The Effect of Chia Seeds on HDL Cholesterol

NCT05734170 | Completed

• 1 other identifier: 2015-011
• Study Type: interventional
• Target: 11
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this clinical trial is to demonstrate the effect of daily consumption of chia seeds, if any, on HDL cholesterol levels and compare this to the effects of oats on HDL levels in adult populations.

Conditions

Diet; Habits

Keywords

HDL; Cholesterol; Chia; Oats

Outcome Measures

Primary Outcomes (1)

• Lipid Panel

  Patients' blood was taken twice with intent to measure the cholesterol profile, including: total triglycerides, LDL cholesterol, and HDL cholesterol.

  1 month

Secondary Outcomes (1)

• Weight

  1 month

Study Arms (3)

Cheerio breakfast

OTHER

Patient consumes 1 serving of cheerios for breakfast every day for 1 month. Blood is drawn to assess lipid panels before diet and after 1 month of diet.

Dietary Supplement: Cheerio Breakfast

Instant Oatmeal Breakfast

OTHER

Patient consumes 1 package instant oatmeal for breakfast each day for 1 month. Blood is drawn to assess lipid panels before diet and after 1 month of diet.

Dietary Supplement: Instant Oatmeal breakfast

Chia Seeds and Instant Oatmeal breakfast.

EXPERIMENTAL

Patient consumes 1 package instant oatmeal with 2 tbsp chia seeds everyday for breakfast for 1 month. Blood is drawn to assess lipid panels before diet and after 1 month of diet.

Dietary Supplement: Chia Seeds and instant oatmeal breakfast

Interventions

Chia Seeds and instant oatmeal breakfast DIETARY_SUPPLEMENT

The final group was to consume one packet of instant oatmeal with two tablespoons of chia seeds mixed in with oatmeal for breakfast for 30 days.

Chia Seeds and Instant Oatmeal breakfast.

Cheerio Breakfast DIETARY_SUPPLEMENT

Patients were instructed to consume one serving of Cheerios according to package instructions each morning for 30 days.

Cheerio breakfast

Instant Oatmeal breakfast DIETARY_SUPPLEMENT

The second group was assigned to consume one packet of instant oatmeal for 30 days.

Instant Oatmeal Breakfast

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Must be able to give voluntary consent
• Must be greater than or equal to 18 years old
• Must be willing to give blood twice
• Must be able to eat assigned breakfast

You may not qualify if:

• "Subjects between the ages of 18 and 50 years old without a history of food allergies to either chia seeds or oats, kidney stones or a history of hyperlipidemia or treatment for hyperlipidemia will be eligible."

Sponsors & Collaborators

• Edward Via Virginia College of Osteopathic Medicine: lead

Related Links

• The promising future of chia, Salvia hispanica L
• Dietary levels of chia: influence on yolk cholesterol, lipid content and fatty acid composition for two strains of hens
• EFFECT OF CHIA SEED (SALVIA HISPANICA L.) CONSUMPTION ON CARDIOVASCULAR RISK FACTORS IN HUMANS: A SYSTEMATIC REVIEW
• Diet-induced oxalate nephropathy from excessive nut and seed consumption
• A dietary pattern including nopal, chia seed, soy protein, and oat reduces serum triglycerides and glucose intolerance in patients with metabolic syndrome

MeSH Terms

Conditions

Habits

Condition Hierarchy (Ancestors)

Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Discipline Chair for Family Medicine

Model Details: This pilot study was a small, randomized controlled trial at an academic primary care center. Each patient provided voluntary written consent prior to participating in the project. At the beginning of the study, each participant was randomly assigned to the red, white or blue group. They were then assigned a number within that group. The red group was instructed to consume one serving of Cheerios according to package instructions each morning for 30 days, the white group one packet of instant oatmeal, and the blue group one packet of instant oatmeal with two tablespoons of chia seeds. Subjects will be questioned to ensure to contraindications to participation. All other dietary or exercise habits will be maintained to reduce risk of confounding variables.Cholesterol profiles and weight will be measured at the beginning and end of the study.

Study Record Dates

• First Submitted: November 21, 2022
• First Posted: February 17, 2023
• Study Start: July 28, 2015
• Primary Completion: August 27, 2015
• Study Completion: August 27, 2015
• Last Updated: February 17, 2023

Record last verified: 2023-02