NCT05821504

Brief Summary

The goal of this clinical trial was to compare to different types of high-intensity interval training in young, healthy females. The main questions were: Will changes in body composition differ between the two interventions? Will changes in endurance and muscle performance differ between the two interventions? Participants were randomized to 8 weeks of high-intensity interval training involving body weight, plyometric exercises or cycling only. Researchers compared changes in endurance performance, body composition, and muscle performance to determine if there were differences between groups.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Aug 2018

Shorter than P25 for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2018

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 21, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 21, 2018

Completed
4.3 years until next milestone

First Submitted

Initial submission to the registry

March 14, 2023

Completed
1 month until next milestone

First Posted

Study publicly available on registry

April 20, 2023

Completed
Last Updated

June 13, 2023

Status Verified

June 1, 2023

Enrollment Period

4 months

First QC Date

March 14, 2023

Last Update Submit

June 11, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Muscle composition at baseline

    echo-intensity value derived from ultrasound that indicates the amount of fat infiltration in muscle

    Pre-intervention

  • Muscle composition after 8-week intervention

    echo-intensity value derived from ultrasound that indicates the amount of fat infiltration in muscle

    At week 9

Secondary Outcomes (20)

  • Fat mass at baseline

    Pre-intervention

  • Fat mass after 8-week intervention

    At week 9

  • Group average growth hormone response (concentration at microLiters/Liters) at baseline

    Pre-intervention

  • Group average growth hormone response (concentration at microLiters/Liters) after 8-week intervention

    At week 9

  • Countermovement jump height at baseline

    Pre-intervention

  • +15 more secondary outcomes

Other Outcomes (8)

  • Weekly exercising heart rate

    during 8-week exercise intervention

  • Weekly exercising perceived effort

    during 8-week exercise intervention

  • Calorie consumption at baseline

    Pre-intervention

  • +5 more other outcomes

Study Arms (2)

Plyometric High-Intensity Interval Training

EXPERIMENTAL

This group performed high-intensity interval training consisting of body-weight, plyometric exercises involving jumping.

Behavioral: High-Intensity Interval Training

Cycling High-Intensity Interval Training

EXPERIMENTAL

This group performed high-intensity interval training consisting of cycling exercise.

Behavioral: High-Intensity Interval Training

Interventions

The training intervention is a popular exercise format that consist of alternating brief bouts of high-intensity efforts with bouts of light effort or complete rest.

Cycling High-Intensity Interval TrainingPlyometric High-Intensity Interval Training

Eligibility Criteria

Age18 Years - 35 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Between 18-35 years of age
  • Female
  • Currently participating in 2-4 days of structured exercise for 30-75 minutes for the last 6 months

You may not qualify if:

  • Currently participating in these exercise formats (2x/week within last 3 months)
  • Engaging in high intensity interval training for more than 30 min/week
  • Have diagnosed disorders/diseases in the following: cardiovascular, pulmonary, immunological, or metabolic
  • Current musculoskeletal injuries
  • Pregnant or think you may be pregnant
  • Currently taking any non-steroidal anti-inflammatory drug(s) or steroidal drug(s)
  • Currently a smoker or has consistently smoked within the last year
  • Has a positive written or verbal pre-study drug screen including alcohol (more than 7 drinks/week), THC/cannabinoids, amphetamines, benzodiazepines, cocaine, opioids, phencyclidine, barbiturates, cotinine.
  • Currently taking any medication that will significantly affect your heart rate response to exercise
  • If you miss four or more classes, you will be excluded from the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kennesaw State University

Kennesaw, Georgia, 30144, United States

Location

Related Publications (1)

  • Holmes AJ, Stratton MT, Bailly AR, Gottschall JS, Feito Y, Ha PL, Lavigne A, Persaud K, Gagnon HL, Krueger A, Modjeski A, Esmat TA, Harper LN, VanDusseldorp TA, Hester GM. Effects of plyometric- and cycle-based high-intensity interval training on body composition, aerobic capacity, and muscle function in young females: a field-based group fitness assessment. Appl Physiol Nutr Metab. 2023 Dec 1;48(12):932-945. doi: 10.1139/apnm-2022-0465. Epub 2023 Aug 9.

MeSH Terms

Interventions

High-Intensity Interval Training

Intervention Hierarchy (Ancestors)

Physical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: Two groups performed different types of high-intensity interval training
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor of Exercise Science

Study Record Dates

First Submitted

March 14, 2023

First Posted

April 20, 2023

Study Start

August 1, 2018

Primary Completion

November 21, 2018

Study Completion

November 21, 2018

Last Updated

June 13, 2023

Record last verified: 2023-06

Data Sharing

IPD Sharing
Will not share

There is no plan to share.

Locations