Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk
2 other identifiers
interventional
752
1 country
1
Brief Summary
This study will test the effectiveness, implementation outcomes, and cost effectiveness of a community-tailored, harm reduction kiosk in reducing HIV, hepatitis C, and overdose risk behavior in rural Appalachia. The proposed project will take place in two counties in Appalachian Kentucky, an epicenter for the intertwined national crises of injection drug use, overdoses, and hepatitis C.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Mar 2023
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 3, 2022
CompletedFirst Posted
Study publicly available on registry
December 20, 2022
CompletedStudy Start
First participant enrolled
March 6, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 31, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
July 31, 2027
May 6, 2026
May 1, 2026
3.4 years
November 3, 2022
May 4, 2026
Conditions
Outcome Measures
Primary Outcomes (3)
Change in syringe coverage for injections
Self-reported number of injections in the past 30 days where a clean syringe was used divided by the total number of injections in the past 30 days
Measured at baseline and then every 6 months up to 5 years
Change in harm reduction program supplied syringe coverage for injections
Number of syringes obtained at the SSP and/or KyOSK in the past 30 days (obtained from card swipe/supply dispensing data)
Measured at baseline and then every 6 months up to 5 years
Change in SSP / KyOSK-provided syringe coverage for injections
Self-reported number of injections in the past 30 days where a clean syringe from the \[KyOSK/SSP\] was used divided by the total number of injections in the past 30 days
Measured at baseline and then every 6 months up to 5 years
Secondary Outcomes (14)
Change in frequency of receptive syringe sharing among participants who inject drugs
Measured at baseline and then every 6 months up to 5 years
Change in frequency of distributive syringe sharing among participants who inject drugs
Measured at baseline and then every 6 months up to 5 years
Change in number of people with whom person shared syringes and injection equipment
Measured at baseline and then every 6 months up to 5 years
Change in frequency of syringe reuse among participants who inject drugs
Measured at baseline and then every 6 months up to 5 years
Change in frequency of safe syringe disposal among participants who inject drugs
Measured at baseline and then every 6 months up to 5 years
- +9 more secondary outcomes
Study Arms (2)
Syringe Service Program Plus a Harm Reduction Kiosk Intervention
EXPERIMENTALThe intervention to be implemented in the intervention county involves enhancing its existing SSP model with a KyOSK. The intervention county SSP operates identically to the comparison county. As in the comparison county, a card reader will be installed in the intervention county SSP at the beginning of the study to provide objective data on visits and supply access. The KyOSK will resemble a vending machine. The KyOSK will include harm reduction, wound care, hygiene, and other supplies; offer overdose education and other content; a sharps container with a device to obtain data on syringe disposal; and an innovative call-back feature for care navigation by recovery coaches. While the KyOSK is operating, the intervention county will operate its traditional SSP 40 hours/week.
Syringe Service Program
NO INTERVENTIONThe comparison county SSP operates in the local health department and provides syringes, cookers/cottons, naloxone, wound care kits, condoms and lubricant, snacks, drinks, and sharps containers. A peer support specialist is present for consultation with clients upon request during SSP hours. The SSP will expand it hours from 3 hours/week to 40 hours/week at the same time the intervention county receives its KyOSK, to be comparable. SSP clients who enroll in the study will receive a swipe card linked to their SSP client identification. Card readers will be installed in the SSP for clients to swipe upon entry. Staff will provide clients with the same menu of supplies as those in the KyOSK and the same supply/time interval limits will be imposed. SSP clients will receive a resource guide.
Interventions
The intervention involves enhancing an existing staffed harm reduction program (syringe service program) located in a local health department with a Kentucky Outreach Service Kiosk (KyOSK).
Eligibility Criteria
You may qualify if:
- Individuals are eligible if they are:
- age 18 or older,
- live in the intervention or comparison county, and
- have engaged in injection or non-injection illicit drug use to get high in the past 6 months (excluding marijuana, alcohol, and tobacco).
You may not qualify if:
- being under the age of 18,
- not living in the intervention or comparison county,
- having not engaged in injection or non-injection illicit drug use to get high in the past 6 months (excluding marijuana, alcohol, and tobacco),
- not being able to speak or understand English,
- conviction in the past 10 years of a violent crime (i.e., murder, manslaughter, rape, robbery, and /or aggravated assault) or stalking,
- current charges of violent crime or stalking, or
- having plans to move out of the study counties in the next 6 months, or residing in an inpatient facility.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- April M Younglead
- National Institute on Drug Abuse (NIDA)collaborator
Study Sites (1)
University of Kentucky
Lexington, Kentucky, 40506, United States
Related Publications (2)
Young AM, Jahangir T, Westneat S, Cheatom C, Fallin-Bennett A, Fanucchi LC, Freeman PR, Havens JR, Knudsen HK, McCollister KE, Stitzer S, Stone J, Vickerman P, Livingston MD. Preferences for harm reduction vending machine design among rural people who use drugs. Drug Alcohol Depend Rep. 2025 Oct 31;17:100391. doi: 10.1016/j.dadr.2025.100391. eCollection 2025 Dec.
PMID: 41322680DERIVEDYoung AM, Havens JR, Cooper HLF, Fallin-Bennett A, Fanucchi L, Freeman PR, Knudsen H, Livingston MD, McCollister KE, Stone J, Vickerman P, Freeman E, Jahangir T, Larimore E, White CR, Cheatom C, Community Staff K, Design Team K. Kentucky Outreach Service Kiosk (KyOSK) Study protocol: a community-level, controlled quasi-experimental, type 1 hybrid effectiveness study to assess implementation, effectiveness and cost-effectiveness of a community-tailored harm reduction kiosk on HIV, HCV and overdose risk in rural Appalachia. BMJ Open. 2024 Mar 1;14(3):e083983. doi: 10.1136/bmjopen-2024-083983.
PMID: 38431295DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
April M Young, PhD
University of Kentucky
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
November 3, 2022
First Posted
December 20, 2022
Study Start
March 6, 2023
Primary Completion (Estimated)
July 31, 2026
Study Completion (Estimated)
July 31, 2027
Last Updated
May 6, 2026
Record last verified: 2026-05
Data Sharing
- IPD Sharing
- Will not share