The Relationship Between Myocardial Blush Grade and T-P-e Interval and QRS Width: Impact on In-Hospital Outcome After Successful Primary Percutaneous Coronary Intervention

NCT05593822 | Unknown

• 1 other identifier: Relationship between PPCI &ECG
• Study Type: interventional
• Target: 80
• Locations: 0 countries
• Sites: N/A

Brief Summary

Aim of the work: Primary aim; is to assess relation between non invasive ECG findings, Tpe interval and QRS width and MBG in in patients with successful PCI in patients with STEMI. Secondary aim; is to assess impact of Tpe, QRS width and MBG on in hospital outcome

Conditions

Myocardial Infarction

Outcome Measures

Primary Outcomes (3)

• QRS width changes before and after PCI

  All the patients will be suspected to the following Electrocardiogram At admission and 90 minutes after the PCI, -QRS complex will be measured from the start to the end of the complex,(in milli-seconds)

  6 month

• Tpe interval changes before and after PCI

  All the patients will be suspected to the following Electrocardiogram At admission and 90 minutes after the PCI, -Tpe interval will be measured from the peak of T wave to the end of it (in milli-seconds)

  6 month

• MBG during PCI .

  primary PCI The contrast density in the distal myocardial region of the IRA is graded in comparison with the blush of non-IRA myocardial regions on cine film at 25 frames per second on the best projection along at least 3 cardiac cycles duration to ensure washout. * Patients with no myocardial blush are graded as MBG 0, * those with minimal myocardial blush are graded as MBG 1, * those with moderate myocardial blush are graded as MBG 2 * and patients with normal myocardial blush are graded as MBG 3.

  1 year

Secondary Outcomes (1)

• left ventricular function

  1 year

Study Arms (1)

patient with STEMI

OTHER

Procedure: primary percutaneous intervention

Interventions

primary percutaneous intervention PROCEDURE

percutaneous catheterization through peripheral arteries to coronary arteries

patient with STEMI

Eligibility Criteria

• Age: 25 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Typical ongoing ischemic chest pain for \>30 minutes
• ST elevation ≥1mm in ≥2 contiguous leads (2 mm for pericordial leads)
• Successful primary PCI (patent infarct related artery)

You may not qualify if:

• Patients with known bundle branch block
• Patients with advanced degree of atrioventricular block or electrolyte disturbances.
• Permanent pacemaker
• Cardiomyopathies, chronic kidney disease.
• Previously revascularized patients either by PCI or CABG surgery

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident doctor

Study Record Dates

• First Submitted: October 9, 2022
• First Posted: October 25, 2022
• Study Start: October 1, 2022
• Primary Completion: October 1, 2025
• Study Completion: December 1, 2025
• Last Updated: October 27, 2022

Record last verified: 2022-10