NCT05698797

Brief Summary

Patellofemoral pain syndrome (PFPS) is a common musculoskeletal disorder characterized by an insidious onset of pain in the knee's anterior /retro-patellar / peripatellar region. Even though various rehabilitation approaches, including hip strengthening and proprioceptive training, are being considered for managing PFPS, the most appropriate treatment from these two is still unclear. Therefore, this study aimed to compare the program consisting of hip abductors and external rotators strengthening exercises vs. the program consisting of proprioceptive training of the knee to identify the most effective rehabilitation approach for patients suffering from PFPS.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 11, 2021

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 6, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 24, 2022

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

January 16, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

January 26, 2023

Completed
Last Updated

January 26, 2023

Status Verified

January 1, 2023

Enrollment Period

6 months

First QC Date

January 16, 2023

Last Update Submit

January 16, 2023

Conditions

Keywords

Hip muscles strengtheningRehabilitationProprioceptive trainingExercises

Outcome Measures

Primary Outcomes (1)

  • Kujala Anterior Knee Pain Scale (AKPS)

    Pain was measured using the AKPS. The AKPS is scored from a minimum score of 0 to a maximum score of 100 points. Lower scores indicate greater pain and disability.

    4 weeks.

Study Arms (3)

Experimental group 1

EXPERIMENTAL

In this group participants received hip abductor and external rotator strengthening exercises in addition to conventional physical therapy.

Other: Hip strengthening exercises

Experimental group 2

ACTIVE COMPARATOR

In this group participants received proprioceptive training and conventional physical therapy.

Other: Proprioceptive training

Control group

ACTIVE COMPARATOR

In this group participants received conventional physical therapy alone.

Other: Conventional physical therapy

Interventions

Hip abductor and external rotator strengthening exercises were performed for 4 weeks.

Experimental group 1

Proprioceptive training consisted of eight exercises was performed for 4 weeks.

Experimental group 2

Conventional physical therapy included interferential therapy and two types of knee-strengthening exercises.

Control group

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age 18-35 years
  • Patients diagnosed recently by an orthopedic surgeon for Patello-femoral pain syndrome
  • experiencing anterior/retro patellar knee pain during activities,
  • insidious onset of symptoms not linked to trauma,
  • pain persisting for no less than four weeks,
  • pain on palpation of the patellar facets,
  • pain when stepping down from a 25-cm step or during a double-legged squat.

You may not qualify if:

  • Patients with recent lower limb fractures or dislocations,
  • knee/hip joint surgery,
  • signs, symptoms, or radiological findings of intra-articular pathology such as effusion, ligamentous or meniscal involvement,
  • those with indications of patellar apprehension,
  • referred pain from the hip, back, or sacroiliac joint,
  • acute knee strain or sprain,
  • on medication such as NSAIDs or corticosteroids,
  • degenerative and infectious arthritis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

King Saud University

Riyadh, 11433, Saudi Arabia

Location

Related Publications (1)

  • Raju A, Jayaraman K, Nuhmani S, Sebastian S, Khan M, Alghadir AH. Effects of hip abductor with external rotator strengthening versus proprioceptive training on pain and functions in patients with patellofemoral pain syndrome: A randomized controlled trial. Medicine (Baltimore). 2024 Feb 16;103(7):e37102. doi: 10.1097/MD.0000000000037102.

MeSH Terms

Conditions

Patellofemoral Pain SyndromeMotor Activity

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal DiseasesBehavior

Study Officials

  • Masood Khan, M.P.Th

    King Saud University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 16, 2023

First Posted

January 26, 2023

Study Start

November 11, 2021

Primary Completion

May 6, 2022

Study Completion

June 24, 2022

Last Updated

January 26, 2023

Record last verified: 2023-01

Data Sharing

IPD Sharing
Will not share

Locations