Vitamin D Deficiency in Coronary Artery Disease

NCT04651101 | Completed DMC

• 1 other identifier: IR.SUMS.MED.REC.1398.246
• Study Type: observational
• Target: 4,526
• Locations: 1 country
• Sites: 1

Brief Summary

Large population cross sectional study, was conducted between 2018-2020 by attendance of 4526 patients in shiraz, Iran. Patients were undergone selective coronary angiography from radial artery approach by an expert interventional cardiologist. 25-hydroxy vitamin D and Hs-CRP levels were measured for all patients

Conditions

Coronary Disease

Keywords

coronary artery disease; vitamin D deficiency; Hs-CRP

Outcome Measures

Primary Outcomes (2)

• coronary disease

  extent of coronary artery disease in invasive coronary angiography

  2 years

• Hs-CRP

  level of blood Hs-CRP as marker of inflammation

  2 years

Study Arms (2)

vitamin D deficient

those patient with vitamin D level below 30 ng/dl

Diagnostic Test: coronary angiography

non vitamin D deficient

those patient with vitamin D above 30 ng/dl

Diagnostic Test: coronary angiography

Interventions

coronary angiography DIAGNOSTIC_TEST

extent of coronary artery disease in invasive coronary angiography

non vitamin D deficient; vitamin D deficient

Eligibility Criteria

• Age: 51 Years - 75 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

those who referred for coronary angiography with suspicion to coronary artery disease, who referred to our clinic

You may qualify if:

• patients with suspected coronary artery disease who referred for coronary angiography

You may not qualify if:

• patients with Vitamin D more than 100ng/ml
• parathyroid disorders
• end-stage-renal-disease (ESRD)
• paraneoplastic syndromes
• Patients with more than 10mg/L Hs-CRP

Sponsors & Collaborators

• Shiraz University of Medical Sciences: lead

Study Sites (1)

Professor kojuri cardiology clinic

Shiraz, Outside of the US, 55318, Iran

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

blood

MeSH Terms

Conditions

Coronary Disease; Coronary Artery Disease; Vitamin D Deficiency

Interventions

Coronary Angiography

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Avitaminosis; Deficiency Diseases; Malnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Cardiac Imaging Techniques; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Angiography; Radiography; Diagnostic Techniques, Cardiovascular; Heart Function Tests

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: November 25, 2020
• First Posted: December 3, 2020
• Study Start: March 1, 2019
• Primary Completion: October 12, 2020
• Study Completion: November 1, 2020
• Last Updated: December 7, 2020

Record last verified: 2020-12

Data Sharing

• IPD Sharing: Will not share

Locations

IR (1)