Triglyceride-Glucose Index In Heart Failure Patients In Sohag University Hospital

NCT05663632 | Unknown

• 1 other identifier: Soh-Med-22-12-04
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

study the relationship between Triglyceride glucose index and heart failure patients

Conditions

Heart Failure; Insulin Resistance

Keywords

heart failure; triglyceride-glucose index

Outcome Measures

Primary Outcomes (1)

• Triglyceride-Glucose Index in Heart Failure Patients

  identify the relationship between Triglyceride-Glucose Index and heart failure patients in Sohag University hospital

  6 months

Study Arms (2)

group 1 heart failure patients

Group 2 controle

Eligibility Criteria

• Age: 19 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients will be divided into2 groups, as following: Group (1) Heart Failure patients (100 patients) Group (2) control group(100 person) All groups will be subjected to : 1. Complete history taking with special emphasis on Age ,Sex, Smoking, Diabetes mellitus and Hypertension. 2. A thorough clinical examination will stress on: 1- Heart rate (b.p.m.). 2-Systolic BP (mmHg). 3-BMI calculated as the ( weight (kg)/height (m)2). 3-The following investigations will be done to every subject: 1. FBG (mg/dL) 2. FTG, (mg/dL) 3. Total cholesterol (TC) (mg/dL) 4. SCr (mg/dL) 5. Echocardiography TyG index is calculated as ln \[fasting triglyceride (mg/dL) \* fasting glucose (mg/dL) / 2\]

You may qualify if:

• All Heart Failure patients attend to sohag university hospital aged above 18 year old .

You may not qualify if:

• Patients on lipid lowering medications
• Patients on antidiabetic drugs
• Patients with comorbidities eg liver cirrhosis or malignancy

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University Hospital

Sohag, Egypt

RECRUITING

Related Publications (4)

• GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020 Oct 17;396(10258):1204-1222. doi: 10.1016/S0140-6736(20)30925-9.

  PMID: 33069326 BACKGROUND

• Davison B, Cotter G. Why is heart failure so important in the 21st century? Eur J Heart Fail. 2015 Feb;17(2):122-4. doi: 10.1002/ejhf.219. Epub 2014 Dec 30. No abstract available.

  PMID: 25557121 BACKGROUND

• Miller M, Seidler A, Moalemi A, Pearson TA. Normal triglyceride levels and coronary artery disease events: the Baltimore Coronary Observational Long-Term Study. J Am Coll Cardiol. 1998 May;31(6):1252-7. doi: 10.1016/s0735-1097(98)00083-7.

  PMID: 9581716 BACKGROUND

• Shaye K, Amir T, Shlomo S, Yechezkel S. Fasting glucose levels within the high normal range predict cardiovascular outcome. Am Heart J. 2012 Jul;164(1):111-6. doi: 10.1016/j.ahj.2012.03.023.

  PMID: 22795290 BACKGROUND

MeSH Terms

Conditions

Heart Failure; Insulin Resistance

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Central Study Contacts

Aliaa k Khyry, resident doctor

CONTACT

01067655291; aliaakhairy@med.sohag.edu.eg

Ali T Taha, professor

CONTACT

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident at internal medicine department

Study Record Dates

• First Submitted: December 15, 2022
• First Posted: December 23, 2022
• Study Start: December 12, 2022
• Primary Completion: May 1, 2023
• Study Completion: June 1, 2023
• Last Updated: December 23, 2022

Record last verified: 2022-12

Locations

EG (1)