NCT05770323

Brief Summary

The aim of the study is to acess the association between admission serum uric acid level and in\_hospital outcomes in patients with acute coronary syndromes

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2023

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 22, 2023

Completed
21 days until next milestone

First Posted

Study publicly available on registry

March 15, 2023

Completed
7 days until next milestone

Study Start

First participant enrolled

March 22, 2023

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 22, 2024

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 22, 2024

Completed
Last Updated

March 15, 2023

Status Verified

March 1, 2023

Enrollment Period

11 months

First QC Date

February 22, 2023

Last Update Submit

March 3, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Association between serum uric acid level and acute coronary syndrome in hospital outcomes

    Comparision between Patient with hyperurecemia and those with normal uric acid level

    From the day of admission and 30 days post discharge

Study Arms (2)

Patients with normal uric acid levels

Patient with uric acid level (2.5\_6)for femal and (3\_7)for males

Diagnostic Test: Uric acid level

Patients with elevated uric acid level (hyperurecemia)

Uric acid level more than 7 for males and more than 6 for female

Diagnostic Test: Uric acid level

Interventions

Uric acid levelDIAGNOSTIC_TEST

Uric acid will be measured for all Patients with acute coronary syndrome and result will be analysed

Patients with elevated uric acid level (hyperurecemia)Patients with normal uric acid levels

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All Patient admited to sohag University in CCU with acute coronary syndrome

You may qualify if:

  • all patients with acute coronary syndrome with one of the Following
  • Typical Chest pain
  • ECG changes
  • Elevated cardiac enzyme

You may not qualify if:

  • patients aged less than 18 years
  • patients with gout
  • patients with treated with diuretics
  • Patient with CKD
  • Patient with chronic haemolytic anemia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Maloberti A, Biolcati M, Ruzzenenti G, Giani V, Leidi F, Monticelli M, Algeri M, Scarpellini S, Nava S, Soriano F, Oreglia J, Sacco A, Morici N, Oliva F, Piani F, Borghi C, Giannattasio C. The Role of Uric Acid in Acute and Chronic Coronary Syndromes. J Clin Med. 2021 Oct 16;10(20):4750. doi: 10.3390/jcm10204750.

    PMID: 34682873BACKGROUND

MeSH Terms

Conditions

Acute Coronary Syndrome

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular Diseases

Central Study Contacts

Hassan A Hassanin

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident doctor at sohag University

Study Record Dates

First Submitted

February 22, 2023

First Posted

March 15, 2023

Study Start

March 22, 2023

Primary Completion

February 22, 2024

Study Completion

March 22, 2024

Last Updated

March 15, 2023

Record last verified: 2023-03