Study Stopped
Independent Data Monitoring Committee (IDMC) recommendation to stop the study
A Study to Learn How Well the Study Treatment Asundexian Works and How Safe it is Compared to Apixaban to Prevent Stroke or Systemic Embolism in People With Irregular and Often Rapid Heartbeat (Atrial Fibrillation), and at Risk for Stroke
OCEANIC-AF
A Multicenter, International, Randomized, Active Comparator-controlled, Double-blind, Double-dummy, Parallel-group, 2-arm, Phase 3 Study to Compare the Efficacy and Safety of the Oral FXIa Inhibitor Asundexian (BAY 2433334) With Apixaban for the Prevention of Stroke or Systemic Embolism in Male and Female Participants Aged 18 Years and Older With Atrial Fibrillation at Risk for Stroke
3 other identifiers
interventional
14,830
36 countries
1030
Brief Summary
Researchers are looking for a better way to treat people with atrial fibrillation (AF) and prevent stroke or systemic embolism (blood clots travelling through the blood stream to plug another vessel). Atrial fibrillation is a condition of having irregular and often rapid heartbeat. It can lead to the formation of blood clots in the heart which can travel through the blood stream to plug another vessel, and like this lead to serious and life-threatening conditions, such as a stroke. A stroke occurs because the brain tissue beyond the blockage no longer receives nutrients and oxygen so that brain cells die. As strokes arising from atrial fibrillation can involve extensive areas of the brain, it is important to prevent them. Blood clots are formed in a process known as coagulation. Medications are already available to prevent the formation of blood clots. When taken by mouth (orally), they are known as oral anticoagulants (OACs) including apixaban. OACs decrease the risk of the above-mentioned serious and life-threatening conditions. The main side effect of OACs is an increase of the risk of bleeding. The study treatment asundexian is a new type of anticoagulant currently under development to provide further treatment options. Asundexian aims to further improve the standard of care with regard to the risk of bleeding. The main purpose of this study is to collect more data about how well asundexian works to prevent stroke and systemic embolism and how safe it is compared to apixaban in people with atrial fibrillation and at high risk for stroke. To see how well the study treatment asundexian works researchers compare:
- how long asundexian works well and
- how long apixaban works well after the start of the treatment. Working well means that the treatments can prevent the following from happening:
- stroke and/or
- systemic embolism. The study will keep collecting data until a certain number of strokes or embolisms happen in the study. To see how safe asundexian is, the researchers will compare how often major bleedings occur after taking the study treatments asundexian and apixaban, respectively. Major bleedings are bleedings that have a serious or even life-threatening impact on a person's health. The study participants will be randomly (by chance) assigned to 1 of 2 treatment groups, A and B. Dependent on the treatment group, the participants will either take the study treatment asundexian by mouth once a day or apixaban by mouth twice a day for approximately 9 - 33 months. Each participant will be in the study for approximately 9 - 34 months. There will be visits to the study site every 3 to 6 months and up to 7 phone calls. Those participants who do not want or are unable to have visits to the study site may join the study remotely in selected locations. The location name contains the abbreviation - DCT in such cases. During the study, the study team will:
- take blood samples
- do physical examinations
- examine heart health using an electrocardiogram (ECG)
- check vital signs such as blood pressure and heart rate
- do pregnancy tests
- ask the participants questions about their quality of life
- ask the participants questions about how they are feeling and what adverse events they are having. An adverse event is any medical problem that a participant has during a study. Doctors keep track of all adverse events that happen in studies, even if they do not think the adverse events might be related to the study treatments.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_3
Started Dec 2022
Shorter than P25 for phase_3
1030 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 30, 2022
CompletedStudy Start
First participant enrolled
December 5, 2022
CompletedFirst Posted
Study publicly available on registry
December 8, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 31, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
January 31, 2024
CompletedResults Posted
Study results publicly available
December 9, 2024
CompletedDecember 9, 2024
December 1, 2024
1.2 years
November 30, 2022
October 17, 2024
December 4, 2024
Conditions
Outcome Measures
Primary Outcomes (3)
Number of Participants With Composite of Stroke or Systemic Embolism
The assessment was based on the cause-specific hazard ratio (csHR), comparing asundexian with apixaban which is based on time to first event. Stroke was defined as an acute episode of focal or global neurological dysfunction caused by an injury of the brain, spinal cord, or retina as a result of hemorrhage or infarction. Systemic embolism is defined as abrupt vascular insufficiency associated with clinical or radiological evidence of arterial occlusion in the absence of other likely mechanisms (this does not include myocardial infarction, thromboembolism of the pulmonary vasculature or venous thrombosis, e.g. pulmonary embolism or deep venous thrombosis).
Approximately 12 months
Number of Participants With International Society on Thrombosis and Hemostasis (ISTH) Major Bleeding
Assessment based on the (csHR), comparing asundexian with apixaban which is based on time to first event. ISTH Major Bleeding was defined as an event that meets at least one of the below criteria, based on the definition given by the ISTH (Schulman and Kearon 2005): * Fatal bleeding, and/or * Symptomatic bleeding in a critical area or organ (intracranial, intraspinal, intraocular with compromised vision, pericardial, retroperitoneal, intra-articular, or intramuscular with compartment syndrome), and/or * Clinically overt\* bleeding associated with a recent (within 48 hours) decrease in the hemoglobin level of ≥ 2 g/dL (20 g/L; 1.24 mmol/L) compared with the most recent hemoglobin value available before the event, and/or * Clinically overt\* bleeding leading to transfusion of 2 or more units of packed red blood cells or whole blood. * Overt bleeding required the identification of the bleeding location and the hemoglobin drop and/or transfusion needed to be related to the bleeding.
Approximately 12 months
Number of Participants With Composite of Stroke, Systemic Embolism, or ISTH Major Bleeding
The assessment was based on the cause-specific hazard ratio (csHR), comparing asundexian with apixaban which is based on time to first event.
Approximately 12 months
Secondary Outcomes (13)
Number of Participants With Composite of Ischemic Stroke or Systemic Embolism
Approximately 12 months
Number of Participants With All-cause Mortality
Approximately 12 months
Number of Participants With Ischemic Stroke
Approximately 12 months
Number of Participants With Cardiovascular (CV) Death
Approximately 12 months
Number of Participants With Composite of CV Death, Stroke, or Myocardial Infarction (MI)
Approximately 12 months
- +8 more secondary outcomes
Study Arms (2)
Asundexian
EXPERIMENTALParticipants will receive asundexian and apixaban matching placebo.
Apixaban
ACTIVE COMPARATORParticipants will receive apixaban and asundexian matching placebo.
Interventions
Eligibility Criteria
You may qualify if:
- years of age or older
- The patient willing and able to understand the Patient information Sheet and provide written informed consent
- Atrial fibrillation with an indication for indefinite treatment with an oral anticoagulant
- CHA2DS2-VASc score ≥ 3 if male or ≥ 4 if female, OR CHA2DS2-VASc score of 2 if male or 3 if female and at least one of the following enrichment criteria:
- age ≥ 70
- previous stroke, transient ischemic attack, or systemic embolism
- renal dysfunction with eGFR \< 50 ml/min within 14 days prior to randomization
- prior episode of non-traumatic major bleeding
- current single agent antiplatelet therapy planned to continue for at least 6 months after randomization
- ≤ 6 consecutive weeks of treatment with oral anticoagulant prior to randomization.
You may not qualify if:
- Mechanical heart valve prosthesis
- Atrial fibrillation only due to reversible cause.
- Recent ischemic stroke (within 7 days prior to randomization).
- Active non-trivial bleeding; known chronic bleeding disorder ; history of non-traumatic intracranial hemorrhage.
- Known significant liver disease or known hepatic insufficiency classified as Child-Pugh B or C at randomization.
- Estimated glomerular filtration rate (eGFR) \< 25 mL/min/1.73 m2 within 14 days prior to randomization or on dialysis or expected to be started on dialysis within the next 12 months starting from randomization.
- Major surgery during the last 30 days prior to randomization.
- Known allergy, intolerance or hypersensitivity to either of the study interventions.
- Any contraindication for the use of an anticoagulant or listed in the local labelling for apixaban.
- Requirement for chronic anticoagulation for a different indication than AF, e.g. mechanical heart valve or left ventricular cardiac thrombus (atrial thrombus is allowed), or dual antiplatelet therapy (single agent therapy is allowed).
- Treatment with Vitamin K antagonist (VKA) in the 10 days prior to randomization.
- Concomitant use of or anticipated need for:
- daily or near daily (\> 5 days per week) therapy with nonsteroidal anti-inflammatory drugs (NSAIDs) for more than 4 weeks during the study
- herbal or traditional medicine, and / or supplements with known anticoagulant and / or antiplatelet effect
- combined P-glycoprotein (P-gp) and strong cytochrome P450 isoenzyme 3A4 (CYP3A4) inhibitors
- +5 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Bayerlead
Study Sites (1069)
SEC Clinical Research
Dothan, Alabama, 36305, United States
Eastern Shore Research Institute, LLC | Fairhope, AL
Fairhope, Alabama, 36532, United States
Mobile Heart Specialists, PC
Mobile, Alabama, 36608, United States
University of South Alabama Medical Center
Mobile, Alabama, 36617, United States
Arkansas Cardiology | Little Rock
Little Rock, Arkansas, 72205, United States
Valley Clinical Trials, Inc. | Covina, CA
Covina, California, 91723, United States
Science 37
Culver City, California, 90230, United States
University of California, Irvine
Irvine, California, 92697, United States
VA Long Beach Healthcare System
Long Beach, California, 90822, United States
VA Greater Los Angeles Healthcare System | West Los Angeles VA Medical Center - Cardiology Department
Los Angeles, California, 90073-1003, United States
Radin Cardiovascular Medical Group
Newport Beach, California, 92663, United States
Amicis Research Center | Northridge, CA
Northridge, California, 91324, United States
Cottage Health | Santa Barbara Cottage Hospital - Cardiology Department
Santa Barbara, California, 93102, United States
NorthBay Clinical Research, LLC | Santa Rosa, CA
Santa Rosa, California, 95405, United States
The Lundquist Institute | Cardiology Department
Torrance, California, 90502-2004, United States
Harbor - UCLA Medical Center
Torrance, California, 90502, United States
Blue Coast Research Center, LLC
Vista, California, 92081, United States
Interventional Cardiology Medical Group | West Hills, CA
West Hills, California, 91307, United States
University of Colorado Hospital - Cardiology
Aurora, Colorado, 80045, United States
South Denver Cardiology Associates, PC
Littleton, Colorado, 80120, United States
Cardiology Associates of Fairfield County, P.C. | Stamford, CT
Norwalk, Connecticut, 06851, United States
Integrity Clinical Research | Florida Premier Cardiology
Boynton Beach, Florida, 33437, United States
Integrity Clinical Research | Cardiology Associates of South Florida
Boynton Beach, Florida, 33472, United States
Cardiovascular & Vein Center of Florida | Bradenton, FL
Bradenton, Florida, 34209, United States
Nova Clinical Research | Brandenton, FL
Bradenton, Florida, 34209, United States
Clearwater Cardiovascular Associates | Clearwater, FL
Clearwater, Florida, 33756, United States
Cardiology Consultants, PA
Daytona Beach, Florida, 32114, United States
Cardiology Associates Research Company
Daytona Beach, Florida, 32117, United States
Integrity Clinical Research | Heller Heart Health
Delray Beach, Florida, 33446, United States
North Florida Foundation For Research And Education | Veterans Benefits Administration
Gainesville, Florida, 32608, United States
Indago Research and Health Center | Hialeah, FL
Hialeah, Florida, 33012, United States
Encore Research Group | Nature Coast Clinical Research - Inverness
Inverness, Florida, 34452, United States
University of Florida - Jacksonville
Jacksonville, Florida, 32209, United States
Heart Vein & Vascular | Longwood, FL
Longwood, Florida, 32779, United States
Life Spring Research | Miami, FL
Miami, Florida, 33130, United States
Southwest Florida Research | Naples, FL
Naples, Florida, 34102-8143, United States
Advanced Research for Health Improvement, LLC | Naples, FL
Naples, Florida, 34102, United States
Cardiology Partners Clinical Research Institute | Palm Beach Gardens Office
Palm Beach Gardens, Florida, 33410, United States
Baptist Heart and Vascular/Cardiology Consultants
Pensacola, Florida, 32503, United States
Peace River Cardiovascular Center | Port Charlotte, FL
Port Charlotte, Florida, 33592, United States
Encore Research Group | St. Johns Center for Clinical Research
Saint Augustine, Florida, 32081, United States
East Coast Institute for Research | St. Augustine, FL
Saint Augustine, Florida, 32086, United States
Cardiovascular Center of Sarasota Foundation for Research and Education | Sarasota, FL
Sarasota, Florida, 34239, United States
Cardiology Partners Clinical Research Institute | Wellington Office
Wellington, Florida, 33449, United States
St. Mary's Medical Center | West Palm Beach - Neurology Department
West Palm Beach, Florida, 33407-2495, United States
Morehouse School of Medicine | Clinical Research Centre
Atlanta, Georgia, 30303-3031, United States
NSC Cardiology | Johns Creek, GA
Cumming, Georgia, 30041, United States
Alta Pharmaceutical Research Center, LLC
Peachtree Corners, Georgia, 30092, United States
Atlanta Heart Specialists, LLC
Tucker, Georgia, 30084, United States
St. Luke's Health System | St. Luke's Clinic - Idaho Cardiology Associates
Meridian, Idaho, 83642, United States
Northwestern University
Chicago, Illinois, 60611, United States
Northshore Medical Center
Glenview, Illinois, 60026, United States
Affinity Health Research Institute | Oak Brook, IL
Oak Brook, Illinois, 60523, United States
Midwest Cardiovascular Research and Education Foundation | Elkhart, IN
Elkhart, Indiana, 46514, United States
Cardiovascular Research of Northwest Indiana, LLC. | Munster, IN
Hammond, Indiana, 46320, United States
IU Health Physicians Cardiology
Indianapolis, Indiana, 46202, United States
Reid Physician Associates | Cardiology Department
Richmond, Indiana, 47374, United States
Accellacare | Ames, IA
Ames, Iowa, 50010, United States
University of Iowa
Iowa City, Iowa, 52242, United States
Kansas Nephrology Physicians, PA
Wichita, Kansas, 67226, United States
Baptist Health Lexington
Lexington, Kentucky, 40503, United States
Baptist Health Medical Group - Louisville Cardiology
Louisville, Kentucky, 40207, United States
Research Integrity, LLC
Owensboro, Kentucky, 42303, United States
Cambridge Medical Trials
Alexandria, Louisiana, 71301, United States
Ochsner Clinic Foundation
Baton Rouge, Louisiana, 70836, United States
Cardiovascular Associates Research, LLC
Covington, Louisiana, 70433, United States
Ochsner Medical Center - New Orleans
New Orleans, Louisiana, 70121, United States
Louisiana Heart Center Research - Slidell
Slidell, Louisiana, 70458, United States
Northeast Cardiology Associates
Bangor, Maine, 04401, United States
MaineHealth Maine Medical Center | Maine Medical Partners Cardiology
Scarborough, Maine, 04039, United States
LifeBridge Health | Sinai Hospital - Platelet and Thrombosis Research Department
Baltimore, Maryland, 21215, United States
Spectrum Clinical Research | Maryland Cardiovascular Specialists
Baltimore, Maryland, 21229, United States
Johns Hopkins Hospital/Health System
Baltimore, Maryland, 21287, United States
Johns Hopkins University School of Medicine | CAPRES
Columbia, Maryland, 21044, United States
Anderson Medical Group and Cardiology | Anderson Medical Research, LLC
Ft. Washington, Maryland, 20744, United States
Adventist HealthCare | White Oak Medical Center
Silver Spring, Maryland, 20904, United States
McLaren Health Care | McLaren Bay Region - Research Department
Bay City, Michigan, 48708, United States
Henry Ford Health System
Detroit, Michigan, 48202, United States
AA Medical Research Center | Flint, MI
Flint, Michigan, 48504, United States
Sparrow Clinical Research Institute | Sparrow Hospital - Clinical Research Department
Lansing, Michigan, 48912, United States
M Health Fairview
Maplewood, Minnesota, 55109, United States
Veterans Benefits Administration | Minneapolis VA Medical Center - Cardiology Department
Minneapolis, Minnesota, 55417, United States
Mayo Clinic - Rochester
Rochester, Minnesota, 55905, United States
Minneapolis Heart Institute
Saint Paul, Minnesota, 55102, United States
Jackson Heart Clinic | Jackson, MS
Jackson, Mississippi, 39216, United States
Cardiology Associates Research, LLC
Tupelo, Mississippi, 38801, United States
St. Louis Heart & Vascular, PC
St Louis, Missouri, 63136, United States
CHI Health Clinic Heart Institute - Grand Island
Grand Island, Nebraska, 68803, United States
Advanced Heart Care, LLC | Bridgewater, NJ
Bridgewater, New Jersey, 08807, United States
NJ Heart | Linden, NJ
Linden, New Jersey, 07036, United States
Garden State Heart Care
Manalapan, New Jersey, 07726, United States
Inspira Medical Centers | Clinical Research Office
Mullica Hill, New Jersey, 08062, United States
The Valley Hospital, Inc.
Ridgewood, New Jersey, 07450, United States
Cooper Specialty Care at Voorhees
Voorhees Township, New Jersey, 08043, United States
IMA Clinical Research | Warren, NJ
Warren Township, New Jersey, 07059, United States
Circuit Clinical/Crystal Run
Middletown, New York, 10941, United States
NYU Langone Health | NYU Langone Medical Associates Chelsea - Cardiovascular Research
New York, New York, 10001, United States
Division of Cardiovascular Research at Peconic Bay Med Ctr
Riverhead, New York, 11901, United States
Great Lakes Medical Research | Westfield, NY
Westfield, New York, 14787, United States
University of North Carolina at Chapel Hill | Cardiology Department
Chapel Hill, North Carolina, 27514, United States
Duke University | Duke Clinical Research Institute - Participant Research Operations
Durham, North Carolina, 27710-4000, United States
Duke Univ. Medical Center
Durham, North Carolina, 27710, United States
Medication Management | Greensboro - Cardiology
Greensboro, North Carolina, 27408, United States
Clinical Trials of America, Inc.
Mount Airy, North Carolina, 27030, United States
Lillestol Research LLC | Fargo, ND
Fargo, North Dakota, 58104, United States
Aultman | Aultman Hospital Main Campus - Clinical Trials
Canton, Ohio, 44710, United States
Kettering Health Network | Research Institute
Kettering, Ohio, 45429, United States
Rama Research LLC | Marion, OH
Marion, Ohio, 43302-6774, United States
ProMedica Toledo Hospital
Toledo, Ohio, 43615, United States
South Oklahoma Heart Research, LLC
Oklahoma City, Oklahoma, 73135, United States
Oregon Health and Science University
Portland, Oregon, 97239, United States
Capital Area Research | Camp Hill, PA
Camp Hill, Pennsylvania, 17011, United States
Doylestown Hospital
Doylestown, Pennsylvania, 18901, United States
University of Pittsburgh Medical Center, Hamot | Clinical Trials and Research
Erie, Pennsylvania, 16507, United States
Pennsylvania State University College of Medicine
Hershey, Pennsylvania, 17033, United States
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
Einstein Healthcare Network
Philadelphia, Pennsylvania, 19141, United States
University of Pittsburgh Medical Center Health System
Pittsburgh, Pennsylvania, 15219, United States
Geisinger Community Medical Center
Scranton, Pennsylvania, 18510, United States
Geisinger Wyoming Valley Medical Center
Wilkes-Barre, Pennsylvania, 18711, United States
Main Line Health
Wynnewood, Pennsylvania, 19096, United States
Cardiology Consultants of Philadelphia | Yardley
Yardley, Pennsylvania, 19067, United States
Lifespan | The Miriam Hospital - Cardiovascular Research
Providence, Rhode Island, 02906, United States
AnMed Clinical Research
Anderson, South Carolina, 29621, United States
Medical University of South Carolina - Cardiology
Charleston, South Carolina, 29425, United States
Piedmont Research Partners LLC
Fort Mill, South Carolina, 29707, United States
Accellacare | Mt. Pleasant, SC
Ladson, South Carolina, 29456, United States
Carolina Heart Specialists | Lancaster, SC
Lancaster, South Carolina, 29720, United States
Rapid City Regional Hospital
Rapid City, South Dakota, 57701, United States
Sanford USD Medical Center
Sioux Falls, South Dakota, 57117, United States
Holston Medical Group - Bristol
Bristol, Tennessee, 37620, United States
Erlanger Health, Inc.
Chattanooga, Tennessee, 37403, United States
Stern Cardiovascular Center
Germantown, Tennessee, 38138, United States
Apex Research Foundation, LLC. | Jackson, TN
Jackson, Tennessee, 38301, United States
Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Cardiovascular Research of Knoxville
Powell, Tennessee, 37849, United States
PharmaTex Research, LLC
Amarillo, Texas, 79109, United States
Southwest Family Medicine Associates | Dallas, TX
Dallas, Texas, 75235, United States
Prime Revival Reserach Institute, LLC | Denton, TX
Denton, Texas, 76201, United States
David Turbay MD PLLC
El Paso, Texas, 79905, United States
Texas Health Research & Education Institute
Fort Worth, Texas, 76104, United States
Texas Health Physicians Group - Fort Worth
Fort Worth, Texas, 76107, United States
University of Texas Medical Branch at Galveston
Galveston, Texas, 77555-0587, United States
Houston Methodist Hospital
Houston, Texas, 77030, United States
TCR Institute
Kingwood, Texas, 77339, United States
North Dallas Research Associate | McKinney, TX
McKinney, Texas, 75069-1780, United States
North Texas Research Associates
McKinney, Texas, 75071, United States
Styde Research LLC | Plano, TX
Plano, Texas, 75093, United States
South Texas Cardiovascular Consultants, PLLC
San Antonio, Texas, 78201, United States
Clinical Advancement Center, PLLC
San Antonio, Texas, 78212-4740, United States
Mt. Olympus Medical Research
Sugar Land, Texas, 77479, United States
Northwest Houston Clinical Research, PLLC - Houston Heart Center | Tomball, TX
Tomball, Texas, 77375, United States
Tyler Cardiovascular Consultants | Tyler, TX
Tyler, Texas, 75701, United States
CHRISTUS Trinity | Mother Frances Louis and Peaches Owen Heart Hospital - Electrophysiology Clinic
Tyler, Texas, 75702, United States
Intermountain Healthcare | Cardiovascular Research Department
Murray, Utah, 84107, United States
Inova Fairfax Hospital - Fairfax
Fairfax, Virginia, 22031, United States
Virginia Heart
Falls Church, Virginia, 22042, United States
Carient Heart and Vascular
Manassas, Virginia, 20109, United States
York Clinical Research, LLC | Norfolk, VA
Norfolk, Virginia, 23504, United States
Hunter Holmes McGuire Veterans Affairs Medical Center
Richmond, Virginia, 23249-0001, United States
Virginia Commonwealth University
Richmond, Virginia, 23284, United States
Sound Medical Research | Sound Medical Research of Port Orchard
Port Orchard, Washington, 98366, United States
Confluence Health
Wenatchee, Washington, 98801, United States
Instituto de Investigaciones Clinicas Bahia Blanca | Bahia Blanca, Argentina
Bahía Blanca, Buenos Aires, 8000, Argentina
Centro de Investigación y Prevención Cardiovascular
General Arenales, Buenos Aires, C1061AAS, Argentina
Hospital Italiano de La Plata | Clinical Research Department
La Plata, Buenos Aires, B1900, Argentina
Centro de Investigaciones Medicas Lanus | Buenos Aires, Argentina
Lanús, Buenos Aires, B1824, Argentina
Instituto de Investigaciones Clinicas de Mar del Plata | Mar del Plata, Argentina
Mar del Plata, Buenos Aires, B7600FZ0, Argentina
CardioAlem Investigaciones | San Isidro, Argentina
San Isidro, Buenos Aires, B1642DCD, Argentina
Instituto de Investigaciones Clínicas (IIC) San Nicolas | San Nicolas de los Arroyos, Argentina
San Nicolás de los Arroyos, Buenos Aires, B2900DMH, Argentina
Centro de Investigaciones Medicas Temperley | Buenos Aires, Argentina
Temperley, Buenos Aires, B1834GUK, Argentina
Instituto De Investigaciones Clinicas Zarate | Zarate, Argentina
Zárate, Buenos Aires, B2800DGH, Argentina
Centro de Investigaciones Metabolicas | Ciudad de Autonoma de Buenos Aires, Argentina
Buenos Aires, Ciudad Auton. de Buenos Aires, C1056ABJ, Argentina
CEDIC Centro de Investigación Clínica | Buenos Aires, Argentina
CABA, Ciudad Auton. de Buenos Aires, C1018DES, Argentina
Centro de Especialidades Medicas (Cemedic) | Cardiology Department
Villa Luro, Ciudad Auton. de Buenos Aires, C1440CFD, Argentina
Consultorios Integrados Rosario | Instituto Medico de la Fundacion de Estudios Clinicos
Rosario, Santa Fe Province, S2000DEJ, Argentina
Laboratorio de Hemostasia y Trombosis | Rosario, AR
Rosario, Santa Fe Province, S2000DTB, Argentina
Investigaciones Clinicas Tucuman | San Miguel de Tucuman, Argentina
San Miguel de Tucumán, Tucumán Province, T4000ICL, Argentina
Instituto de Cardiologia de Corrientes Juana F. Cabral | Corrientes, Argentina
Corrientes, 3400, Argentina
Centro de Investigaciones Clinicas del Litoral | Santa Fe, Argentina
Santa Fe, S3000FWO, Argentina
The Canberra Hospital
Garran, Australian Capital Territory, 2605, Australia
Blacktown Hospital
Blacktownn, New South Wales, 2148, Australia
Concord Repatriation General Hospital
Concord, New South Wales, 2139, Australia
South Western Sydney Local Health District | Liverpool Hospital - Stroke and Neurovascular Department
Liverpool, New South Wales, 2170, Australia
John Hunter Hospital
New Lambton, New South Wales, 2305, Australia
Illawarra Shoalhaven Local Health District
Wollongong, New South Wales, 2500, Australia
Advara HealthCare Wesley
Auchenflower, Queensland, 4066, Australia
Sunshine Coast University Hospital
Birtinya, Queensland, 4575, Australia
Royal Brisbane & Women's Hospital
Brisbane, Queensland, 4029, Australia
The Prince Charles Hospital
Herston, Queensland, 4029, Australia
Redcliffe District Hospital
Redcliffe, Queensland, 4020, Australia
Gold Coast University Hospital
Southport, Queensland, 4215, Australia
Core Research Group Pty Ltd. | Brisbane, Australia
Taringa QLD, Queensland, 4068, Australia
Nightingale Research
Adelaide, South Australia, 5000, Australia
Royal Adelaide Hospital
Adelaide, South Australia, 5000, Australia
Flinders Medical Centre
Bedford Park, South Australia, 5042, Australia
Advara HealthCare Leabrook
Leabrook, South Australia, 5068, Australia
Queen Elizabeth Hospital AUS
Woodville South, South Australia, 5011, Australia
Grampians Health Ballarat
Ballarat, Victoria, 3350, Australia
Eastern Health
Box Hill, Victoria, 3128, Australia
Barwon Health
Geelong, Victoria, 3220, Australia
Baker Heart and Diabetes Institute
Hoppers Crossing, Victoria, 3029, Australia
Cabrini Malvern
Malvern, Victoria, 3144, Australia
The Alfred Hospital
Melbourne, Victoria, 3004, Australia
Royal Melbourne Hospital
Parkville, Victoria, 3050, Australia
Advara HeartCare Melbourne
Ringwood, Victoria, 3135, Australia
The Avenue Cardiovascular Centre
St Kilda East, Victoria, 3183, Australia
Fiona Stanley Hospital
Murdoch, Western Australia, 6961, Australia
Advara HealthCare Joondalup
Perth, Western Australia, 6150, Australia
Nepean Hospital
Kingswood, 2747, Australia
Klinikum Klagenfurt | Innere Medizin und Kardiologie
Klagenfurt, Carinthia, 9020, Austria
Landesklinikum Mistelbach|Kardiologie u. Internistische Med
Mistelbach, Lower Austria, 2130, Austria
UK St. Poelten | Innere Med III
Sankt Pölten, Lower Austria, 3100, Austria
MedUni Graz | Kardiologie
Graz, Styria, 8036, Austria
Landeskrankenhaus Hall | Abteilung fuer Innere Medizin
Hall in Tirol, Tyrol, 6060, Austria
MedUni Innsbruck | Kardiologie und Angiologie
Innsbruck, Tyrol, 6020, Austria
Krankenhaus St. Josef Braunau | Innere Medizin I
Braunau am Inn, Upper Austria, 5280, Austria
Elisabethinen Linz | Kardiologie, Angiologie & Intensiv Med
Linz, Upper Austria, 4020, Austria
Kepler UK Linz | Kardiologie & Intensivmedizin Campus III
Linz, Upper Austria, 4021, Austria
Klinikum Wels-Grieskirchen | Innere Medizin II
Wels, Upper Austria, 4600, Austria
MedUni Wien | Innere Medizin II, Kardiologie
Vienna, Vienna, 1090, Austria
Klinik Floridsdorf | Herz-, Gefaess- u. Kardio Ambulaz
Vienna, Vienna, 1210, Austria
LKH Feldkirch | Innere Medizin I mit Kardiologie
Feldkirch, Vorarlberg, 6800, Austria
Uniklinikum Salzburg|Innere Medizin II, Kardiologie
Salzburg, 5020, Austria
Hanusch Krankenhaus | 2. Medizinische Abteilung
Vienna, 1140, Austria
Imed19-privat
Vienna, 1190, Austria
Imelda Vzw | Study Cardiology
Bonheiden, Antwerpen, 2820, Belgium
Antwerp University Hospital | Cardiology Department
Edegem, Antwerpen, 2650, Belgium
GZA Ziekenhuizen | Saint Augustine Campus - Cardiology Department
Wilrijk, Antwerpen, 2610, Belgium
CHC MontLégia Neurology Department
Liège, Liège, 4000, Belgium
University Hospital Louvain Namur | Godinne - Cardiology Department
Yvoir, Namur, 5530, Belgium
AZ St-Lucas Campus St-Lucas - Cardiology
Ghent, Oost-Vlaanderen, 9000, Belgium
Maria Middelares General Hospital | Cardiology Department
Ghent, Oost-Vlaanderen, 9000, Belgium
UZ Leuven Gasthuisberg
Leuven, Vlaams Brabant, 3000, Belgium
Groeninge Algemeen Ziekenhuis | Campus Kennedylaan - Cardiology Departement
Kortrijk, West-Vlaanderen, 8500, Belgium
Algemeen Stedelijk Ziekenhuis Campus Aalst
Aalst, 9300, Belgium
OL Vrouwziekenhuis - Campus Aalst
Aalst, 9300, Belgium
ZNA Middelheim
Antwerp, 2020, Belgium
Algemeen Ziekenhuis Klina | Cardiology Department
Brasschaat, 2930, Belgium
AZ Sint-Jan Brugge-Oostende | Sint-Jan - Cardiology
Bruges, 8000, Belgium
CU Saint-Luc/UZ St-Luc
Bruxelles - Brussel, 1200, Belgium
AZ Sint Blasius, Cardiology, Dendermonde
Dendermonde, 9200, Belgium
AZ Sint-Maarten
Duffel, 2570, Belgium
Ziekenhuis Oost-Limburg | Genk, Sint-Jan campus - Cardiology Department
Genk, 3600, Belgium
Grand Hôpital de Charleroi
Gilly, 6060, Belgium
Jessa Ziekenhuis
Hasselt, 3500, Belgium
Citadelle Hospital | Cardiology Department
Liège, 4000, Belgium
AZ Delta | Clinical Trial Center - Cardiology
Roeselare, 8800, Belgium
Vitaz | Sint-Niklaas Hospital - Cardiology Department
Sint-Niklaas, 9100, Belgium
Hospital Cardio Pulmonar | Salvador, Brazil
Salvador, Estado de Bahia, 40170-130, Brazil
Hospital das Clinicas da Universidade Federal de Goias | Centro de Pesquisa em Cardiologia
Goiânia, Goiás, 74605-020, Brazil
Cardresearch Cardiologia Assistencial e de Pesquisa | Belo Horizonte, Brazil
Belo Horizonte, Minas Gerais, 30150-240, Brazil
Hospital Maternidade e Pronto Socorro Santa Lucia | Hospital do Coracao - Research Center
Poços de Caldas, Minas Gerais, 37706-106, Brazil
Quanta Diagnostico Por Imagem | Research and Innovation Department
Curitiba, Paraná, 80045-170, Brazil
Nucleo de Pesquisa Clinica | Curitiba, Brazil
Curitiba, Paraná, 80730-150, Brazil
Centro Medico Sao Francisco | Curitiba, Brazil
Curitiba, Paraná, 80810-050, Brazil
Sociedade Hospitalar Angelina Caron | Departamento de Ensino e Pesquisa
Paraná, Paraná, 83430-000, Brazil
Irmandade da Santa Casa de Misericordia de Porto Alegre | Hospital Sao Francisco - Centro Medico Pesquisa Clinica Cardiologia
Porto Alegre, Rio Grande do Sul, 90020-090, Brazil
Hospital de Clinicas de Porto Alegre | Clinical Research Center - Surgery Research Center
Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
FZ Pesquisa e Servicos em Cardiologia | Porto Alegre, Brazil
Porto Alegre, Rio Grande do Sul, 91350-200, Brazil
CardioBlu | Unidade Sabin
Blumenau, Santa Catarina, 89010-500, Brazil
Centro de Pesquisa Clinica do Coração | Aracaju, Brasil
Aracaju, Sergipe, 49055-530, Brazil
UNESP Faculdade de Medicina de Botucatu | UPECLIN
Botucatu, São Paulo, 18618-970, Brazil
Campinas Clinical Research Institute (IPECC) | Campinas, Brazil
Campinas, São Paulo, 13060-080, Brazil
Instituto do Coração de Marilia | Marilia, Brasil
Marília, São Paulo, 17515-000, Brazil
Hospital e Maternidade Christovao da Gama | Santo Andre Medical Centre - Cardiology Department
Santo André, São Paulo, 09030-010, Brazil
Hospital de Base | Integrated Research Center
São José do Rio Preto, São Paulo, 15090-000, Brazil
Irmandade da Santa Casa de Misericordia de Sao Paulo | Hospital Central - Cardiology Department
São Paulo, São Paulo, 01221-020, Brazil
Hospital Samaritano Paulista | Clinical Research Department
São Paulo, São Paulo, 01317-002, Brazil
Instituto Dante Pazzanese de Cardiologia | Divisao de Pesquisa
São Paulo, São Paulo, 04012-909, Brazil
Hospital e Maternidade Sao Luiz
São Paulo, São Paulo, 04321-150, Brazil
Hospital PUC-Campinas | Centro de Pesquisa Clínica Sao Lucas
São Paulo, São Paulo, 13034-685, Brazil
Eurolatino Pesquisas Medicas | Uberlandia, MG
Minas Gerais, 38400-368, Brazil
Hospital Sao Lucas Copacabana | Clinical Research Department
Rio de Janeiro, 22.0080-040, Brazil
Hospital Alemao Oswaldo Cruz | Centro Internacional de Pesquisa
São Paulo, 01321-001, Brazil
Multiprofile Hospital for Active Treatment Puls | Clinical Trial Center
Blagoevgrad, 2700, Bulgaria
Multidisciplinary Hospital for Active Treatment Heart and Brain Burgas | Cardiology Department
Burgas, 8000, Bulgaria
Medical Center Avitsena Kardzhali | Cardiology Clinic
Kardzhali, 6600, Bulgaria
SHATC Sveti Georgi - Pernik | Pernik, Bulgaria
Pernik, 2300, Bulgaria
Medical centre Hipokrat - N EOOD
Plovdiv, 4000, Bulgaria
Multiprofile Hospital for Active Treatment Medline | Cardiology Department
Plovdiv, 4000, Bulgaria
Multiprofile Hospital for Active Treatment Sveta Karidad | Cardiology Department
Plovdiv, 4004, Bulgaria
Medical Center Rusemed EOOD | Ruse, Bulgaria
Rousse, 7000, Bulgaria
Multiprofile Hospital for Active Treatment | Shumen - First Department of Internal Medicine
Shumen, 9700, Bulgaria
General Hospital Silistra | Department of Cardiology, Structure for Interventional Cardiology
Silistra, 7500, Bulgaria
Cardiohelp Medical Centre | Sofia, Bulgaria
Sofia, 1142, Bulgaria
Diagnostic Consultative Center Ascendent | Sofia, Bulgaria
Sofia, 1202, Bulgaria
Second Medical Center Sofia EOOD
Sofia, 1202, Bulgaria
Multiprofile Hospital for Active Treatment Knyaginya Klementina Sofia EAD | Cardiology Department
Sofia, 1233, Bulgaria
Multiprofile Hospital for Active Treatment National Cardiology Hospital | Cardiology Department
Sofia, 1309, Bulgaria
University Hospital for Active Treatment Tsaritsa Joanna - ISUL | Cardiology Clinic
Sofia, 1527, Bulgaria
The University General Hospital for Active Care and Emergency Medicine Pirogov | Cardiology Department
Sofia, 1606, Bulgaria
Diagnostic-Consultative Center XX | Cardiology Department
Sofia, 1618, Bulgaria
Multiprofile Hospital for Active Treatment Sveta Sofia | Internal Diseases Department
Sofia, 1618, Bulgaria
Multiprofile Hospital for Active Treatment Trakiya Park | Cardiology Department
Stara Zagora, 6000, Bulgaria
Medical Center Zara-Med EOOD | Cardiology Department
Stara Zagora, 6010, Bulgaria
NOVA Clinic Medical Center | Varna, BG
Varna, 9020, Bulgaria
Multiprofile Hospital for Active Treatment Dr. Stefan Cherkezov | Cardiology Department
Veliko Tarnovo, 5000, Bulgaria
Edmonton Cardiology Consultants
Edmonton, Alberta, T5H 4B9, Canada
University of Alberta Hospital
Edmonton, Alberta, T6G 2B7, Canada
Interior Health - Royal Inland Hospital
Kamloops, British Columbia, V2C 2T1, Canada
Fraser Clinical Trials, Inc.
New Westminster, British Columbia, V3L 3W4, Canada
Vancouver General Hospital
Vancouver, British Columbia, V5Z 1M9, Canada
Victoria Heart Institute Foundation
Victoria, British Columbia, V8R 1B2, Canada
G.A. Research Associates, Ltd.
Moncton, New Brunswick, E1G 1A7, Canada
Memorial University of Newfoundland
St. John's, Newfoundland and Labrador, A1B3V6, Canada
QEII Health Sciences Centre
Halifax, Nova Scotia, B3H 3A7, Canada
Cambridge Cardiac Care Center
Cambridge, Ontario, N1R 6V6, Canada
Hamilton Health Sciences
Hamilton, Ontario, L8L 2X2, Canada
McMaster University Medical Centre
Hamilton, Ontario, L8L 2X2, Canada
Hamilton Med.Research Group - DCT
Hamilton, Ontario, L8M 1K7, Canada
Hamilton Medical Research Group
Hamilton, Ontario, L8M 1K7, Canada
St. Joseph's Healthcare - Hamilton
Hamilton, Ontario, L8N 4A6, Canada
Milestone Research
London, Ontario, N5W 6A2, Canada
London Health Sciences Centre | University Hospital - London Heart Rhythm Program - Cardiology
London, Ontario, N6A5A5, Canada
Oakville Cardiovascular Research
Oakville, Ontario, L6K 3W7, Canada
Dr. James Cha
Oshawa, Ontario, L1J2K1, Canada
Kawartha Cardiology Clinical Trials
Peterborough, Ontario, K9J 0B2, Canada
Heart Health Institute
Scarborough Village, Ontario, M1B 4Z8, Canada
Niagara Health - St. Catharines Site
St. Catharines, Ontario, L2S 0A9, Canada
Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5, Canada
St. Michael's Hospital
Toronto, Ontario, M5B 1W8, Canada
Toronto General Hospital UHN
Toronto, Ontario, M5G 2C4, Canada
Women's College Hospital | WCH Main Site - Women's College Research Institute - Cardiology Department
Toronto, Ontario, M5S 1B2, Canada
Dr. Louis Yao
York, Ontario, M9N 1W4, Canada
Viacar Recherches Cliniques Inc.
Brossard, Quebec, J4Z 2K9, Canada
CIUSSS Saguenay Lac-St-Jean
Chicoutimi, Quebec, G7H 5H6, Canada
Centre intégré de santé et de services sociaux de Laval, Hôp
Laval, Quebec, H7M 3L9, Canada
Centricity Research Mirabel Multispecialty
Mirabel, Quebec, J7J 2K8, Canada
Montreal Heart Institute
Montreal, Quebec, H1T 1C8, Canada
CHUM - Centre hospitalier de l'Université de Montréal
Montreal, Quebec, H2X 0C1, Canada
McGill University Health Centre - Glen Site
Montreal, Quebec, H3G1A4, Canada
CIUSSS NÎM Hôpital Sacré-Coeur
Montreal, Quebec, H4J 1C5, Canada
CHU de Québec-Université Laval
Québec, Quebec, G1R 2J6, Canada
CIUSSS de l'Estrie-CHUS, Hopital Fleurimont
Sherbrooke, Quebec, J1H 5N4, Canada
CISSSL - Hopital Pierre-Le Gardeur
Terrebonne, Quebec, J6V 2H2, Canada
Diex Research Trois-Rivières Inc.
Trois-Rivières, Quebec, G9A 4P3, Canada
Institut universitaire de cardiologie et de pneumologie de Q
Québec, G1V 4G5, Canada
The 1st Affiliated Hospital Fujian Medical University
Fuzhou, Fujian, TBC, China
Xiamen Cardiovascular Hospital Xiamen University
Xiamen, Fujian, 361006, China
Lanzhou University Second Hospital
Lanzhou, Gansu, 730030, China
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, 510000, China
Guangzhou First People Hospital
Guangzhou, Guangdong, 510180, China
The First Affiliated Hospital of Guangzhou University of TCM
Guangzhou, Guangdong, 510405, China
The First Affiliated Hospital of Jinan University
Guangzhou, Guangdong, 510630, China
Guangzhou Panyu Central Hospital
Guangzhou, Guangdong, 511400, China
The 2nd Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, TBC, China
Huizhou Central People's Hospital
Huizhou, Guangdong, 516001, China
Liuzhou Worker's Hospital
Liuchow, Guangxi, 545005, China
Hainan Provincial People's Hospital
Haikou, Hainan, 570311, China
Hainan Third People's Hospital (Province Nongken Sanya Hopt)
Sanya, Hainan, 572000, China
Cangzhou Central Hospital
Cangzhou, Hebei, 61000, China
The First Hospital of Hebei Medical Univesity
Shijiazhuang, Hebei, 50000, China
The First affiliated Hospital of Hebei North University
Zhangjiakou, Hebei, 075000, China
Daqing Oilfield General Hospital
Daqing, Heilongjiang, 163311, China
The 4th Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, 150001, China
The First Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, 150001, China
1st Affiliated Hospital of Henan Science and Technology Univ
Luoyang, Henan, 471000, China
Luoyang Third People's Hospital
Luoyang, Henan, 471002, China
Xinxiang Central Hospital
Xinxiang, Henan, 453000, China
The Central Hospital of Wuhan, Tongji Medl Collg Huazhong...
Wuhan, Hubei, 430014, China
Union Hospt Tongji Medical Colleg. Huazhong univ. Scien&Tech
Wuhan, Hubei, 430030, China
Puai Hospital,Tongji Medical College, Huazhong Univ Sci&Tech
Wuhan, Hubei, 430034, China
Renmin Hosp., Wuhan Univ.
Wuhan, Hubei, 430040, China
The Third Xiangya Hospital of Central South University
Changsha, Hunan, 410000, China
The Third Hospital of Changsha
Changsha, Hunan, 410011, China
The First Affiliated Hospital of Baotou Medical College
Baotou, Inner Mongolia, 14010, China
Baotou Central Hospital
Baotou, Inner Mongolia, 14040, China
Inner Mongolia People's Hospital
Hohhot, Inner Mongolia, 010017, China
Huai'an First People's Hospital, Nanjing Medical University
Huai'an, Jiangsu, 223300, China
Affiliated Hospital of Jiangsu University
JiangSu, Jiangsu, 212001, China
The Second Affiliated Hospital of Nanjing Medical university
Nanjing, Jiangsu, 210000, China
Nanjing First Hospital
Nanjing, Jiangsu, 210006, China
Zhongda Hospital Southeast University
Nanjing, Jiangsu, 210009, China
Nanjing Jiangning Hospital
Nanjing, Jiangsu, 211103, China
Taizhou People's Hospital
Taizhou, Jiangsu, MISSING, China
Northern Jiangsu People's Hospital
Yangzhou, Jiangsu, 225001, China
Affiliated Hospital of Yangzhou University (Yangzhou First People's Hospital)
Yangzhou, Jiangsu, 225012, China
Jiangxi Provincial People's Hospital
Nanchang, Jiangxi, 330006, China
The First Affiliated Hospital of NanChang University
Nanchang, Jiangxi, 330006, China
The Third Hospital of Nanchang
Nanchang, Jiangxi, 330009, China
Jiangxi PingXiang people's Hospital
Pingxiang, Jiangxi, 337055, China
China-Japan Union Hospital of Jilin University
Changchun, Jilin, 130031, China
Tonghua Central Hospital
Tonghua, Jilin, 134001, China
The First Affiliated Hospital of Jinzhou Medical University
Jinzhou, Liaoning, 121001, China
Panjin Liaohe Oilfield Gem Flower Hospital
Panjin, Liaoning, 124010, China
Yinchuan No.1 People's Hospital
Yinchuan, Ningxia, 750001, China
General Hospital of Ningxia Medical University
Yinchuan, Ningxia, 750004, China
Qinghai University Affiliated Hospital
Xining, Qinghai, 810001, China
Yan'an University Xianyang Hospital
Xianyang, Shaanxi, 716000, China
Jinan Central Hospital
Jinan, Shandong, 250013, China
The 2nd Affiliated Hospital of Shandong University
Jinan, Shandong, 250033, China
Qilu Hosp., Shandong Univ.
Jinan, Shandong, TBC, China
Affiliated Hospital of Jining Medical University
Jining, Shandong, 272007, China
Jining No.1 People's Hospital
Jining, Shandong, 272011, China
Taian City Central Hospital
Taian, Shandong, 271099, China
Zibo Central Hospital
Zibo, Shandong, 250036, China
Shanxi Candiovascular Hospital
Taiyuan, Shanxi, 30024, China
Shanxi Bethune Hospital
Taiyuan, Shanxi, 30032, China
Shaanxi Provincial People's Hospital
Xi’an, Shanxi, 710068, China
Yuncheng Central Hospital
Yuncheng, Shanxi, 44099, China
Chengdu Second People's Hospital
Chengdu, Sichuan, 610021, China
West China Hospital,Sichuan University
Chengdu, Sichuan, 610041, China
SichuanAcademyofMedicalSciences&SichuanProvincialPeople'sHos
Chengdu, Sichuan, 610072, China
People's Hospital of Deyang City
Deyang, Sichuan, 618000, China
The First Affiliated Hospital of Xinjiang Medical University
Ürümqi, Xinjiang, MISSING, China
The 1st Affiliated Hospital of Zhejiang University
Hangzhou, Zhejiang, 310000, China
Affiliated Hangzhou First People's Hospital, Zhejiang Univ
Hangzhou, Zhejiang, 310006, China
Ningbo First Hospital
Ningbo, Zhejiang, 315010, China
Hwa Mei Hospital, University of Chinese Academy Sciences
Ningbo, Zhejiang, 31510, China
Taizhou Hospital of Zhejiang Province
Taizhou, Zhejiang, 317099, China
The First Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, 325000, China
Beijing Chaoyang Hospital, Capital Medical University
Beijing, 100020, China
Beijing Anzhen Hospital, Capital Medical University
Beijing, 100029, China
China-Japan Friendship Hospital
Beijing, 100029, China
Peking University First Hospital
Beijing, 100034, China
Xuanwu Hospital Capital Medical University
Beijing, 100053, China
Beijing Tongren Hospital, Capital Medical University (West)
Beijing, 100730, China
Peking Union Medical College Hospital CAMS
Beijing, 100730, China
Beijing Tsinghua Changgung Hospital
Beijing, MISSING, China
Zhongshan Hospital, Fudan University
Shanghai, 200032, China
Huashan Hospital, Fudan University
Shanghai, 200040, China
Shanghai General Hospital
Shanghai, 200080, China
Shanghai Putuo District Central Hospital
Shanghai, 200333, China
Tianjin People's Hospital
Tianjin, 300000, China
Teda International Cardiovascular Hospital
Tianjin, 300457, China
Benedor s.r.o.
Ostrava - Poruba, Moravskoslezský kraj, 708 68, Czechia
Cevni Kulatak
Prague, Prague, 160 00, Czechia
Cardio Research s.r.o.
Zlín, Zlín, 760 01, Czechia
Kardiologicka ambulance Brno s.r.o.
Brno, 612 00, Czechia
Fakultni nemocnice Brno
Brno, 625 00, Czechia
Vojenska nemocnice Brno
Brno, 63600, Czechia
Amkardia s.r.o.
Brno, 639 00, Czechia
Kardiologicka ambulance Cormedico
Bruntál, 792 01, Czechia
Nemocnice Ceske Budejovice, a.s. Department of kardiologie
České Budějovice, 370 01, Czechia
Mrozek kardiologie
Frýdek-Místek, 73801, Czechia
MATMED s.r.o.
Hodonín, 69501, Czechia
Krajska Nemocnice Liberec
Liberec, 460 63, Czechia
Fakultni Nemocnice Olomouc
Olomouc, 77900, Czechia
Fakultni nemocnice Plzen
Pilsen, 301 00, Czechia
Fakultni nemocnice Kralovske Vinohrady
Prague, 10034, Czechia
Institut Klinicke a Experimentalni Mediciny
Prague, 140 21, Czechia
Fakultni nemocnice v Motole
Prague, 150 06, Czechia
Medicon Poliklinika Holesovice
Prague, 170 00, Czechia
Nemocnice Slany
Slaný, 274 01, Czechia
MUDr. Michalik s.r.o.
Zábřeh nad Odrou, 700 30, Czechia
Region Nordjylland | Aalborg University Hospital - Cardiology Department
Aalborg, 9000, Denmark
Region Midtjylland | Aarhus University Hospital - Heart Diseases - Clinical Research
Århus N, 8200, Denmark
Capital Region | Amager Hospital - Cardiology Outpatient Clinic
Copenhagen, 2300, Denmark
Sydvestjysk Sygehus Esbjerg | Kardiologisk Forskningsenhed
Esbjerg, 6700, Denmark
Capital Region | Frederiksberg Hospital - Department of Cardiology Research
Frederiksberg, 2000, Denmark
Capital Region | Gentofte Hospital - Cardiology Research
Hellerup, 2900, Denmark
Capital Region | Herlev Hospital - Department of Heart Disease
Herlev, 2730, Denmark
Region Midtjylland | Regionshospitalet Godstrup - Clinic for Heart Research
Herning, 7400, Denmark
Capital Region | Nordsjaellands Hospital - Hillerod - Cardiology Department
Hilleroed, 3400, Denmark
Region Nordjylland | Hjoerring - Cardiology Department
Hjørring, DK-9800, Denmark
Region Sjælland | Holbaek Sygehus - Cardiology department
Holbæk, 4300, Denmark
Capital Region | Hvidovre Hospital - Department of Cardiology
Hvidovre, 2650, Denmark
Sygehus Lillebaelt | Kolding Sygehus - Medicinske Sygdomme
Kolding, 6000, Denmark
Sjællands Universitetshospital Roskilde - Hormon og stofskiftesygdomme
Roskilde, 4000, Denmark
Odense University Hospital | Svendborg Hospital - Cardiovascular Research Unit
Svendborg, 5700, Denmark
Region Midtjylland | Viborg Regional Hospital - Cardiology - Heart Research
Viborg, 8800, Denmark
Rapla Family Doctors Centre
Rapla, 79515, Estonia
Dr Signe Alliksoo Family Doctors Practice
Tallinn, 10138, Estonia
East Tallinn Central Hospital
Tallinn, 10138, Estonia
Pirita Family Doctors Centre
Tallinn, 11911, Estonia
North Estonia Medical Centre Foundation
Tallinn, 13419, Estonia
Office of Arvo Rosenthal
Tallinn, 13419, Estonia
West Tallinn Central hospital
Tallinn, EE-10617, Estonia
Tartu University Hospital
Tartu, 50406, Estonia
HUS Jorvin sairaala
Espoo, 2740, Finland
StudyCor Oy
Jyväskylä, 40620, Finland
Keski-Pohjanmaan keskussairaala
Kokkola, 67200, Finland
Health Step Finland Oy
Kuopio, 70210, Finland
Kuopion yliopistollinen sairaala
Kuopio, FIN- 70029, Finland
Päijät-Hämeen keskussairaala
Lahti, 15850, Finland
Oulun yliopistollinen sairaala
Oulu, 90220, Finland
Tays Sydänsairaala
Tampere, 33520, Finland
Terveystalo Pulssi
Turku, 20100, Finland
Turun yliopistollinen keskussairaala
Turku, 20520, Finland
Centre Hospitalier Universitaire - Angers
Angers, 49933, France
Centre Hospitalier Intercommunal de la Côte Basque-Bayonne
Bayonne, 64100, France
Hopital Charles Nicolle Chu Rouen
Bois-Guillaume, 76320, France
Hôpital La Cavale Blanche - CHU de Brest
Brest, 29200, France
Hôpital Louis Pradel - Bron
Bron, 69677, France
CHU de Caen - Hôpital Côte de Nacre
Caen, 14033, France
Hôpital Trousseau - Tours
Chambray-lès-Tours, 37170, France
Centre Hospitalier - Cholet
Cholet, 49325, France
Hôpital Henri Mondor
Créteil, 94010, France
CHU GRENOBLE - Hopital Michallon
Grenoble, 38043, France
Centre Hospitalier Départemental Vendée
La Roche-sur-Yon, 85925, France
Centre Hospitalier Louis Pasteur
Le Coudray, 28630, France
Centre Hospitalier du Docteur Schnaffer - Lens
Lens, 62307, France
Hôpital Dupuytren
Limoges, 87042, France
Hôpital Arnaud de Villeneuve - Montpellier
Montpellier, 34059, France
Hôpital Guillaume et René Laennec - Nantes
Nantes, 44035, France
Nouvelles Cliniques Nantaises - Nantes
Nantes, 44277, France
Hôpital Pasteur - Nice
Nice, 6002, France
Hopital Carémeau - Nîmes
Nîmes, 30029, France
Institut Mutualiste Montsouris
Paris, 75014, France
Hôpital de la Pitié-Salpétrière
Paris, 75651, France
Hopital Européen Georges Pompidou - Paris
Paris, 75908, France
Hôpital Cardiologique - Pessac
Pessac, 33604, France
CHU Rennes, H Pontchaillou, Cardiologie
Rennes, 35033, France
Centre Hospitalier Régional - Saint Brieuc
Saint-Brieuc, 22000, France
Centre de Cardiologie Nord - Saint Denis
Saint-Denis, 93207, France
Hôpital Civil - Strasbourg
Strasbourg, 67091, France
CHI Toulon - H La Seyne - Cardiologie
Toulon, 83000, France
Hôpital de Rangueil - Toulouse
Toulouse, 31059, France
Clinique Pasteur - Toulouse
Toulouse, 31076, France
Centre Hospitalier Gustave Dron - Tourcoing
Tourcoing, 59280, France
Centre Hospitalier - Valenciennes Cedex
Valenciennes, 59322, France
Centre Hospitalier Universitaire de Nancy
Vandœuvre-lès-Nancy, 54500, France
Universitaets Herzzentrum Bad Krozingen
Bad Krozingen, Baden-Wurttemberg, 79189, Germany
Uni-Klinikum Heidelberg | Kardiologie Angiologie Pneumologie
Heidelberg, Baden-Wurttemberg, 69120, Germany
MEDICLIN Herzzentrum Lahr|Kardiologie
Lahr, Baden-Wurttemberg, 77933, Germany
Cardio Centrum Ludwigsburg
Ludwigsburg, Baden-Wurttemberg, 71634, Germany
Hegau-Bodensee-Klinikum Singen|I. Medizinische Klinik
Singen, Baden-Wurttemberg, 78224, Germany
Klinikum Fulda gAG|Medizinische Klinik I
Fulda, Hesse, 36043, Germany
Medizinische Hochschule Hannover|Kardiologie und Angiologie
Hanover, Lower Saxony, 30625, Germany
UniKlinikum Aachen|Kardio, Angio, Intensivmedizin
Aachen, North Rhine-Westphalia, 52074, Germany
St. Vinzenz-Hospital|Innere Medizin III, Kardiologie
Cologne, North Rhine-Westphalia, 50733, Germany
St.Johannes-Hospital|Klinik fuer Innere Medizin I
Dortmund, North Rhine-Westphalia, 44137, Germany
Ev. Krankenhaus Hagen-Haspe|Kardiologie und Rhythmologie
Hagen, North Rhine-Westphalia, 58135, Germany
Klinikum Lüdenscheid - Märkische Kliniken GmbH
Lüdenscheid, North Rhine-Westphalia, 58515, Germany
Kliniken Maria Hilf GmbH
Mönchengladbach, North Rhine-Westphalia, 41063, Germany
Sana-Klinikum Remscheid|Kardio, Angio, Pneumo u. Intensivmed
Remscheid, North Rhine-Westphalia, 42859, Germany
Josephs-Hospital|Kardiologie, Rhythmologie und Angiologie
Warendorf, North Rhine-Westphalia, 48231, Germany
Forschungszentrum Ruhr KliFoCenter GmbH
Witten, North Rhine-Westphalia, 58455, Germany
Universitätsmedizin der Johannes Gutenberg Universität Mainz
Mainz, Rhineland-Palatinate, 55101, Germany
Klinikum Worms gGmbH|Kardiologie und Angiologie
Worms, Rhineland-Palatinate, 67550, Germany
Siteworks Pruefzentrum Voelklingen
Völklingen, Saarland, 66333, Germany
Klinische Forschung Dresden | Dresden, Germany
Dresden, Saxony, 01069, Germany
Krankenhaus Dresden-Friedrichstadt
Dresden, Saxony, 1067, Germany
Praxisklinik Herz und Gefaesse|Kardiologische Ambulanz
Dresden, Saxony, 1099, Germany
Uniklinik Leipzig / Kardiologie
Leipzig, Saxony, 4103, Germany
Praxis Hr. Dr. med. Jens Taggeselle
Markkleeberg, Saxony, 04416, Germany
Kardiologische Praxis Hr. Dr. A. Al-Zoebi
Wermsdorf, Saxony, 4779, Germany
Uniklinik Jena / Kardiologie
Jena, Thuringia, 7747, Germany
Uniklinikum Hamburg-Eppendorf|Klinik für Kardiologie
Hamburg, 20246, Germany
Klinische Forschung Hamburg GmbH
Hamburg, 20253, Germany
Cardiologicum Hamburg
Hamburg, 22041, Germany
KAT General Hospital of Athens
Kifissia, Attica, 14561, Greece
University General Hospital of Alexandroupolis
Alexandroupoli, 68100, Greece
General Hospital of Athens "Evangelismos"
Athens, 10676, Greece
HIPPOKRATION General Hospital of Athens
Athens, 115 27, Greece
Naval Hospital of Athens
Athens, 11521, Greece
G. GENNIMATAS General State Hospital of Athens
Athens, 11527, Greece
LAIKO General Hospital of Athens
Athens, 11527, Greece
General Hospital of Athens "ALEXANDRA"
Athens, 11528, Greece
University General Hospital of Athens "ATTIKON"
Chaïdári, 12462, Greece
Thriassio General Hospital of Elefsina
Elefsina, 19018, Greece
University General Hospital of Heraklion
Heraklion, 711 10, Greece
Univ. General Hospital of Ioannina
Ioannina, 45500, Greece
University General Hospital of Ioannina
Ioannina, 45500, Greece
Univ. General Hospital of Larissa
Larissa, 41110, Greece
University General Hospital of Larissa
Larissa, 41110, Greece
MITERA Hospital
Marousi, 15123, Greece
Konstantopoulio General Hospital of Nea Ionia - AGIA OLGA
Nea Ionia, 14233, Greece
University General Hospital of Patra
Pátrai, 26504, Greece
AHEPA University General Hospital of Thessaloniki
Thessaloniki, 54636, Greece
Hippokration General Hospital of Thessaloniki
Thessaloniki, 54642, Greece
General Hospital ASKLEPIEIO VOULAS
Voula, 16673, Greece
Cardiomobile Egeszsegugyi Szolgaltato Kft.
Balatonfüred, 8230, Hungary
Budapesti Jahn Ferenc Del-pesti Korhaz es Rendelointezet
Budapest, 1024, Hungary
Semmelweis University
Budapest, 1088, Hungary
Budapesti Uzsoki Utcai Korhaz
Budapest, 1145, Hungary
Belinus Bt.
Debrecen, 4025, Hungary
Kardio Egeszseghaz - Dr Amer Sayour Egyeni Vallakozo
Győr, 9024, Hungary
Trial Pharma Kft. Gyula
Gyula, 5700, Hungary
Somogy Varmegyei Kaposi Mor Oktato Korhaz
Kaposvár, 7400, Hungary
Komaromi Selye Janos Korhaz
Komárom, 2900, Hungary
Borsod-Abauj-Zemplen Varmegyei Korhaz es Egyetemi Oktatokorhaz
Miskolc, 3526, Hungary
TaNa Med Kft.
Mosonmagyaróvár, 9200, Hungary
Nagykanizsai Kanizsai Dorottya Korhaz
Nagykanizsa, 8800, Hungary
Medifarma-98 Egeszsegugyi, Kereskedelmi es Szolgaltato Kft.
Nyíregyháza, 4400, Hungary
Borbanya Praxis Bt.
Nyíregyháza, 4405, Hungary
Dr. Laszlo Elek Korhaz es Rendelointezet, Oroshaza
Orosháza, 5900, Hungary
Dr. Nagy Laszlo Egyeni Egeszsegugyi Vallalkozo
Orosháza, 5900, Hungary
Coromed Smo Kft
Pécs, 7623, Hungary
Pecsi Tudomanyegyetem Klinikai Kozpont
Pécs, 7624, Hungary
Tolna Varmegyei Balassa Janos Korhaz
Szekszárd, 7100, Hungary
Complex Rendelo Med Zrt.
Székesfehérvár, 8000, Hungary
Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz
Szombathely, 9700, Hungary
Belvarosi Egeszseghaz Kft.
Zalaegerszeg, 8900, Hungary
Lisie Hospital
Kochi, Kerala, 682017, India
Vijan Cardiac & Critical Care Centre
Nashik, Maharashtra, 422005, India
Asian Institute of Gastroenterology (AIG Hospital)
Hyderabad, 500032, India
King Edward Memorial (KEM) Hospital - Pune
Pune, 411 011, India
HaEmek Medical Center | Internal Medicine C Department - Research Unit
Afula, 1834111, Israel
Samson Assuta Ashdod University Hospital | Cardiology Department
Ashdod, 7747629, Israel
Barzilai Ashkelon University Medical Center | Cardiology Department
Ashkelon, 7830604, Israel
Clalit Health | Soroka Medical Center - Cardiology Department
Beersheba, 8410101, Israel
Clalit Health | Soroka Medical Center - Internal Medicine Department
Beersheba, 8410101, Israel
Assuta Hospital Be'er Sheva | Heart Institute - Clinics
Beersheba, 8489507, Israel
Hillel Yaffe Medical Center | Cardiology Department
Hadera, 3810101, Israel
Rambam Health Care Campus | Cardiology Department - Cardiology Research Unit
Haifa, 3109601, Israel
Bnai Zion Medical Center | Cardiology Department
Haifa, 3339419, Israel
Carmel Medical Center | Cardiology Department - Cardiac Catheterization Unit
Haifa, 3436212, Israel
Edith Wolfson Medical Center | Internal Medicine Department
Holon, 5822012, Israel
Shaare Zedek Medical Center | The Jesselson Integrated Heart Center - Cardiology Department
Jerusalem, 9103102, Israel
Clalit Health | Meir Medical Center - Division of Cardiology - Electrophysiology and Arrhythmias Unit
Jerusalem, 9112001, Israel
Hadassah Hebrew University Hospital Ein Kerem
Jerusalem, 9112001, Israel
Poria Medical Center | Cardiovascular Department
Lower Galilee, 15208, Israel
Galilee Medical Center | Cardiology Department
Nahariya, 2210001, Israel
Rabin Medical Center | Beilinson Hospital - Internal Medicine C Department
Petah Tikva, 4941492, Israel
Rabin Medical Center | Clinical Trials Unit - Cardiology Department
Petah Tikva, 4941492, Israel
Kaplan Medical Center | Cardiology Department - Heart Institute Research
Rehovot, 7610001, Israel
Shamir Medical Center | Cardiology Department
Rishon LeZiyyon, 6093000, Israel
Ziv Medical Center | Cardiology Department
Safed, 1311001, Israel
Tel Aviv Sourasky Medical Center | Ichilov General Hospital - Cardiology Department
Tel Aviv, 6423906, Israel
Tel-Aviv Sourasky Medical Center
Tel Aviv, 6423906, Israel
ASL2 Lanciano-Vasto-Chieti
Chieti, Abruzzo, 66013, Italy
Ente Ecclesiastico Ospedale Generale Regionale Miulli
Bari, Apulia, 70021, Italy
A.O.U. Ospedali Riuniti Foggia
Foggia, Apulia, 71122, Italy
A.O Sant'Anna-San Sebastiano
Caserta, Campania, 81100, Italy
A.O.U. Policlinico Federico II Napoli
Naples, Campania, 80131, Italy
A.O.R.N. Ospedali dei Colli (Monaldi-Cotugno-CTO)
Napoli, Campania, 80131, Italy
Azienda Unita Sanitaria Locale Di Bologna_Ospedale Maggiore Pizzardi - Cardiologia
Bologna, Emilia-Romagna, 40133, Italy
A.O.U. di Ferrara
Ferrara, Emilia-Romagna, 44124, Italy
A.O.U. di Modena - Policlinico
Modena, Emilia-Romagna, 41100, Italy
A.O.U. di Parma
Parma, Emilia-Romagna, 43126, Italy
Asl Roma 2
Rome, Lazio, 157, Italy
A.O.U. Policlinico Umberto I
Rome, Lazio, 161, Italy
ASST Papa Giovanni XXIII
Bergamo, Lombardy, 24127, Italy
ASST del Garda
Brescia, Lombardy, 25085, Italy
Ospedale San Raffaele s.r.l. - Cardiologia Clinica
Milan, Lombardy, 20132, Italy
IRCCS Centro Cardiologico Monzino
Milan, Lombardy, 20138, Italy
Humanitas Mirasole S.p.A. - Centro Trombosi e Malattie Emorragiche
Rozzano, Lombardy, 20089, Italy
ASST Sette Laghi
Varese, Lombardy, 21049, Italy
A.O.U. Maggiore della Carità
Novara, Piedmont, 28100, Italy
A.O.U. Policlinico G. Martino
Messina, Sicily, 98124, Italy
A.O.U. Ospedali Riuniti "Umberto I - G.M.Lancisi - G.Salesi"
Ancona, The Marches, 60126, Italy
ASUR Marche - Area Vasta 5
Ascoli Piceno, The Marches, 63074, Italy
AUSL Toscana Sud-Est
Arezzo, Tuscany, 52044, Italy
A.O.U. Careggi
Florence, Tuscany, 50134, Italy
A.O.U. Pisana
Pisa, Tuscany, 56126, Italy
A.O. di Perugia
Perugia, Umbria, 6129, Italy
A.O.U. di Padova
Padua, Veneto, 35128, Italy
ULSS2 Marca Trevigiana
Treviso, Veneto, 31015, Italy
ULSS3 Serenissima
Venezia, Veneto, 30174, Italy
Kasugai Municipal Hospital
Kasugai, Aichi-ken, 486-8510, Japan
Japan Community Healthcare. Organization Chukyo Hospital
Nagoya, Aichi-ken, 457-8510, Japan
Japanese RedCross Aichi Medical Center Nagoya Daini Hospital
Nagoya, Aichi-ken, 466-8650, Japan
Japan Culture and Welfare Federation of Agricultural Cooperatives | Toyota Kosei Hospital
Toyota, Aichi-ken, 470-0396, Japan
Chiba Tokushukai Hospital | Clinical Trial Center
Funabashi, Chiba, 274-8503, Japan
Nippon Medical School Chiba Hokusoh Hospital | Clinical Trial Office
Inzai, Chiba, 270-1694, Japan
Kimitsu Chuo Hospital
Kisarazu, Chiba, 292-8535, Japan
Toho University Sakura Medical Center
Sakura, Chiba, 285-8741, Japan
Matsuyama Shimin Hospital
Matsuyama, Ehime, 790-0067, Japan
Munakata Suikokai General Hospital | Cardiology Department
Fukutsu, Fukuoka, 811-3298, Japan
Nakamura Cardiovascular Clinic
Itoshima, Fukuoka, 819-1104, Japan
Kokura Memorial Hospital
Kitakyushu, Fukuoka, 802-8555, Japan
Steel Memorial Yawata Hospital
Kitakyushu, Fukuoka, 805-8508, Japan
Go Neurosurgical Clinic
Nakagawa, Fukuoka, 811-1244, Japan
Onga Nakama Medical Association Onga Hospital
Onga-gun, Fukuoka, 811-4342, Japan
Fukuoka Shinmizumaki Hospital | Clinical Trial Management Office
Tateyashiki, Mizumakimachi, on, Fukuoka, 807-0051, Japan
Yanagawa Hospital
Yanagawa, Fukuoka, 832-0077, Japan
Japan Culture and Welfare Federation of Agricultural Cooperatives | ShirakawaKosei General Hospital
Shirakawa, Fukushima, 105-0021, Japan
National Hospital Organization Takasaki General Medical Center
Takasaki, Gunma, 370-0829, Japan
Mazda Motor Corporation Mazda Hospital
Aki-gun, Hiroshima, 735-8585, Japan
Asahikawa City Hospital
Asahikawa, Hokkaido, 070-8610, Japan
Hakodate National Hospital
Hakodate, Hokkaido, 041-8512, Japan
Hakodate Municipal Hospital
Hakodate, Hokkaido, 041-8680, Japan
Matsuda Cardiovascular clinic
Sapporo, Hokkaido, 003-0026, Japan
Mita Internist and Cardiology Clinic | Hokkaido, Japan
Sapporo, Hokkaido, 006-0852, Japan
Teine Keijinkai Hospital
Sapporo, Hokkaido, 006-8555, Japan
Hanaoka Seishu Memorial Hospital
Sapporo, Hokkaido, 062-0003, Japan
Miyanosawa Clinic of Internal Medicine and Cardiology
Sapporo, Hokkaido, 063-0826, Japan
Miyanomori Memorial Hospital
Sapporo, Hokkaido, 064-8570, Japan
Sapporo Higashi Tokushukai Hospital
Sapporo, Hokkaido, 065-0033, Japan
Oji General Hospital
Tomakomai, Hokkaido, 053-8506, Japan
Tomakomai City Hospital
Tomakomai, Hokkaido, 053-8567, Japan
Akashi Medical Center | Hyogo, Japan
Akashi, Hyōgo, 674-0063, Japan
Hyogo Prefectural Amagasaki General Medical Center
Amagasaki, Hyōgo, 660-8550, Japan
Hyogo Prefectural HarimaHimeji General Medical Center
Himeji, Hyōgo, 670-8560, Japan
The Veritas Hospital
Kawanishi, Hyōgo, 666-0125, Japan
Kobe City Medical Center General Hospital
Kobe, Hyōgo, 650-0047, Japan
Higashi Takarazuka Satoh Hospital
Takarazuka, Hyōgo, 665-0873, Japan
National hospital Organization Mito Medical Center
Higashiibaraki, Ibaraki, 311-3193, Japan
Ibaraki Prefectural Central Hospital
Kasama, Ibaraki, 309-1793, Japan
Mito Saiseikai General Hospital
Mito, Ibaraki, 311-4198, Japan
JA Toride Medical Center
Toride, Ibaraki, 302-0022, Japan
Tsuchiura Kyodo General Hospital
Tsuchiura, Ibaraki, 300-0028, Japan
Public Central Hospital of Matto Ishikawa | Clinical Trial Management Office
Hakusan, Ishikawa-ken, 924-8588, Japan
Kanazawa Medical University Hospital
Kahoku-gun, Ishikawa-ken, 920-0293, Japan
Ishikawa Prefectural Central Hospital
Kanazawa, Ishikawa-ken, 920-8530, Japan
National Hospital Organization Kanazawa Medical Center | Clinical Trial Management Office
Kanazawa, Ishikawa-ken, 920-8650, Japan
Komatsu Municipal Hospital
Komatsu, Ishikawa-ken, 923-8560, Japan
Iwate Prefectural Central Hospital
Morioka, Iwate, 020-0066, Japan
Kagawa Prefectural Central Hospital
Takamatsu, Kagawa-ken, 760-8557, Japan
Mitoyo General Hospital | Kagawa, Japan
Toyohama-Cho,Kanonji-City, Kagawa-ken, 769-1695, Japan
Oosumikanoya Hospital
Kanoya, Kagoshima-ken, 893-0015, Japan
Fujisawa City Hospital
Fujisawa, Kanagawa, 251-8550, Japan
Hayama Heart Center | Clinical Trial Center
Miura-gun, Kanagawa, 240-0116, Japan
Yokohama City University Medical Center
Yokohama, Kanagawa, 232-0024, Japan
Yokohama Sakae Kyosai Hospital
Yokohama, Kanagawa, 247-8581, Japan
Japan Culture and Welfare Federation of Agricultural Cooperatives | Suzuka Chuo General Hospital
Suzuka-shi, Mie-ken, 513-8630, Japan
Sendai Cardiovascular Center
Sendai, Miyagi, 981-3133, Japan
Tohoku Medical and Pharmaceutical University Hospital | Center for Clinical Research Promotion and Development
Sendai, Miyagi, 983-8512, Japan
Japan Red Cross Society Azumino Hospital
Azumino, Nagano, 399-8292, Japan
Iida Hospital
Iida, Nagano, 395-8505, Japan
North Alps Medical Center Azumi Hospital
Kitaazumi-gun, Nagano, 399-8695, Japan
Asama Nanroku Komoro Medical Center | Komoro, Japan
Komoro, Nagano, 384-8588, Japan
Japan Culture and Welfare Federation of Agricultural Cooperatives | Hokushin General Hospital
Nakano, Nagano, 383-8505, Japan
Japanese Red Cross Society Suwa Hospital
Suwa, Nagano, 392-8510, Japan
R.I.A.C Naha City Hospital
Naha, Okinawa, 902-8511, Japan
Urasoe General Hospital | Clinical Research Support Center
Urasoe, Okinawa, 901-2102, Japan
Kishiwada Tokushukai Hospital
Kishiwada, Osaka, 596-0042, Japan
Osaka Saiseikai Senri Hospital
Suita, Osaka, 565-0862, Japan
Sakurabashi Watanabe Future Medical Hospital | Department of Cardiology
Umeda Kita-Ku, Osaka-shi, Osaka, 5320001, Japan
Yao Tokushukai General Hospital | Clinical Research Center
Yao, Osaka, 581-0011, Japan
Ageo Central General Hospital
Ageo, Saitama, 362-8588, Japan
Kawaguchi Cardiovascular and Respiratory Hospital
Kawaguchi, Saitama, 333-0842, Japan
Omihachiman Community Medical Center
Ōmihachiman, Shiga, 523-0082, Japan
National Hospital Organization Hamada Medical Center
Hamada, Shimane, 697-8511, Japan
Dokkyo Medical University Hospital
Shimotsuga-gun, Tochigi, 321-0293, Japan
Tokyo Medical and Dental University Hospital
Bunkyo-ku, Tokyo, 113-8519, Japan
CliniPro Co.,Ltd. | Tokyo-Eki Center-building Clinic - Tokyo, Japan
Chuo-ku, Tokyo, 103-0027, Japan
Minamino Cardiovascular Hospital
Hachiōji, Tokyo, 192-0918, Japan
Tokyo Angel Hospital | Clinical Trial Department
Hachiōji, Tokyo, 193-0811, Japan
Nihon University Itabashi Hospital
Itabashi-ku, Tokyo, 173-8610, Japan
Machida Municipal Hospital
Machida, Tokyo, 194-0023, Japan
National Hospital Organization Tokyo Medical Center
Meguro-ku, Tokyo, 152-8902, Japan
Tokyo Saiseikai Central Hospital | Clinical Research Center
Minato-ku, Tokyo, 108-0073, Japan
Tokyo Yamate Medical Center
Shinjuku-ku, Tokyo, 169-0073, Japan
NewHeart Watanabe Institute
Suginami-ku, Tokyo, 168-0065, Japan
National Hospital Organization Disaster Medical Center
Tachikawa, Tokyo, 190-0014, Japan
JCHO Tokuyama Central Hospital
Shūnan, Yamaguchi, 745-8522, Japan
Yamanashi Prefectural Central Hospital
Kofu, Yamanashi, 400-8506, Japan
Fukui General Clinic
Fukui, 910-0067, Japan
Fukui Prefectural Hospital
Fukui, 910-8526, Japan
Social Medical Corporation the Chiyukai foundation Fukuoka Wajiro Hospital
Fukuoka, 811-0213, Japan
Fukuoka University Hospital
Fukuoka, 814-0180, Japan
Fukuoka University Nishijin Hospital
Fukuoka, 814-8522, Japan
Kyushu Central Hospital
Fukuoka, 815-8588, Japan
Gifu Heart Center
Gifu, 500-8384, Japan
Hiroshima City Hiroshima Citizens Hospital
Hiroshima, 730-8518, Japan
Tenyoukai Central Clinic
Kagoshima, 892-0822, Japan
Kagoshima Medical Center
Kagoshima, 892-0853, Japan
Chikamori Hospital
Kochi, 780-8522, Japan
Kumamoto Kinoh Hospital
Kumamoto, 860-8518, Japan
Rakuwakai Otowa Hospital
Kyoto, 607-8062, Japan
National Hospital Organization Kyoto Medical Center
Kyoto, 612-8555, Japan
Miyazaki Medical Association Hospital
Miyazaki, 880-2102, Japan
The Sakakibara Heart Institute of Okayama
Okayama, 700-0804, Japan
CMIC HealthCare Institute Co. Ltd. | Local IAA OCGMC - Okayama City Civic Hospital - Clinical Trial Centre
Okayama, 7008557, Japan
CMIC HealthCare Institute Co. Ltd. | Okayama Rosai Hospital - Clinical Trial Centre
Okayama, 7028055, Japan
Osaka Saiseikai Nakatsu Hospital
Osaka, 530-0012, Japan
Kitada Clinic
Osaka, 538-0044, Japan
Osaka Police Hospital | Clinical Research and Trial Center
Osaka, 543-0035, Japan
Nippon Life Hospital
Osaka, 550-0006, Japan
Japan Community Health Care Organization Osaka Hospital
Osaka, 553-0003, Japan
Oita Prefectural Hospital
Ōita, 870-8511, Japan
Saga Memorial Hospital
Saga, 849-0917, Japan
Sainokuni Higashiomiya Medical Center
Saitama, 331-8577, Japan
Sanai hospital
Saitama, 338-0837, Japan
Iwatsuki-minami Hospital
Saitama, 339-0033, Japan
Shizuoka City Shizuoka Hospital
Shizuoka, 420-8630, Japan
Saiseikai Wakayama Hospital | Pharmaceutical department
Wakayama, 640-8158, Japan
Doctor's Practice in Cardiology
Daugavpils, LV-5401, Latvia
SIA ARI Med
Daugavpils, LV-5401, Latvia
Daugavpils Regional Hospital
Daugavpils, LV-5417, Latvia
Rutas Eglites GP Practice
Kuldīga, LV-3301, Latvia
Liepaja Regional Hospital
Liepāja, LV-3414, Latvia
Lija Mora physician practice
Ogre, LV-5001, Latvia
1st Riga Clinical Hospital
Riga, LV-1001, Latvia
P. Stradins Clinical University Hospital
Riga, LV-1002, Latvia
Health Center Adoria
Riga, LV-1011, Latvia
Health Center 4
Riga, LV-1012, Latvia
Riga East Clinical University Hospital "Gailezers"
Riga, LV-1038, Latvia
APS Clinic
Riga, LV-1050, Latvia
Vidzemes Hospital
Valmiera, LV-4201, Latvia
Gita Rancane - cardiology private practice
Ventspils, LV-3601, Latvia
Mariu klinika JSC
Kaunas, 45462, Lithuania
LUHS Kauno Hospital (Laisves ave.)
Kaunas, LT-44320, Lithuania
LUHS Kauno Hospital (Josvainiu str.)
Kaunas, LT-47144, Lithuania
Kardiolitos klinikos / BMP
Kaunas, LT-49287, Lithuania
Saules family medicine center
Kaunas, LT-49449, Lithuania
Hospital of LT University of Health Sciences Kaunas Clinics
Kaunas, LT-50161, Lithuania
InMedica clinic Zaliakalnis
Kaunas, LT-50177, Lithuania
Kardiologijos ir reabilitacijos klinika
Klaipėda, LT-91131, Lithuania
Klaipeda Republican Hospital
Klaipėda, LT-92231, Lithuania
Klaipeda Seamen's Hospital Cardiology Department I
Klaipėda, LT-92288, Lithuania
Klaipedos Jurininku Ligonine
Klaipėda, LT-92288, Lithuania
Siauliai Republican hospital
Šiauliai, 76231, Lithuania
InMedica Clinic Santariskes
Vilnius, LT-08431, Lithuania
Vilnius University Hospital Santaros Klinikos
Vilnius, LT-08661, Lithuania
Hospital Sultanah Bahiyah
Alor Star, 5460, Malaysia
University Hospital Kebangsaan Malaysia
Cheras, 56000, Malaysia
Hospital Sultanah Aminah
Johor Bahru, 80100, Malaysia
Hospital Raja Perempuan Zainab II
Kelantan, 15200, Malaysia
Hospital Universiti Sains Malaysia
Kelantan, TBC, Malaysia
Institute Jantung Negara
Kuala Lumpur, 50400, Malaysia
University Malaya Medical Centre
Kuala Lumpur, 59100, Malaysia
Hospital Tengku Ampuan Afzan
Kuala Pahang, 25100, Malaysia
Hospital Al-Sultan Abdullah (UiTM Hospital)
Kuala Selangor, 42300, Malaysia
Hospital Serdang
Kuala Selangor, 43000, Malaysia
Hospital Sultan Abdul Aziz Shah
Kuala Selangor, 43400, Malaysia
Hospital Seberang Jaya
Pulau Pinang, 13700, Malaysia
Sarawak General Hospital
Sarawak, 93400, Malaysia
Sarawak Heart Centre
Sarawak, 94300, Malaysia
Seremban Hospital Neurology
Seremban, 70300, Malaysia
Admiraal de Ruyterziekenhuis
Goes, Zeeland, 4462RA, Netherlands
Ziekenhuis Amstelland
Amstelveen, 1186 AM, Netherlands
Amsterdam UMC | Heart Centre - Curius Research Department
Amsterdam, 1105 AZ, Netherlands
Gelre Apeldoorn Ziekenhuizen | Cardiology Department
Apeldoorn, 7334 DZ, Netherlands
Rijnstate | Arnhem - Cardiology Department - Cardio Research
Arnhem, 6815 AD, Netherlands
Rode Kruis Ziekenhuis
Beverwijk, 1942 LE, Netherlands
Tergooiziekenhuizen-Blaricum
Blaricum, 1261 AN, Netherlands
Amphia Breda | Department of Cardiology, BMC Research
Breda, 4818 CK, Netherlands
The Van Weel-Bethesda Hospital | Research Department
Dirksland, 3247 BW, Netherlands
Albert Schweitzer Ziekenhuis | Dordwijk - Cardiology Department
Dordrecht, 3318 AT, Netherlands
Catharina Hospital | Cardiology Department
Eindhoven, 5623 EJ, Netherlands
Treant locatie Scheper
Emmen, 7824 AA, Netherlands
Medisch Spectrum Twente | Thorax Centrum Twente - Foundation Cardiovascular Research and Education Enschede
Enschede, 7611 JH, Netherlands
Rivas | Beatrix Hospital Gorinchem - Cardiology Department
Gorinchem, 4204 AA, Netherlands
Universitair Medisch Centrum Groningen
Groningen, 9713 GZ, Netherlands
Martini Ziekenhuis, Locatie van Swieten
Groningen, 9728 NT, Netherlands
Spaarne Gasthuis | Haarlem Zuid - Cardiology
Haarlem, 2035 RC, Netherlands
Saxenburgh Medisch Centrum | Cardiology Department
Hardenberg, 7772 SE, Netherlands
Bravis Ziekenhuis | Roosendaal - Cardiology Department
Roosendaal, 4708 AE, Netherlands
Medisch Centrum Haaglanden, Locatie Westeinde
The Hague, 2512 VA, Netherlands
HagaZiekenhuis | Cardiology Department
The Hague, 2545 AA, Netherlands
Ziekenhuis Rivierenland | Cardiology Research Department
Tiel, 4002 WP, Netherlands
VieCuri - Medisch Centrum voor Noord-Limburg locatie Venlo
Venlo, 5912 BL, Netherlands
Zaans Medisch Centrum | Hartvaatcentrum
Zaandam, 1502 DV, Netherlands
Ålesund Sykehus, Kardiologisk Seksjon
Ålesund, 6026, Norway
Nordlandssykehuset Bodø Cardio
Bodø, 8092, Norway
Vestre Viken HF - Drammen Sykehus Cardiology
Drammen, 3004, Norway
Sykehuset Innlandet HF Elverum
Elverum, 2409, Norway
Sykehus Østfold Kalnes Cardio
Fredrikstad, NO-1603, Norway
Vestre Viken HF - Bærum Sykehus Cardiology
Gjettum, 1346, Norway
Sykehuset i Gjøvik Medisinsk
Gjøvik, 2819, Norway
UNN Harstad Medisinsk avdeling
Harstad, 9406, Norway
Sykehuset Lillehammer Medicine
Lillehammer, 2609, Norway
Molde Sjukehus Medisinsk
Molde, 6407, Norway
Akershus University Hospital Cardiology Department
Nordbyhagen, 1478, Norway
Rikshospitalet Cardiology
Oslo, 27, Norway
Diakonhjemmets sykehus
Oslo, 319, Norway
OUS Ullevål Cardiology
Oslo, 450, Norway
Skedsmo Medisinske Senter
Skedsmokorset, 2020, Norway
Stavanger UHospital Cardiology
Stavanger, 4011, Norway
UNN Tromsø Cardiology Dep.
Tromsø, 9038, Norway
Uniwersytecki Szpital Kliniczny w Bialymstoku
Bialystok, 15-276, Poland
KLIMED Marek Klimkiewicz
Bialystok, 15-704, Poland
MICS Centrum Medyczne Bydgoszcz
Bydgoszcz, 85-065, Poland
Centrum Medyczne KerMed
Bydgoszcz, 85-231, Poland
Uniwersyteckie Centrum Kliniczne
Gdansk, 80-214, Poland
Samodzielny Publiczny Specjalistyczny Szpital Zachodni
Grodzisk Mazowiecki, 05 825, Poland
CLINICAL MEDICAL RESEARCH Sp. z o. o.
Katowice, 40-156, Poland
Vita Longa Sp. z o.o.
Katowice, 40-748, Poland
Unicardia Specjalistyczne Centrum Leczenia Ch.Serca i Naczyn
Krakow, 31-271, Poland
Centrum Terapii Wspolczesnej
Lodz, 90-338, Poland
CM MED-GASTR Sp. z o.o.
Lodz, 91-034, Poland
Centrum Medyczne Ogrodowa G. i M. Kania Lekarze i Lekarze Dentysci Spólka Partnerska z siedziba w Skierniewicach
Lowicz, 99-400, Poland
1 Wojskowy Szpital Kliniczny z Poliklinika SPZOZ w Lublinie
Lublin, 20-049, Poland
NZOZ "Twoja Przychodnia" Sp. z o.o.
Lublin, 20-857, Poland
Futuremeds sp. z o. o.
Olsztyn, 10-010, Poland
Etyka Osrodek Badan Klinicznych
Olsztyn, 10-117, Poland
NZOZ Heureka
Piaseczno, 05-500, Poland
Irmed Klimkiewicz, Rudziewicz-Kowalska Sp.j.
Piotrkow Trybunalski, 97-300, Poland
Solumed Centrum Medyczne
Poznan, 60-529, Poland
Velocity Pulawy
Puławy, 24-100, Poland
EMED Centrum Uslug Medycznych
Rzeszów, 35-205, Poland
ClinMedica Research Sp. z o.o.
Skierniewice, 96-100, Poland
"Nowe Zdrowie-Ck" Kieltucki I Wspolnicy Spolka Jawna
Staszów, 28-200, Poland
NBR Polska Tomasz Klodawski
Warsaw, 00-465, Poland
Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji
Warsaw, 02-637, Poland
KO-MED Centra Kliniczne Zamosc
Zamość, 22-400, Poland
Hospital da Senhora da Oliveira | Clinical Research Department
Guimaraes, Braga, Braga District, 4835-044, Portugal
Centro Hospitalar Universitario Cova de Beira | Clinical Research Department
Covilha, Castelo Branco District, 6200-251, Portugal
Luz Saude | Hospital da Luz Lisboa - Centro de Investigacao Clinica
Lisbon, Lisbon District, 1500-650, Portugal
Centro Hospitalar Universitario de Lisboa Norte | Heart and Vessels Department
Lisbon, Lisbon District, 1649-035, Portugal
Hospital de Vila Franca de Xira | Centro de Desenvolvimento e Investigacao
Vila Franca de Xira, Lisbon District, 2600-009, Portugal
Hospital Pedro Hispano | Clinical Research Center
Matosinhos Municipality, Porto District, 4464-513, Portugal
Ucardio | Cardiology Department
Riachos, Santarém District, 2350-325, Portugal
Hospital Garcia de Orta | Research Department
Almada, Setúbal District, 2805-267, Portugal
Centro Clinico Academico Braga | Braga, Portugal
Braga, 4710-243, Portugal
Centro Hospitalar e Universitario de Coimbra, E.P.E. | Department of Cardiology, Research Unit
Coimbra, 3004-561, Portugal
Centro Hospitalar de Tamega e Sousa | Hospital Padre Americo - Cardiology Department
Guilhufe, 4564-007, Portugal
Centro Hospitalar de Leiria | Santo Andre Hospital - Research Center
Leiria, 2410-197, Portugal
Centro Hospitalar de Lisboa Ocidental | Clinical Research Department
Lisbon, 1449-005, Portugal
Lusiadas | Hospital Lusiadas Lisboa - Lusiadas Knowledge Center
Lisbon, 1500-458, Portugal
Centro Hospitalar Universitario de Sao Joao | Polo Porto - Centro de Investigacao e Ensaios Clinicos
Porto, 4200-319, Portugal
Centro Hospitalar Vila Nova de Gaia e Espinho | Unit 1 - Clinical Research Center
Porto, 4434-502, Portugal
Luz Saude | Hospital da Luz Setubal - Clinical Research Department
Setúbal, 2900-722, Portugal
Centro Hospitalar De Tras os Montes e Alto Douro | Hospital Sao Pedro - Centro de Investigacao Clinica
Vila Real, 5000-508, Portugal
Cardiomed S.R.L
Cluj-Napoca, Dolj, 400015, Romania
CMI. Dr. Podoleanu Cristian
Târgu Mureş, Mureș County, TBC, Romania
Municipal Clinical Emergency Hospital of Timisoara
Timișoara, Timiș County, 300254, Romania
Sp. Judetean de Urgenta Dr. Constantin Opris Baia Mare
Baia Mare, 430031, Romania
S.C Thera Card S.R.L
Brasov, 500102, Romania
S.C. Centrul Medical de Diagnostic si Tratament Ambulator Neomed SRL
Brasov, 500283, Romania
Emergency County Hospital, Braila
Brăila, 810318, Romania
Spitalul Clinic Colentina
Bucharest, 20125, Romania
Emergency Institute for Cardiovascular Diseases
Bucharest, 22322, Romania
Spitalul Clinic de Urgenta Sf. Ioan
Bucharest, 42122, Romania
Spitatul Universitar de Urgenta Bucaresti
Bucharest, 50098, Romania
Niculae Stancioiu Heart Institute Cluj-Napoca
Cluj-Napoca, 400001, Romania
Spitalul Clinic de Recuperare Cluj-Napoca
Cluj-Napoca, 400300, Romania
Sfantul Spiridon Emergency Clinical County Hospital
Iași, 700111, Romania
S.C. CARDIOMED S.R.L. Iasi
Iași, 700732, Romania
S.C. Sal Med SRL
Piteşti, TBC, Romania
Spitalul Judetean de Urgenta Satu Mare
Satu Mare, 440192, Romania
Spitalul de urgenta Sf. Ioan Cel Nou
Suceava, 720237, Romania
S.C. Cardio Med S.R.L.
Târgu Mureş, 540124, Romania
Emergency Institute of Cardiovascular Diseases & Transplant
Târgu Mureş, 540136, Romania
Timisoara Institute of Cardiovascular Diseases
Timișoara, 300310, Romania
National University Hospital
Singapore, 119074, Singapore
National Heart Centre Singapore
Singapore, 169609, Singapore
Tan Tock Seng Hospital
Singapore, 308433, Singapore
SingHealth Polyclinics - Pasir Ris
Singapore, 519457, Singapore
Changi General Hospital
Singapore, 529889, Singapore
Sengkang General Hospital
Singapore, 544886, Singapore
Ng Teng Fong General Hospital
Singapore, 609606, Singapore
ALIAN s.r.o.
Bardejov, 085 01, Slovakia
GALENUM s.r.o.
Bratislava, 821 07, Slovakia
Kardiosanus | Bratislava, Slovakia
Bratislava, 84107, Slovakia
Nemocnica s poliklinikou Brezno, n.o.
Brezno, 977 01, Slovakia
KARDIO R s.r.o.
Košice, 040 11, Slovakia
Medical Group Kosice s.r.o. | Kosice, Slovakia
Košice, 04001, Slovakia
KARDIO-ANGIO s.r.o.
Levice, 93401, Slovakia
KardioLEV s.r.o.
Levoča, 05401, Slovakia
Internal and Diabetes Clinic - IN-DIA s.r.o. | Lucenec, Slovakia
Lučenec, 984 01, Slovakia
KardioMed | Outpatient Cardiology and Internal Medicine II Clinic
Lučenec, 984 01, Slovakia
KARDIO 1 | Lucenec, Slovakia
Lučenec, 98401, Slovakia
ORALEK, s.r.o.
Námestovo, 02901, Slovakia
Kardiocentrum Nitra | Cardiology Clinic - Outpatient Department
Nitra, 949 01, Slovakia
Specializovana nemocnica sv. Svorada Zobor, n.o.
Nitra, 949 88, Slovakia
KaCH, s.r.o.
Nové Zámky, 940 02, Slovakia
BENIMED s.r.o.
Piešťany, 92101, Slovakia
Medikard | Department of Internal Medicine
Prešov, 08001, Slovakia
MEDISPOL s.r.o.
Prešov, 08001, Slovakia
Interna SK s.r.o.
Svidník, 08901, Slovakia
Kardiologicka ambulancia Trnava, MUDr. Vladimir Macek
Trnava, 91701, Slovakia
Medivasa s.r.o.
Žilina, 01001, Slovakia
Pusan National University Hospital
Busan, Busan Gwang''yeogsi, 49241, South Korea
Kyungpook National University Hospital
Daegu, Daegu Gwang''yeogsi, 41944, South Korea
Yonsei University Wonju Christian Hospital
Wŏnju, Gang''weondo, 26426, South Korea
Hallym University Sacred Heart Hospital
Anyang-si, Gyeonggido, 14068, South Korea
Bundang Cha Hospital
Seongnam-si, Gyeonggido, 13496, South Korea
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggido, 13620, South Korea
The Catholic University of Korea Seoul St. Mary's Hospital
Seoul, Gyeonggido, 137-701, South Korea
Ajou University Hospital
Suwon, Gyeonggido, 443-721, South Korea
Uijeongbu ST. Mary's Hospital
Uijeongbu-si, Gyeonggi-do, Gyeonggido, 11765, South Korea
The Catholic Univ. of Korea Eunpyeong St. Mary's Hospital
Seoul, Seoul Teugbyeolsi, 03312, South Korea
Seoul National University Hospital
Seoul, Seoul Teugbyeolsi, 3080, South Korea
Dong-A University Hospital
Busan, 49201, South Korea
Keimyung University Dongsan Medical Center
Daegu, 42601, South Korea
Chonnam National University Hospital
Gwangju, 501-757, South Korea
Gachon University Gil Medical Center
Incheon, 21565, South Korea
Korea University Anam Hospital
Seoul, 02841, South Korea
Severance Hospital, Yonsei University Health System
Seoul, 03722, South Korea
Asan Medical Center
Seoul, 138-736, South Korea
Chung-Ang University Hospital
Seoul, 156-755, South Korea
Samsung Medical Center
Seoul, 6351, South Korea
Complejo Hospitalario Universitario de Ferrol | Hospital Naval - Unidad de Hipertensión Arterial
Ferrol, A Coruña, 15405, Spain
Hospital Clinico Universitario de Santiago de Compostela | Cardiology Department
Santiago de Compostela, A Coruña, 15706, Spain
Hospital Universitari de Bellvitge | Bellvitge Biomedical Research Institute - Cardiology - AF, Stroke Prevention
L'Hospitalet de Llobregat, Barcelona, 08907, Spain
Jose Manuel Pascual Pascual S.A. | Hospital Virgen del Camino - Internal Medicine Department
Sanlúcar de Barrameda, Cádiz, 11540, Spain
Jose Manuel Pascual Pascual S.A. | Hospital Virgen de las Montanas - Internal Medicine Department
Villamartín, Cádiz, 11650, Spain
Hospital Universitario de La Princesa | Internal Medicine Department
Madrid, Madrid [es-m], 28006, Spain
Hospital Universitario Virgen de la Victoria | Cardiology Department
Málaga, Málaga, 29010, Spain
Hospital Universitario Central de Asturias | Servicio de Cardiologia
Oviedo, Principality of Asturias, 33006, Spain
Hospital Alta Resolucion de Lebrija | Cardiology Service Department
Lebrija, Sevilla, 41740, Spain
Hospital Alta Resolucion de Utrera | Cardiology Service Department
Utrera, Sevilla, 41710, Spain
University Hospital of A Coruna | Cardiology department
A Coruña, 15006, Spain
Hospital General Universitario Doctor Balmis de Alicante | Cardiology Department
Alicante, 03010, Spain
Hospital de la Santa Creu i Sant Pau | Cardiology Department
Barcelona, 08025, Spain
Vall d'Hebron Barcelona Hospital Campus | Vall d'Hebron Hospital Universitario - Cardiology Department
Barcelona, 08035, Spain
Hospital Quironsalud Barcelona | Internal Medicine Department
Barcelona, 8023, Spain
Hospital Universitario Ramon y Cajal | Departamento de Medicina Interna
Madrid, 28034, Spain
Hospital Universitario 12 de Octubre | Cardiology Department
Madrid, 28041, Spain
Hospital Universitario La Paz | Cardiology Department - AF, Stroke Prevention
Madrid, 28046, Spain
Hospital Universitario La Paz | IdiPAZ - Neurology Department
Madrid, 28046, Spain
Hospital Clinico Universitario Virgen de la Arrixaca | Cardiology Department
Murcia, 30120, Spain
Hospital Universitario Virgen del Rocio | Hospital General - Departamento de Cardiologia y Cirugia Cardiovascular
Seville, 41013, Spain
Hospital General Universitario de Valencia | Cardiology Department
Valencia, 46014, Spain
La Fe University and Polytechnic Hospital | Cardiology Department
Valencia, 46026, Spain
Södra Älvsborgs Sjukhus
Borås, 501 82, Sweden
Falu Lasarett
Falun, 791 82, Sweden
SU/Östra
Gothenburg, 416 85, Sweden
Helsingborgs Lasarett
Helsingborg, TBC, Sweden
Universitetssjukhuset i Linköping
Linköping, 581 85, Sweden
Clemenstorget Hjärtmottagning
Lund, 222 21, Sweden
Skånes Universitetssjukhus
Lund, 222 42, Sweden
SU/Mölndal
Mölndal, 431 80, Sweden
Vrinnevisjukhuset
Norrköping, 601 82, Sweden
Universitetssjukhuset Örebro
Örebro, 701 85, Sweden
Skellefteå Lasarett
Skellefteå, 931 86, Sweden
Södersjukhuset AB
Stockholm, 118 83, Sweden
Karolinska Universitetssjukhuset Huddinge Stockholm
Stockholm, 141 86, Sweden
Karolinska Universitetssjukhuset
Stockholm, 171 76, Sweden
Danderyds sjukhus
Stockholm, 182 88, Sweden
Norrlands Universitetssjukhus, Umea
Umeå, 901 85, Sweden
Akademiska Sjukhuset
Uppsala, TBC, Sweden
Västmanlands Sjukhus Västerås
Västerås, 721 89, Sweden
Kantonsspital Aarau
Aarau, Canton of Aargau, 5001, Switzerland
Kantonsspital Baden
Baden, Canton of Aargau, 5404, Switzerland
Universitätsspital Basel
Basel, Canton of Basel-City, 4056, Switzerland
Kantonsspital St. Gallen
Sankt Gallen, Canton of St. Gallen, 1009, Switzerland
Inselspital Universitätsspital Bern
Bern, 3010, Switzerland
Cardiocentro Ticino
Lugano, 6900, Switzerland
UniversitätsSpital Zürich
Zurich, 8091, Switzerland
National Yang Ming Chiao Tung University Hospital
Yilan, Ilan, 260006, Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, Kaohsiung, 807377, Taiwan
Chi Mei Medical Center
Taikang, Tainan, 71004, Taiwan
MacKay Memorial Hospital Tamsui Branch
New Taipei City, Taipei, 25160, Taiwan
Shin Kong Wu Ho-Su Memorial Hospital
Taipei, Taipei, 111, Taiwan
Taipei Municipal Wanfang Hospital
Taipei, Taipei, 116, Taiwan
Changhua Christian Hospital
Changhua, 50006, Taiwan
Mackay Memorial Hospital - Hsinchu Branch
Hsinchu, 300, Taiwan
Buddhist Tzu-Chi General Hospital, Hualien
Hualien City, 970, Taiwan
Veterans General Hospital
Kaohsiung City, 813414, Taiwan
E-Da Hospital
Kaohsiung City, 82445, Taiwan
Chang Gung Memorial Hospital Kaohsiung
Kaohsiung City, 833, Taiwan
Chung Shan Medical University Hospital
Taichung, 402306, Taiwan
China Medical University Hospital
Taichung, 404327, Taiwan
Taichung Veterans General Hospital
Taichung, 40705, Taiwan
National Cheng Kung University Hospital
Tainan, 704, Taiwan
National Taiwan University Hospital
Taipei, 100, Taiwan
Mackay Memorial Hospital
Taipei, 104, Taiwan
Cathay General Hospital
Taipei, 106, Taiwan
Taipei Medical University | Clinical Research Center
Taipei, 110, Taiwan
Taipei Veterans General Hospital
Taipei, 11217, Taiwan
Tri-Service General Hospital
Taipei, 114, Taiwan
Chang Gung Memorial Hospital at Linkou
Taoyuan District, 33305, Taiwan
Afyonkarahisar Saglik Bilimleri Universitesi
Afyonkarahisar, 3218, Turkey (Türkiye)
Baskent Universitesi Tip Fakultesi Hastanesi
Ankara, 6490, Turkey (Türkiye)
Health Ministry Of Türkiye Republic Ankara Bilkent City Hospital
Ankara, 6800, Turkey (Türkiye)
Akdeniz Universitesi Tip Fakultesi Hastanesi
Antalya, 7059, Turkey (Türkiye)
Hitit Universitesi Tip Fakultesi
Çorum, 19030, Turkey (Türkiye)
Ataturk Universitesi Tip Fakultesi
Erzurum, 25240, Turkey (Türkiye)
Eskisehir Osmangazi Universitesi Tip Fakultesi
Eskişehir, 26480, Turkey (Türkiye)
Istanbul Universitesi Cerrahpasa - Kardiyoloji Anabilim Dali
Istanbul, 34098, Turkey (Türkiye)
Marmara Uni. Tip Fak. Pendik EAH Kardiyoloji
Istanbul, 34899, Turkey (Türkiye)
Istanbul Mehmet Akif Ersoy Gogus Kalp Damar Cerrahisi E.A.H.
Istanbul, TBC, Turkey (Türkiye)
Dokuz Eylul Universitesi Tip Fakultesi
Izmir, 35100, Turkey (Türkiye)
Izmir Ekonomi Universitesi Medikal Point Hastanesi
Izmir, 35575, Turkey (Türkiye)
Erciyes Universitesi Tip Fakultesi
Kayseri, 38039, Turkey (Türkiye)
Kocaeli Universitesi Tip Fakultesi
Kocaeli, 41380, Turkey (Türkiye)
Kutahya Saglik Bilimleri Uni. Evliya Celebi Egitim ve Arasti
Kütahya, 43040, Turkey (Türkiye)
Adana Sehir Egitim ve Arastirma Hastanesi
Medreseboğazı, 1370, Turkey (Türkiye)
Saglik Bilimleri Univ. Samsun EAH Kardiyoloji Departmani
Samsun, 55090, Turkey (Türkiye)
Staploe Medical Centre
Ely, Cambridgeshire, CB7 5SQ, United Kingdom
Countess of Chester Hospital
Chester, Cheshire, CH2 1UL, United Kingdom
Chesterfield Royal Hospital
Chesterfield, Derbyshire, S44 5BL, United Kingdom
Torbay Hospital
Torbay, Devon, TQ2 7AA, United Kingdom
Poole Hospital NHS Trust
Poole, Dorset, BH15 2JB, United Kingdom
Glasgow Royal Infirmary | Stroke Unit
Glasgow, Glasgow City, G4 0SF, United Kingdom
North Hampshire Hospital
Basingstoke, Hampshire, RG24 9NA, United Kingdom
Lister Hospital
Stevenage, Hertfordshire, SG1 4AB, United Kingdom
Queen Elizabeth the Queen Mother Hospital
Margate, Kent, CT9 4AN, United Kingdom
University Hospitals Leicester
Leicester, Leicestershire, LE3 9QP, United Kingdom
Northwick Park Hospital
Harrow, London, HA1 3UJ, United Kingdom
Charing Cross Hospital
London, London, W6 8RF, United Kingdom
Craigavon Area Hospital
Craigavon, North Ireland, BT63 5QQ, United Kingdom
Wansbeck General Hospital
Ashington, Northumberland, NE63 9JJ, United Kingdom
Freeman Hospital
Newcastle, Tyne and Wear, NE7 7DN, United Kingdom
Soho Health Centre, Future Meds
Birmingham, West Midlands, B21 9RY, United Kingdom
Russells Hall Hospital
Dudley, West Midlands, DY1 2HQ, United Kingdom
St Richard's Hospital
Chichester, West Sussex, PO19 6SE, United Kingdom
Worcestershire Acute Hospital Trust
Worcester, Worcestershire, WR5 1DD, United Kingdom
James Cook University Hospital South Tees
Middlesbrough, Yorkshire, TS43BW, United Kingdom
Ely Bridge Medical Centre
Cardiff, CF5 4AD, United Kingdom
Heart and Chest Hospital
Liverpool, L14 3PE, United Kingdom
King's College Hospital - NHS Foundation Trust
London, SE5 9RS, United Kingdom
Future Meds - Bromborough
Metropolitan Borough of Wirral, CH62 6EE, United Kingdom
Related Publications (2)
Alexander JH, Lydon EJ, Piccini JP, Viethen T, Oldgren J, Goodman SG, Steffel J, Russo AM, van Gelder IC, Ferdinand KC, Lopes RD, Mundl H, Benczur B, Gomez-Doblas JJ, Glikson M, Goudev A, Grove EL, Halvorsen S, Kiviniemi T, Martin AC, Sandhu RK, Vinereanu D, Rockhold FW, Caso V, Coppolecchia R, Patel MR. Asundexian or Apixaban in Patients With Atrial Fibrillation According to Prior Oral Anticoagulant Use: A Subgroup Analysis of the OCEANIC-AF Randomized Clinical Trial. JAMA Cardiol. 2025 Jun 1;10(6):555-563. doi: 10.1001/jamacardio.2025.0277.
PMID: 40136309DERIVEDPiccini JP, Patel MR, Steffel J, Ferdinand K, Van Gelder IC, Russo AM, Ma CS, Goodman SG, Oldgren J, Hammett C, Lopes RD, Akao M, De Caterina R, Kirchhof P, Gorog DA, Hemels M, Rienstra M, Jones WS, Harrington J, Lip GYH, Ellis SJ, Rockhold FW, Neumann C, Alexander JH, Viethen T, Hung J, Coppolecchia R, Mundl H, Caso V; OCEANIC-AF Steering Committee and Investigators. Asundexian versus Apixaban in Patients with Atrial Fibrillation. N Engl J Med. 2025 Jan 2;392(1):23-32. doi: 10.1056/NEJMoa2407105. Epub 2024 Sep 1.
PMID: 39225267DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Therapeutic Area Head
- Organization
- Bayer AG
Publication Agreements
- PI is Sponsor Employee
- No
- Restriction Type
- OTHER
- Restrictive Agreement
- Yes
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 30, 2022
First Posted
December 8, 2022
Study Start
December 5, 2022
Primary Completion
January 31, 2024
Study Completion
January 31, 2024
Last Updated
December 9, 2024
Results First Posted
December 9, 2024
Record last verified: 2024-12
Data Sharing
- IPD Sharing
- Will not share
Availability of this study's data will later be determined according to Bayer's commitment to the EFPIA/PhRMA "Principles for responsible clinical trial data sharing". This pertains to scope, timepoint and process of data access. As such, Bayer commits to sharing upon request from qualified researchers patient-level clinical trial data, study-level clinical trial data, and protocols from clinical trials in patients for medicines and indications approved in the US and EU as necessary for conducting legitimate research. This applies to data on new medicines and indications that have been approved by the EU and US regulatory agencies on or after January 01, 2014. Interested researchers can use www.vivli.org to request access to anonymized patient-level data and supporting documents from clinical studies to conduct research. Information on the Bayer criteria for listing studies and other relevant information is provided in the member section of the portal.