%, the sample needed for the study was estimated to be about from 138 patients and 196 at 95% CI .The sample will be calculated in the seasons of extreme seasonal changes at 2023, 2024
You may qualify if:
- All patients above (16) years old 2.Complaint occur during acute climate changes
You may not qualify if:
- Patients below 16 years old 2.Complaint during normal climate
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assiut University
Asyut, Egypt
Related Publications (2)
Nagarajan V, Fonarow GC, Ju C, Pencina M, Laskey WK, Maddox TM, Hernandez A, Bhatt DL. Seasonal and circadian variations of acute myocardial infarction: Findings from the Get With The Guidelines-Coronary Artery Disease (GWTG-CAD) program. Am Heart J. 2017 Jul;189:85-93. doi: 10.1016/j.ahj.2017.04.002. Epub 2017 Apr 12.
PMID: 28625385BACKGROUNDThosar SS, Butler MP, Shea SA. Role of the circadian system in cardiovascular disease. J Clin Invest. 2018 Jun 1;128(6):2157-2167. doi: 10.1172/JCI80590. Epub 2018 Jun 1.
PMID: 29856365BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident doctor of critical care internal medicine
Study Record Dates
First Submitted
January 29, 2023
First Posted
March 29, 2023
Study Start
June 1, 2023
Primary Completion
February 1, 2024
Study Completion
February 1, 2026
Last Updated
March 29, 2023
Record last verified: 2023-03
Data Sharing
- IPD Sharing
- Will not share