SMCV Assessment on Brain Swelling in Patients With SAH

NCT05696639 | Unknown DMC

• 1 other identifier: BYL20220216
• Study Type: observational
• Target: 198
• Locations: 1 country
• Sites: 1

Brief Summary

Cerebral swelling is a major complication following aneurysmal subarachnoid hemorrhage.This study is a retrospective cohort aimed to predict the extent of brain swelling. Cerebral venous assessment can identify the risk of brain swelling and improve surgical outcomes.

Conditions

Aneurysm; Subarachnoid Hemorrhage; Brain Swelling

Outcome Measures

Primary Outcomes (1)

• brain swelling

  grading of brain swelling

  2 weeks

Study Arms (2)

Undeveloped venous group

patients with undeveloped cerebral venous

Procedure: Aneurysm embolization

Well Developed venous group

patients with well-developed cerebral venous

Procedure: Aneurysm embolization

Interventions

Aneurysm embolization PROCEDURE

All patients underwent Aneurysm embolization surgery, the cerebral venous will be observed intraoperatively.

Undeveloped venous group; Well Developed venous group

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with an anterior communicating aneurysmal subarachnoid hemorrhage between January 2017 and December 2022 who underwent aneurysm embolization surgery, excluding patients with posterior communicating aneurysm, poor general condition or combined with pregnancy , malignant tumors.

You may qualify if:

• patients with anterior communicating aneurysm

You may not qualify if:

• Hunt-Hess grade I- patients with posterior communicating aneurysm, poor general condition or combined with pregnancy , malignant tumors were excluded.

Sponsors & Collaborators

• Shenzhen Baoan District People's Hospital: lead

Study Sites (1)

Shenzhen Baoan People's Hospital

Shenzhen, Guangdong, 518000, China

Location

Related Publications (1)

• Zhang Y, Hu J. Effects of low-dose intravenous heparin therapy in aneurysmal subarachnoid hemorrhage: a randomized controlled clinical trial protocol. Trials. 2023 Jul 8;24(1):447. doi: 10.1186/s13063-023-07493-9.

  PMID: 37422666 DERIVED

MeSH Terms

Conditions

Aneurysm; Subarachnoid Hemorrhage; Brain Edema

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Intracranial Hemorrhages; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Hemorrhage; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• JIangang Hu, Phd

  The People Hospital of Shenzhen Baoan

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 13, 2023
• First Posted: January 25, 2023
• Study Start: April 1, 2017
• Primary Completion: December 1, 2022
• Study Completion: December 30, 2023
• Last Updated: January 25, 2023

Record last verified: 2023-01

Locations

CN (1)