The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section

NCT05758233 | Completed

• 1 other identifier: 2022-74
• Study Type: interventional
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section under spinal anesthesia. The main question\[s\] it aims to answer are: \[Is transversalis fascia plane block more effective in postoperative analgesia? \] \[Is there a difference between the duration of postoperative first analgesia requirement? \] Since the pain scores after the block at the end of the operation will be evaluated during the postoperative 24 hours, the participants will be asked to give a value between 0 and 10 in certain time periods.

Conditions

Anesthesia; Sexual; Analgesia

Keywords

anesthesia recovery period; cesarean section; obstetric anesthesia; spinal anaesthesia; postoperative analgesia

Outcome Measures

Primary Outcomes (1)

• time of first analgesic need

  Our primary goal was to meet the initial analgesic requirement times.

  24 hours postoperatively

Secondary Outcomes (1)

• visuel analog scale

  24 hours postoperatively

Study Arms (2)

Grup 1: Transversalis Fascia Plane Block (TFPB)

EXPERIMENTAL

Transversalis Fascia Plane Block (TFPB)

Procedure: Patients undergoing transversalis fascia plane block; Procedure: Patients undergoing transversus abdominis plane block

Grup 2: Transversus Abdominis Plane Block (TAPB)

EXPERIMENTAL

Transversus Abdominis Plane Block (TAPB)

Procedure: Patients undergoing transversalis fascia plane block; Procedure: Patients undergoing transversus abdominis plane block

Interventions

Patients undergoing transversalis fascia plane block PROCEDURE

The investigators applied a transversalis fascia plane block to the group of patients who had a cesarean section under spinal anesthesia to prevent postoperative pain.

Grup 1: Transversalis Fascia Plane Block (TFPB); Grup 2: Transversus Abdominis Plane Block (TAPB)

Patients undergoing transversus abdominis plane block PROCEDURE

The investigators applied a transversus abdominis plane block to the group of patients who had a cesarean section under spinal anesthesia to prevent postoperative pain.

Grup 1: Transversalis Fascia Plane Block (TFPB); Grup 2: Transversus Abdominis Plane Block (TAPB)

Eligibility Criteria

• Age: 20 Years - 50 Years
• Gender Eligibility Details: 20-50 age
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• years old pregnant woman
• ASAII-III
• Patients accepting spinal anesthesia

You may not qualify if:

• Morbid obesity(BMI \>40)
• Patients who are switched to general anesthesia in an unexpected perioperative situation
• Patients with placental anomaly
• Patients with bupivacaine allergy
• Fetal distress situations too urgent to wait for spinal anesthesia and patients who do not want spinal anesthesia

Sponsors & Collaborators

• Bakirkoy Dr. Sadi Konuk Research and Training Hospital: lead

Study Sites (1)

Başakşehir Çam and Sakura City Hospital

Istanbul, Basaksehir, 3268, Turkey (Türkiye)

Location

Related Publications (2)

• Ryu C, Choi GJ, Jung YH, Baek CW, Cho CK, Kang H. Postoperative Analgesic Effectiveness of Peripheral Nerve Blocks in Cesarean Delivery: A Systematic Review and Network Meta-Analysis. J Pers Med. 2022 Apr 14;12(4):634. doi: 10.3390/jpm12040634.

  PMID: 35455750 BACKGROUND

• Mitchell KD, Smith CT, Mechling C, Wessel CB, Orebaugh S, Lim G. A review of peripheral nerve blocks for cesarean delivery analgesia. Reg Anesth Pain Med. 2019 Oct 25:rapm-2019-100752. doi: 10.1136/rapm-2019-100752. Online ahead of print.

  PMID: 31653797 RESULT

MeSH Terms

Conditions

Coitus; Agnosia

Condition Hierarchy (Ancestors)

Sexual Behavior; Behavior; Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Duygu Akyol, M.D

  Başakşehir Çam & Sakura City Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: prospective randomize study
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Prospective randomize study

Study Record Dates

• First Submitted: February 20, 2023
• First Posted: March 7, 2023
• Study Start: January 4, 2022
• Primary Completion: June 30, 2022
• Study Completion: June 30, 2022
• Last Updated: July 17, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)