Registration of Acute Ischemic Stroke With Large and Medium-sized Vascular Occlusion in Southwest China(LMVOS)
LMVOS
1 other identifier
observational
8,000
1 country
1
Brief Summary
This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2023
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 6, 2023
CompletedFirst Posted
Study publicly available on registry
November 9, 2023
CompletedStudy Start
First participant enrolled
November 9, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2045
ExpectedStudy Completion
Last participant's last visit for all outcomes
May 1, 2046
November 13, 2023
November 1, 2023
22.1 years
November 6, 2023
November 9, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
modified Rankin Scale (mRS) score
Ordinal distribution of mRS at 90±7 days; modified Rankin scale (range, 0 to 6, with a score of 0 indicating no disability, 1 no clinically significant disability, 2 slight disability, 3 moderate disability but remaining able to walk unassisted, 4 moderately severe disability, 5 severe disability, and 6 death)
90±7 days
Secondary Outcomes (11)
Excellent functional outcome
90±7 days
Good functional outcome
90±7 days
mRS 0-3
90±7 days
Change of National Institutes of Health Stroke Scale (NIHSS)
24 hours
Change of National Institutes of Health Stroke Scale (NIHSS)
7 days
- +6 more secondary outcomes
Other Outcomes (5)
Incidence of clinically significant intracranial hemorrhage
36 hours
Incidence of any intracranial hemorrhage
36 hours
All-cause mortality
90±7 days
- +2 more other outcomes
Study Arms (1)
Acute ischemic stroke with large- or medium-vessel occlusion
Acute ischemic stroke patients with large- or medium-vessel occlusion including all treatments.
Interventions
Visits at 90±7 days after stroke onset were conducted by trained and blinded investigators, with face-to-face, telephone call or Internet access.
Eligibility Criteria
Patients with acute ischemic stroke due to large- or medium-vessel occlusion will be enrolled and no additional exclusion criteria are set.
You may qualify if:
- The clinical diagnosis is acute ischemic stroke with large- or medium- vessel occlusion (the criteria followed the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018).
- Informed consent from the patient or surrogate.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Zhengzhou Yuanlead
Study Sites (1)
Affiliated Hospital of Southwest Medical University
Luzhou, 646000, China
Biospecimen
Blood and Thrombosis.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Zhengzhou Yuan, MD
Department of Neurology, Affiliated Hospital of Southwest Medical University, LuZhou, China.
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Deputy Director of Stroke Center
Study Record Dates
First Submitted
November 6, 2023
First Posted
November 9, 2023
Study Start
November 9, 2023
Primary Completion (Estimated)
December 1, 2045
Study Completion (Estimated)
May 1, 2046
Last Updated
November 13, 2023
Record last verified: 2023-11
Data Sharing
- IPD Sharing
- Will not share