Low-Level Laser Effects on Orthodontic Tooth Movement of Periodontally Compromised Patients.

NCT05739838 | Unknown

• 1 other identifier: ORTHO-108-6-J
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

To investigate the effect of Low Level Laser therapy on orthodontic tooth movement of periodontally compromised patients by evaluating the rate of orthodontic tooth movement and the level of Osteocalcin in the gingival crevicular fluid.

Conditions

Periodontal Diseases; Cancer Metastatic; Orthodontic Tooth Movement

Keywords

Rate of orthodontic tooth movement; Osteiocalsine

Outcome Measures

Primary Outcomes (1)

• Rate of orthodontic tooth movement

  Rate of mandibular canine retraction

  6 months

Secondary Outcomes (1)

• Osteocalcin level in GCF

  6 months

Study Arms (2)

Periodontally compromised patients subjected to low level laser therapy

EXPERIMENTAL

periodontally compromised patients with pocket depth of more than 5 mm before receiving nonsurgical periodontal treatment treatment or/and pocket depth of less than 4 mm with periodontal status identified as stable for at least 3 month after nonsurgical periodontal treatment subjected to low-level laser of 940 nm will be applied at day one after start of treatment , weekly during the first month, then monthly.

Device: Biolase ;Low Level Laser

Periodontally compromised patients

NO INTERVENTION

periodontally compromised patients with pocket depth of more than 5 mm before receiving nonsurgical periodontal treatment treatment or/and pocket depth of less than 4 mm with periodontal status identified as stable for at least 3 month after nonsurgical periodontal treatment.

Interventions

Biolase ;Low Level Laser DEVICE

Low Level laser ,940 nm

Also known as: Biolase

Periodontally compromised patients subjected to low level laser therapy

Eligibility Criteria

• Age: 25 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• No systemic disease.
• No history medication (antibiotics and/or anti inflammatory) in the previous 4 months.
• Self motivated patients with acceptable oral hygien.

You may not qualify if:

• Previous orthodontic treatment
• Aggressive periodontitis
• Smokers
• pregnant patients

Sponsors & Collaborators

• Faculty of Dental Medicine for Girls: lead

Study Sites (1)

Faculty of dental medicine for Girls, AL Azhar University

Cairo, 002, Egypt

Location

Related Publications (1)

• Ren C, McGrath C, Gu M, Jin L, Zhang C, Sum FHKMH, Wong KWF, Chau ACM, Yang Y. Low-level laser-aided orthodontic treatment of periodontally compromised patients: a randomised controlled trial. Lasers Med Sci. 2020 Apr;35(3):729-739. doi: 10.1007/s10103-019-02923-0. Epub 2019 Dec 12.

  PMID: 31833004 BACKGROUND

MeSH Terms

Conditions

Periodontal Diseases; Neoplasm Metastasis

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases; Neoplastic Processes; Neoplasms; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Mohsena A Abdelrazek, Lecturer

  Lecturer of Orthodontic department faculty of Dental medicine for Girls AL-azhar University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Model Details: ten patients with periodontally affected teeth subjected to low level laser therapy

Study Record Dates

• First Submitted: February 13, 2023
• First Posted: February 22, 2023
• Study Start: April 1, 2021
• Primary Completion: April 1, 2023
• Study Completion: May 1, 2023
• Last Updated: February 24, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)