NCT05708872

Brief Summary

In this study, it will be investigated whether the methods of self-regulation of mental state have an effect on postoperative pain perception in colon cancer patients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2022

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2022

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

December 27, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 1, 2023

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
Last Updated

February 1, 2023

Status Verified

December 1, 2022

Enrollment Period

2.2 years

First QC Date

December 27, 2022

Last Update Submit

January 24, 2023

Conditions

Keywords

Colonic NeoplasmsColorectal NeoplasmsColectomyColorectal SurgeryPain, PostoperativeAnalgesicsHypnosisAutosuggestionMind-Body TherapiesHypnotherapyPsychotherapy

Outcome Measures

Primary Outcomes (1)

  • Effect of methods of self-regulation of mental state on postoperative pain perception changes

    The timing of primary outcome measurement includes more than one time point because outcome measurements assess changes in patient status. The patient's condition will be assessed before surgery and at the following post-operative periods: the first day, the fourth day and one month after surgery. The measure will assess the condition over the last 24 hours on scales ranging from -10 to +10 of the Activity Change Scale. For pain, the score will be reviewed by asking: 1\. Which bodily sensations predominate at the site of the illness? A score of -10 indicates maximal relief; 0 neutral condition; and +10 indicates maximal pain. For all answers, higher scores mean a worse outcome.

    The patient's condition will be assessed before surgery and at the following post-operative periods: the first day, the fourth day and one month after surgery.

Secondary Outcomes (2)

  • Effect of methods of self-regulation of mental state on mood changes

    The patient's condition will be assessed before surgery and at the following post-operative periods: the first day, the fourth day and one month after surgery.

  • Effect of methods of self-regulation of mental state on anxiety changes

    The patient's condition will be assessed before surgery and at the following post-operative periods: the first day, the fourth day and one month after surgery.

Study Arms (2)

Study group

EXPERIMENTAL
Behavioral: Autohypnosis

Control group

ACTIVE COMPARATOR
Behavioral: Relaxing music

Interventions

AutohypnosisBEHAVIORAL

Patients in the study group will receive a voice recording with hypnotic instructions with a suggestion to improve the psychophysical state.

Study group
Relaxing musicBEHAVIORAL

Patients in the control group will receive a recording with relaxing music

Control group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Written informed consent to participate in the study
  • Age \>= 18 years
  • Histopathological diagnosis of primary colon cancer without distant metastasis
  • Planned surgical treatment
  • Fluency in Polish

You may not qualify if:

  • Severe comorbidities with pain disorders
  • Regular use of analgesics
  • Coexistence of another neoplastic disease
  • Use of non-pharmacological pain management (including autohypnosis) prior to the study
  • Poor general condition
  • Previous colorectal surgery
  • Hearing disorders
  • No possibility of playback of the received recording

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch

Gliwice, 44-102, Poland

RECRUITING

MeSH Terms

Conditions

Colonic NeoplasmsPain, PostoperativeColorectal Neoplasms

Interventions

Hypnosis

Condition Hierarchy (Ancestors)

Intestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesPostoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and SymptomsRectal Diseases

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsPsychotherapyBehavioral Disciplines and Activities

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 27, 2022

First Posted

February 1, 2023

Study Start

October 1, 2022

Primary Completion

December 1, 2024

Study Completion

December 1, 2024

Last Updated

February 1, 2023

Record last verified: 2022-12

Data Sharing

IPD Sharing
Will not share

Locations