NCT05707039

Brief Summary

Patellofemoral pain syndrome (PFPS) is a common source of knee pain in the physically active population, predominantly in women. The incidence rate of PFPS among athletes is 25 percent, which is higher than that of general population. PFPS is caused by repetitive stress and aggravated in athletes by cycling and running. These symptoms are caused by structural or biomechanical changes of the joint, which becomes exacerbated by activities such as going up and down stairs, sit for a prolonged period, squatting or kneeling, resulting in increased compressive forces in the joint patellofemoral. It is characterized by defused pain in front of knee. Other signs also present are the patellar crepitus, swelling, and joint blockage despite being deemed a multifactorial condition with no single cure, PFPS is commonly attributed to muscular dysfunction, for which conservative rehabilitation is the treatment of choice. Historically, PFPS has been linked to impairments of the quadriceps muscle.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2022

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

January 22, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 31, 2023

Completed
1 day until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2023

Completed
Last Updated

January 31, 2023

Status Verified

January 1, 2023

Enrollment Period

1 year

First QC Date

January 22, 2023

Last Update Submit

January 30, 2023

Conditions

Keywords

PFPS, OCKE, CCKE

Outcome Measures

Primary Outcomes (3)

  • NPRS

    Numerical Pain Rating Scale (NPRS) is a subjective measure in which individuals rate their pain on an eleven-point numerical scale.

    6 weeks

  • LEFS

    Lower Extremity Functional Scale (LEFS) is to measure "patients' initial function, ongoing progress, and outcome" for a wide range of lower-extremity conditions.

    6 week

  • Y balance test

    Y Balance test is a dynamic test required for proprioception along with strength and flexibility.

    6 weeks

Study Arms (2)

Open chain kinetic exercises

EXPERIMENTAL

In open chain exercises extremities are free to move and there is no weight bearing. Subjects performed group of exercises, 3sets of 10 repetitions for each exercise after warm-up and stretching exercises The open kinetic chain exercise program consisted of 1) maximal static quadriceps muscle contractions

Other: Open kinetic chain exercises

Closed Chain Kinetic Exercises

EXPERIMENTAL

In closed kinetic chain exercises extremities are fixed and weight bearing is done. Subjects performed group of exercises, 3sets with 10 repetitions for each exercise after warm up and stretching exercises. The closed kinetic chain exercise program consisted of 1) seated leg presses, 2) one-third knee bends on one leg and on both legs, 3) stationary bicycling, 4) rowing-machine exercises, 5) step-up and step-down exercises. Each exercise in the closed kinetic chain protocol was performed dynamically with a 3-second rest between repetitions.

Other: Closed kinetic chain exercises

Interventions

In open chain exercises extremities are free to move and there is no weight bearing.

Open chain kinetic exercises

In closed kinetic chain exercises extremities are fixed and weight bearing is done.

Closed Chain Kinetic Exercises

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Adult athletes with age 18 to 30 years
  • Anterior Knee pain
  • An insidious onset of symptoms not related to trauma.
  • Pain with compression of patella.
  • Pain on palpation of patellar facets.
  • Experienced players (who are in practice from last 8 months or a year).

You may not qualify if:

  • Symptoms present less than 1 month.
  • Intra-articular knee pathologies like O.A, R.A etc
  • History of knee surgery within last year.
  • History of traumatic injuries like patellar dislocations or subluxation
  • Any other lower extremity injuries.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pakistan Sports Board

Lahore, Punjab Province, 5433, Pakistan

RECRUITING

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal Diseases

Study Officials

  • Muhammad Asrar Yousaf, mphil

    Riphah International University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 22, 2023

First Posted

January 31, 2023

Study Start

February 1, 2022

Primary Completion

February 1, 2023

Study Completion

February 1, 2023

Last Updated

January 31, 2023

Record last verified: 2023-01

Data Sharing

IPD Sharing
Will not share

Locations