NCT05783583

Brief Summary

A clinical study has been identified as a requirement for the RDSL (Theia). This study involves a clinical comparison of the imaging from the RDSL with that of a predicate device. The clinical evaluation showed that there remains some residual risk in the practitioner's ability to use the imaging from the RDSL to detect pathologies at the same level as when using the imaging function on a predicate device. The aim of this comparative study is to determine the degree, if any, of difference in using images captured from the RDSL for clinical inspection of pathologies, when compared to images captured from a predicate device. Due to the involvement of real patients during the study, ethics approval was sought prior to commencement. This study is limited to the clinical benefits of the device. An additional Human factors study has been conducted to assess the useability of the device Images were taken of healthy eyes and eyes with pathology (with images of several pathologies from each major pathology group to give a full range) on both the predicate device, and the RDSL.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
49

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Oct 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2022

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 5, 2023

Completed
15 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 20, 2023

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

January 30, 2023

Completed
2 months until next milestone

First Posted

Study publicly available on registry

March 24, 2023

Completed
Last Updated

April 7, 2023

Status Verified

April 1, 2023

Enrollment Period

3 months

First QC Date

January 30, 2023

Last Update Submit

April 5, 2023

Conditions

Outcome Measures

Primary Outcomes (3)

  • Diagnostic Confidence

    How confident the practitioner is in respect of their identification of a pathology from image on a scale of 1-5, with 5 being completely confident and 1 being not confident. Images reviewed via online from.

    Within 1 week after data collection

  • Image Clarity

    The rating of clarity of image by the practitioner on a scale of 1-5, with 5 being excellent clarity and 1 being low clarity. Images reviewed via online from.

    Within 1 week after data collection

  • Identification of Pathology

    % accuracy of identification of pathology shown or healthy eye. Images reviewed via online from.

    Within 1 week after data collection

Study Arms (1)

Enrolled participants

Adult human subjects showing either healthy eyes or specific ocular pathologies.

Device: Remote Digital Slit Lamp

Interventions

Slit Lamp Examination

Enrolled participants

Eligibility Criteria

Age21 Years - 99 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

community

You may qualify if:

  • Healthy eye or ocular pathology

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Vision Inc Corporate Office

Atlanta, Georgia, 300096, United States

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Study Officials

  • John Bankowski, DOO

    National Vision Inc

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 30, 2023

First Posted

March 24, 2023

Study Start

October 1, 2022

Primary Completion

January 5, 2023

Study Completion

January 20, 2023

Last Updated

April 7, 2023

Record last verified: 2023-04

Locations