Validity and Reliability of Lower Extremity Position Test in Patients with Multiple Sclerosis

NCT05663541 | Completed

• 1 other identifier: E-60116787-020-238650
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

Sensory disorders are one of the most important problems in individuals with MS, and these disorders are among the first symptoms of MS. Loss of sense of proprioception is particularly common in patients with MS. Studies show that assessment methods for the quantitative measurement of sensory disorders are lacking. Especially in the clinic, there is no evaluation method that evaluates the sense of proprioception. Therefore, the aim of this study perform the validity and reliability study of the lower extremity position test to evaluate proprioception sense in individuals with MS.

Conditions

Multiple Sclerosis; Sensory Impairments; Proprioceptive Disorders; Validity; Reliability

Outcome Measures

Primary Outcomes (5)

• Sensorial Assessment-1

  Lower Extremity Position test

  through study completion, an average of 1 year

• Sensorial Assessment-2

  Kinesthesia (Inclinometer)

  through study completion, an average of 1 year

• Balance Assessment-1

  Static Balance via single leg stance

  through study completion, an average of 1 year

• Balance Assessment-2

  Dynamic Balance via time up and go

  through study completion, an average of 1 year

• Walking Speed Assessment

  The 10 meter walk test

  through study completion, an average of 1 year

Secondary Outcomes (2)

• Demographic Assessment

  through study completion, an average of 1 year

• Expanded Disability Status Scale (EDSS)

  through study completion, an average of 1 year

Study Arms (1)

Patient with multiple sclerosis

Patient with multiple sclerosis

Diagnostic Test: Lower extremity position test

Interventions

Lower extremity position test DIAGNOSTIC_TEST

Assessing proprioception of the lower extremity of individuals multiple sclerosis

Patient with multiple sclerosis

Eligibility Criteria

• Age: 20 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Multiple sclerosis indivuduals

You may qualify if:

• years old
• EDSS score between 0-5
• Person who has not had an attack in the last 1 month or who is not in the attack period
• Person without systemic disease such as hypertension, heart disease, Diabetes Mellitus, hyperlipidemia, malignancy
• Person who has not undergone surgery that restricts balance function in the lower extremity.
• Person without hip, knee and ankle contracture
• Person who does not have additional neurological disease
• Person who does not use vestibulosupressants or drugs that may cause neuropathy and does not have a history of alcohol use
• To have full cooperation and adaptation to the work
• Individuals who agree to receive treatment will be included in the study.

You may not qualify if:

• Being younger than 20 years old and over 65 years old
• Being in the attack period
• Hip, knee or ankle contracture
• Being greater than EDSS 5
• Having systemic diseases such as hypertension, heart disease, Diabetes Mellitus, hyperlipidemia, malignancy
• Having an additional neurological disease
• Having a vestibulospressant or drug or alcohol use habit that causes neuropathy
• Not cooperating and adapting to the work

Sponsors & Collaborators

• Pamukkale University: lead

Study Sites (1)

Romatem Bursa Fizik Tedavi ve Rehabilitasyon Hastanesi

Bursa, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Multiple Sclerosis; Somatosensory Disorders

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Sensation Disorders; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Investigator

Study Record Dates

• First Submitted: December 15, 2022
• First Posted: December 23, 2022
• Study Start: October 24, 2022
• Primary Completion: May 6, 2023
• Study Completion: July 24, 2023
• Last Updated: December 5, 2024

Record last verified: 2023-12

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)