Registry of Acute Ischemic Stroke With Large- or Medium-vessel Occlusion
LOMEVO
The Multicenter, Prospective, Real-world Registry of Acute Ischemic Stroke With Large- or Medium-vessel Occlusion
1 other identifier
observational
50,000
1 country
1
Brief Summary
This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 2023
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 7, 2023
CompletedFirst Posted
Study publicly available on registry
March 22, 2023
CompletedStudy Start
First participant enrolled
April 25, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 30, 2032
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 30, 2032
May 30, 2024
May 1, 2024
9 years
March 7, 2023
May 28, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
modified Rankin Scale (mRS) score
Ordinal distribution of mRS at 90±7 days; modified Rankin scale (range, 0 to 6, with a score of 0 indicating no disability, 1 no clinically significant disability, 2 slight disability, 3 moderate disability but remaining able to walk unassisted, 4 moderately severe disability, 5 severe disability, and 6 death)
90±7 days
Secondary Outcomes (11)
Excellent functional outcome
90±7 days
Good functional outcome
90±7 days
mRS 0-3
90±7 days
Change of National Institutes of Health Stroke Scale (NIHSS)
24 hours
Change of National Institutes of Health Stroke Scale (NIHSS)
7 days
- +6 more secondary outcomes
Other Outcomes (5)
Incidence of clinically significant intracranial hemorrhage
36 hours
Incidence of any intracranial hemorrhage
36 hours
All-cause mortality
90±7 days
- +2 more other outcomes
Study Arms (1)
acute ischemic stroke with large- or medium-vessel occlusion
acute ischemic stroke patients with large- or medium-vessel occlusion including all treatments.
Interventions
Visits at 90±7 days after stroke onset were conducted by trained and blinded investigators, with face-to-face, telephone call or Internet access.
Eligibility Criteria
Patients with acute ischemic stroke due to large- or medium-vessel occlusion will be enrolled and no additional exclusion criteria are set.
You may qualify if:
- The clinical diagnosis is acute ischemic stroke with large- or medium- vessel occlusion (the criteria followed the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018)
- Informed consent from the patient or surrogate
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Xuanwu Hospital, Capital Medical University
Beijing, Beijing Municipality, 100053, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 90 Days
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director of Neurology Department
Study Record Dates
First Submitted
March 7, 2023
First Posted
March 22, 2023
Study Start
April 25, 2023
Primary Completion (Estimated)
April 30, 2032
Study Completion (Estimated)
December 30, 2032
Last Updated
May 30, 2024
Record last verified: 2024-05
Data Sharing
- IPD Sharing
- Will not share