Awareness of Osteoporosis in Multiple Sclerosis Patients

NCT05760651 | Completed

• 1 other identifier: OPMS1
• Study Type: observational
• Target: 325
• Locations: 1 country
• Sites: 1

Brief Summary

Osteoporosis is a condition that describes compromised skeletal microarchitecture in general, with clinical signs of decreased bone mineral density. Multiple sclerosis patients are at increased risk for developing osteoporosis. Identifying whether multiple sclerosis patients have information and awareness about this disease is crucial. This study is aimed to investigate awareness and knowledge of osteoporosis in multiple sclerosis (MS) patients. The study also aimed to assess potential differences and correlations in osteoporosis knowledge and awareness among MS patients based on gender, education levels, and risk of falls

Conditions

Multiple Sclerosis; Osteoporosis; Osteoporosis Risk

Outcome Measures

Primary Outcomes (2)

• Revised Osteoporosis Knowledge Test Scores

  The 32-item Revised Osteoporosis Knowledge Test (ROKT; 2012), as reported by Gendler et al. (2015), is a revision of the original 24-item OKT developed by Kim, Horan, \& Gendler (1991). This measure was developed to assess the osteoporosis knowledge of adults. Changes were made to update the original OKT to include current recommendations for calcium and vitamin D, exercise requirements, diagnosis and treatment, and a more comprehensive understanding of bone development and osteoporosis risk factors. It contains two subscales (Nutrition and Exercise), which share 14 common items including risk factors and general knowledge. Although the responses offered to participants are multiple choice (e.g., for risk items: more likely, less likely, neutral, don't know), there is only one correct answer for each item. Responses are dichotomously recoded as correct or incorrect.

  1 day

• Osteoporosis Awareness Scale Scores

  The OAS, developed by Choi et al. in 2008, includes 31 items across 5 sub-dimensions, rated on a 4-point Likert scale. Validity and reliability assessment in Turkish was made by Aktürk et al. . The potential scores on the OAS range from a minimum of 31 to a maximum of 124. The overall osteoporosis awareness level is reflected in the mean score obtained from the entire scale, with higher scores indicating greater awareness. It's worth noting that the OAS doesn't include items with reverse scoring, and it lacks a specific cut-off point for interpretation.

  1 day

Secondary Outcomes (1)

• Correlation between the level of knowledge and awareness regarding osteoporosis with gender, education levels, and fall risks

  1 day

Study Arms (1)

Multiple Sclerosis Patients

Patients diagnosed with multiple sclerosis.

Other: Patient Participation Form; Diagnostic Test: Timed up - and - go test

Interventions

Patient Participation Form OTHER

A form that consists of revised osteoporosis knowledge test and osteoporosis awareness scale

Multiple Sclerosis Patients

Timed up - and - go test DIAGNOSTIC_TEST

. The timed up-and-go test involves rising from a seated position, walking a distance of 3 meters, pivoting, returning to the initial point, and resuming a sitting position. It demonstrates strong inter-rater and intra-rater reliability, offering a reliable means of quantifying functional mobility and balance.

Multiple Sclerosis Patients

Eligibility Criteria

• Age: 18 Years - 99 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients aged 18 to 90 years with a diagnosis of multiple sclerosis who gave consent to participate in the study

You may qualify if:

• Clinical diagnosis of multiple sclerosis
• Must be between the ages of 18 and 99
• Must give consent to participate in the study

You may not qualify if:

• Not giving consent

Sponsors & Collaborators

• Uskudar State Hospital: lead

Study Sites (1)

Sancaktepe Şehit Doktor İlhan Varank Training and Research Hospital

Istanbul, Sancaktepe, Turkey (Türkiye)

Location

Related Publications (1)

• Temel MH, Tasdelen B, Demir S, Ata E. Assessing osteoporosis awareness and knowledge levels of Turkish multiple sclerosis patients: an observational study. Arch Osteoporos. 2024 Aug 1;19(1):67. doi: 10.1007/s11657-024-01426-y.

  PMID: 39085698 DERIVED

MeSH Terms

Conditions

Multiple Sclerosis; Osteoporosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Bone Diseases, Metabolic; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Mustafa H Temel, M.D.

  Uskudar State Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 25, 2023
• First Posted: March 8, 2023
• Study Start: October 10, 2023
• Primary Completion: December 1, 2023
• Study Completion: December 10, 2023
• Last Updated: April 26, 2024

Record last verified: 2024-04

Locations

TU (1)