NCT05646069

Brief Summary

This study is designed to provide an evaluation of currently available disposable flexible ureteroscopes in real-world conditions. Due to high re-processing costs associated with re-usable flexible ureteroscopes, there has been a demand for Urologic device manufacturers to provide single-use flexible ureteroscopes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 15, 2022

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

November 18, 2022

Completed
24 days until next milestone

First Posted

Study publicly available on registry

December 12, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 5, 2023

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
Last Updated

June 27, 2024

Status Verified

June 1, 2024

Enrollment Period

6 months

First QC Date

November 18, 2022

Last Update Submit

June 26, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Scope performance

    Difference in scope performance grading by multiple blinded reviewers

    0-1 day

Secondary Outcomes (13)

  • Operating room outcomes

    0-1 day

  • Operating room outcomes

    0-1 day

  • Operating room outcomes

    0-1 day

  • Operating room outcomes

    0-1 day

  • Operating room outcomes

    0-1 day

  • +8 more secondary outcomes

Study Arms (3)

Storz Flex-XC1 disposable flexible ureteroscope

EXPERIMENTAL

A patient is randomized to the experimental arm using the Storz Flex-XC1 disposable flexible ureteroscope.

Device: Storz Flex-XC1 Disposable Flexible Ureteroscope

Analogue scope

NO INTERVENTION

A patient is not randomized to the experimental arm using the Storz Flex-XC1 disposable flexible ureteroscope.

Digital ureteroscope

EXPERIMENTAL

A patient is randomized to the experimental arm using a Digital ureteroscope.

Device: Storz Flexible Digital Ureteroscope

Interventions

Patients will receive flexible ureteroscopy with the Storz Flex-XC1 disposable flexible ureteroscope.

Storz Flex-XC1 disposable flexible ureteroscope

Patients will receive flexible ureteroscopy with the Storz flexible Digital ureteroscope.

Digital ureteroscope

Eligibility Criteria

Age18 Years - 89 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Males and Females 18-89 undergoing ureteroscopy for laser treatment of renal calculi
  • Willing to sign the Informed Consent Form
  • Able to read, understand, and complete patient questionnaires, pain texts, and medication diary.

You may not qualify if:

  • Patients having a concomitant procedure along with ureteroscopy (example: contralateral PCNL)
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Northwestern University

Chicago, Illinois, 60611, United States

Location

Related Publications (1)

  • Wong C, Xu P, Dean N, Assmus M, McDonald A, Agarwal D, Ali S, Abedi G, Margolin E, Medairos R, Nottingham C, Krambeck A. A prospective survey evaluating the visual quality of KARL STORZ fiberoptic, digital, and disposable flexible ureteroscopes. World J Urol. 2025 Feb 12;43(1):119. doi: 10.1007/s00345-025-05502-x.

MeSH Terms

Conditions

Kidney Calculi

Condition Hierarchy (Ancestors)

NephrolithiasisKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesUrolithiasisUrinary CalculiMale Urogenital DiseasesCalculiPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
DEVICE FEASIBILITY
Intervention Model
PARALLEL
Model Details: Assignment
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Urology

Study Record Dates

First Submitted

November 18, 2022

First Posted

December 12, 2022

Study Start

November 15, 2022

Primary Completion

May 5, 2023

Study Completion

December 31, 2023

Last Updated

June 27, 2024

Record last verified: 2024-06

Locations