NCT05772988

Brief Summary

This study will randomize CrossFit participants to receive beta-alanine or placebo supplementation for 3 weeks. The study will be double-blind. Performance on the "Fran" test will be completed at baseline and after the 3 week intervention. Respiratory exchange ratio will also be assessed during the performance test at baseline and after 3 weeks.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 4, 2023

Completed
11 days until next milestone

Study Start

First participant enrolled

March 15, 2023

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 17, 2023

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2023

Completed
Last Updated

May 29, 2024

Status Verified

May 1, 2024

Enrollment Period

6 months

First QC Date

March 4, 2023

Last Update Submit

May 24, 2024

Conditions

Exercise-Induced Lactic Acidemia

Outcome Measures

Primary Outcomes (1)

  • Change from baseline in time to perform a "Fran" CrossFit workout

    This involves alternating sets of dumbbell thrusters and pull-uips

    Baseline, 3 weeks

Secondary Outcomes (1)

  • Change from baseline in respiratory exchange ratio

    Baseline, 3 weeks

Study Arms (2)

Beta-alanine

EXPERIMENTAL

Beta-alanine to be given for three weeks

Dietary Supplement: Beta-alanine

Maltodextrin

PLACEBO COMPARATOR

Placebo to be given for three weeks

Dietary Supplement: Maltodextrin

Interventions

Beta-alanineDIETARY_SUPPLEMENT

Beta-alanine

Beta-alanine
MaltodextrinDIETARY_SUPPLEMENT

Maltodextrin

Maltodextrin

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Minimum of one year of CrossFit experience and doing CrossFit training at least twice a week

You may not qualify if:

  • Having consumed beta-alanine in the past six months
  • Having changed the dose of any other nutritional supplement within the past month
  • Having suffered a major physical injury in the past six months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Saskatchewan

Saskatoon, Saskatchewan, S7N5B2, Canada

Location

MeSH Terms

Interventions

beta-Alaninemaltodextrin

Intervention Hierarchy (Ancestors)

AlanineAmino AcidsAmino Acids, Peptides, and Proteins

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 4, 2023

First Posted

March 17, 2023

Study Start

March 15, 2023

Primary Completion

August 31, 2023

Study Completion

August 31, 2023

Last Updated

May 29, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will not share

Locations

CA(1)