Effects of Recruitment Manouever on Oxygenation, Oxygen Reserve Index and Postoperative Pulmonary Complications

NCT05705245 | Unknown

• 1 other identifier: 2021/138
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

General anesthesia and mechanical ventilation decrease pulmonar volume; attenuate small airway closure, atelectasis, and increase the rate of hypoxia and postoperative pulmonary complications. Lung volume in obese patients decreases inversely with the increase in body mass index. Obesity is associated with increased atelectasis, hypoxia and postoperative pulmonary complication rates during anesthesia . Alveolar recruitment maneuver is a technique where high positive end-expiratory pressure (PEEP) is applied for for short periods, follwed by a continuous PEEP appşication throughout surgery. This has become a standard practice during anesthesia in recent years. Oxygen reserve index (ORi) is an index measured with a non-invasive finger-tip sensor and shows the oxygen content of the venous blood. It is effective at high oxygen levels and may indicate the presence of hyperoxia. Our aim is to examine the effect of alveolar recruitment maneuver on oxygenation parameters under anesthesia and the correlation with ORi in morbidly obese patients.

Conditions

Obesity; Bariatric Surgery Candidate

Keywords

obesity, bariatric surgery, alveolar recruitment, oxygen reserve index

Outcome Measures

Primary Outcomes (1)

• postoperative pulmonary complications

  Coughing, dyspnoe, side pain, phlegm

  5 days

Secondary Outcomes (1)

• Effect of recruitment manoeuver on oxygene reserve index

  intraoperative

Study Arms (2)

recruitment

Patients who received alveolar recruitment manouever during bariatric surgery

Other: recruitment

non recruitment

patients who did not receive alveolar recruitment manoeuver during bariatric surgery

Interventions

recruitment OTHER

Automated alveolar recruitment menouever applied during mechanical ventilation in the intraoperative period

recruitment

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

obese patients with BMI\> 40 scheduşed for bariatric surgery

You may qualify if:

• Bariatric surgery general anesthesia and mechanical ventilation via orotracheal entubation Age between 18-65 ASA I-III BMI \> 40 m-2

You may not qualify if:

• Previous history of thorasic surgery, pneumothorax Chemo or Radiotherapy to the chest within 2 months History of Respiratory disease (COPD, emphysema, pneumonia, lung malignancy, Lung Bulla ) Emergency surgery Cardiovascular, renal, hepatic, neuromuscular disease İntracrabial pathology or trauma High intraoptic pressure Pulmonary Hypertension Pregnancy Criticall illness, or history of mechanical ventilation within 1 month

Sponsors & Collaborators

• Balikesir University: lead

Study Sites (1)

Balikesir University Hospital

Balıkesir, 10145, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Hafize Fisun Demir

CONTACT

05437838615; fusdemir@yahoo.com

Nazan Kocaoğlu

CONTACT

0 5326664869; nazankocaoglu@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Study Record Dates

• First Submitted: January 20, 2023
• First Posted: January 30, 2023
• Study Start: January 22, 2022
• Primary Completion: January 1, 2024
• Study Completion: July 1, 2024
• Last Updated: January 30, 2023

Record last verified: 2023-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)