Cerebrospinal Fluid Gravity Correlation Analysis
Correlation Between Blood Biochemical Indicators and Cerebrospinal Fluid Gravity in Aged Patients
1 other identifier
observational
80
1 country
1
Brief Summary
The purpose of this study was to measure cerebrospinal fluid density in aged patients and to see if there was a correlation between these factors and cerebrospinal fluid density by using the electronic medical record system to understand the patient's gender, blood glucose, blood biochemical electrolytes and blood levels.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Dec 2022
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 1, 2022
CompletedStudy Start
First participant enrolled
December 1, 2022
CompletedFirst Posted
Study publicly available on registry
December 9, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 31, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
May 31, 2023
CompletedDecember 9, 2022
November 1, 2022
6 months
December 1, 2022
December 8, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Cerebrospinal fluid density
After obtaining the mass of cerebrospinal fluid, the density was calculated from ρ=m/v
baseline (before anesthesia)
Secondary Outcomes (7)
Blood sugar
baseline (before anesthesia)
Plasma K+ concentration
baseline (before anesthesia)
Plasma Cl- concentration
baseline (before anesthesia)
WBC
baseline (before anesthesia)
Neutrophil concentration in blood
baseline (before anesthesia)
- +2 more secondary outcomes
Study Arms (4)
Group A
Patients were aged 60-69 years
Group B
Patients were aged 70-79 years
Group C
Patients were aged 80-89 years
Group D
Patient age \> 90 years
Interventions
After obtaining the patient's cerebrospinal fluid specimen, the actual mass of the cerebrospinal fluid was measured by pipetting 1000 μL of cerebrospinal fluid specimen on an analytical balance using a pipette gun, and all specimens were measured three times and the average of the three times was taken as the final mass of 1000 μL of that specimen. After the mass measurement, the residual cerebrospinal fluid was disposed of as medical waste. The density of each specimen was obtained according to the density to mass conversion formula ρ=m/v.
After obtaining the patient's blood specimens, they were sent to the laboratory for blood routine examination.
After obtaining the patient's blood specimens, they were sent to the laboratory for blood electrolyte examination.
Eligibility Criteria
Selected aged patients who had hip arthroplasty in our hospital between December 2022 and May 2023
You may qualify if:
- Receiving combined spinal and epidural anesthesia or subarachnoid anesthesia ASA Ⅰ or Ⅱ patients No significant neurological pathology No recent history of cerebral infarction No recent history of cerebral hemorrhage No central nervous system inflammation No spinal inflammatory disease No history of spinal surgery Patients who have given pre-operative informed written consent
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Zhiming Zhang
Chenzhou, Hunan, 423000, China
Biospecimen
Cerebrospinal fluid of the patient
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- ECOLOGIC OR COMMUNITY
- Time Perspective
- CROSS SECTIONAL
- Target Duration
- 1 Day
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD, Ph.D
Study Record Dates
First Submitted
December 1, 2022
First Posted
December 9, 2022
Study Start
December 1, 2022
Primary Completion
May 31, 2023
Study Completion
May 31, 2023
Last Updated
December 9, 2022
Record last verified: 2022-11