NCT07028359

Brief Summary

This randomized controlled trial evaluated the effectiveness of the Sharp Health Companion App, a smartphone-based digital health tool, compared to standard printed instructions for supporting older adults undergoing cataract surgery. The study enrolled 200 patients aged 39-86 from a high-volume ophthalmology practice. Participants were randomly assigned to either a printed instructions group or a group using the mobile app built on Apple's CareKit platform. Outcomes included surgery cancellation rates, day-of-surgery delays, medication adherence (both subjective and objective), visual acuity, and patient satisfaction. The app significantly reduced same-day surgery delays and improved objective medication adherence. The study was completed between December 2022 and January 2024 and was approved by the Sharp HealthCare Institutional Review Board (IRB #2209803).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2022

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2022

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2024

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2024

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

June 11, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

June 19, 2025

Completed
Last Updated

June 19, 2025

Status Verified

June 1, 2025

Enrollment Period

1.2 years

First QC Date

June 11, 2025

Last Update Submit

June 11, 2025

Conditions

Keywords

Cataract surgeryMobile HealthMhealthDigital healthMedication adherencePerioperative careOlder adultsSharp health companion appCareKitiPhone

Outcome Measures

Primary Outcomes (3)

  • Objective Medication Adherence Rate

    Percentage of patients whose surgery was delayed by two or more hours on the day of surgery due to noncompliance with preparation protocols (e.g., dietary, arrival time, or documentation errors).

    30 days post-surgery

  • Same-Day Cataract Surgery Delay Rate

    Percentage of patients whose surgery was delayed by two or more hours on the day of surgery due to noncompliance with preparation protocols (e.g., dietary, arrival time, or documentation errors).

    Day of Surgery

  • Cataract Surgery Cancellation Rate

    Percentage of patients whose surgery was delayed by two or more hours on the day of surgery due to noncompliance with preparation protocols (e.g., dietary, arrival time, or documentation errors).

    Day of schedule surgery

Secondary Outcomes (5)

  • Self-Reported Medication Adherence

    30 days post-surgery

  • Visual Acuity Outcome

    Baseline to 30 days post-surgery

  • Patient Reported Surgical Experience Score

    30 days post-surgery

  • Postoperative custodial macular edema (CME) incidence

    30 days post-surgery

  • Postoperative Iritis Incidence

    30 days post-surgery

Study Arms (2)

Group 1: Printed Instructions + Phone Reminders

ACTIVE COMPARATOR

Participants in this arm received printed instructions for cataract surgery preparation and recovery, along with automated phone reminders. They used a printed checklist to track medication adherence. This group did not receive the Sharp Health Companion App.

Behavioral: Printed Instructions with Phone Reminders

Group 2: Sharp Health Companion Mobile App Group

EXPERIMENTAL

Participants in this arm used the Sharp Health Companion App, a CareKit-based iPhone application, to receive digital pre- and postoperative instructions, medication reminders, and educational content. The app tracked medication adherence and surgical prep. Printed instructions were provided as backup.

Behavioral: Sharp Health Companion App (CareKit)

Interventions

Participants received paper-based instructions for perioperative care, including medication, fasting, and follow-up logistics. Automated phone calls were sent before surgery to reinforce preparation. Participants used a printed checklist to self-report eye drop adherence.

Group 1: Printed Instructions + Phone Reminders

The Sharp Health Companion App delivered interactive digital perioperative checklists, medication adherence prompts, COVID-19 protocol reminders, symptom tracking, and educational videos via iPhone. Participants logged their medication use in real time on the Sharp Health Companion App. Printed instructions were provided as a backup.

Group 2: Sharp Health Companion Mobile App Group

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Scheduled for first-time cataract surgery at Sharp HealthCare Best-corrected visual acuity of 20/40 or worse Able to provide informed consent English-speaking For Group 2: possession of an iPhone and ability to use smartphone functions (e.g., Face ID or passcode)

You may not qualify if:

  • History of prior cataract surgery Significant cognitive, visual, or physical impairment preventing use of the app Inability to follow study procedures or complete follow-up Lack of access to compatible technology (Group 2 only)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sharp Rees-Stealy Medical Group

San Diego, California, 92123, United States

Location

MeSH Terms

Conditions

CataractMedication Adherence

Condition Hierarchy (Ancestors)

Lens DiseasesEye DiseasesPatient CompliancePatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Study Officials

  • Tommy Korn, MD

    Sharp Rees-Stealy Medical Group and Sharp HealthCare

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Group assignments were concealed from investigators, care teams, and outcomes assessors using a digital randomization app and unique study identifiers.
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: Participants were randomly assigned 1:1 to printed instructions with phone reminders (Group 1) or to the Sharp Health Companion mobile app (Group 2), built using CareKit platform
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 11, 2025

First Posted

June 19, 2025

Study Start

December 1, 2022

Primary Completion

February 28, 2024

Study Completion

September 30, 2024

Last Updated

June 19, 2025

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will not share

Locations