NCT05495555

Brief Summary

The objective is to assess the efficiency (as measured by phaco time, aspiration time, and fluid use) of the hybrid tip in removing cataract grade 3 \& 4 in high and low intraocular pressure (IOP) settings.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
51

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Aug 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 1, 2022

Completed
2 days until next milestone

Study Start

First participant enrolled

August 3, 2022

Completed
7 days until next milestone

First Posted

Study publicly available on registry

August 10, 2022

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 7, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 7, 2024

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

March 11, 2025

Completed
Last Updated

March 11, 2025

Status Verified

February 1, 2025

Enrollment Period

1.5 years

First QC Date

August 1, 2022

Results QC Date

January 15, 2025

Last Update Submit

February 19, 2025

Conditions

Outcome Measures

Primary Outcomes (3)

  • Phaco Time

    Day 0 (surgical visit)

  • Aspiration Time

    Day 0 (surgical visit)

  • Fluid Use

    Day 0 (surgical visit)

Secondary Outcomes (1)

  • Central Corneal Thickness Change From Baseline

    baseline and 1 week postoperative

Other Outcomes (1)

  • Cumulative Dissipated Energy

    Day 0 (surgical visit)

Study Arms (2)

High IOP setting

Cataract removal with high IOP setting

Device: INTREPID® Hybrid tip

Low IOP setting

Cataract removal with low IOP setting

Device: INTREPID® Hybrid tip

Interventions

INTREPID® Hybrid tip for cataract removal

High IOP settingLow IOP setting

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Eligible test subjects will be 50 years of age or older and who are eligible to undergo sequential bilateral uncomplicated cataract surgery.

You may not qualify if:

  • Patient under 50 years of age
  • Unable to complete sequential bilateral cataract surgery in both eyes by the same surgeon (JS)
  • Patient cataract surgery complicated by posterior capsular tear
  • Any disease state deemed by PI that increases risk of complicated cataract surgery (ie Pseudoexfoliation syndrome, zonular dehiscence, history of eye trauma. RA, prior refractive surgery, etc)
  • The principal investigator reserves the right to declare a patient ineligible or non- evaluable based on medical evidence that indicates they are unsuitable for the trial.
  • Pregnancy has a known effect on the stability of refractions and visual acuity. As such, subjects who become pregnant during the study will not be discontinued but their data may be excluded from analyses of effectiveness.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cataract & Laser Institute

Medford, Oregon, 97504, United States

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Results Point of Contact

Title
Dr Justin Spaulding
Organization
Cataract & Laser Institute

Study Officials

  • Justin Spaulding, DO

    Cataract & Laser Institute

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 1, 2022

First Posted

August 10, 2022

Study Start

August 3, 2022

Primary Completion

February 7, 2024

Study Completion

February 7, 2024

Last Updated

March 11, 2025

Results First Posted

March 11, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will not share

Locations