Comparison Between Right and Left Radial Approach in Patients Undergoing Percutaneous Coronary Procedures

NCT05626660 | Completed

• 1 other identifier: Coronary procedures
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Our aim is to compare between right and left radial approach in patients undergoing percutaneous coronary procedures regarding feasibility and complications.

Conditions

Coronary Artery Disease

Outcome Measures

Primary Outcomes (4)

• Comparison between right and left radial approach in patients undergoing percutaneous coronary Procedures , is there is difference in tortuosity of the radial and subclavian arteries between both approaches ?

  To compare the incidence of tortuosity in the radial and subclavian arteries between the right vs left radial approach. .

  Baseline

• Comparison between right and left radial approach in patients undergoing percutaneous coronary Procedures regarding easiness of cannulation of left main coronary artery and right coronary artery tortuosity by assessing time needed for cannulation

  To compare the easiness of cannulation of left main (LM ) coronary artery and right coronary artery (RCA) via the two approaches by assessing time needed by the guiding wire and catheter to reach the ostia of either the left main coronary artery and right coronary artery .

  baseline

• Comparison between right and left radial approach in patients undergoing percutaneous coronary Procedures , is there is possible difference in the incidence of complications via the two approaches?

  To compare the incidence of complications e.g (bleeding , pseudoaneurysm formation ,e.t.c ) between the right and left radial approaches .

  baseline

• Comparison between right and left radial approach in patients undergoing percutaneous coronary Procedures regarding the incidence of crossover between right and left radial approaches and between radial and femoral approach .

  To compare the incidence of crossover between right and left radial arteries and femoral approach in case of marked radial spasm .

  baseline

Study Arms (2)

Right Radial Group

Other: Coronary angiography and percutaneous coronary intervention

Left Radial Group

Other: Coronary angiography and percutaneous coronary intervention

Interventions

Coronary angiography and percutaneous coronary intervention OTHER

Coronary angiography and percutaneous coronary intervention via radial approach

Left Radial Group; Right Radial Group

Eligibility Criteria

• Age: 18 Years - 110 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients undergoing coronary angiography or elective PCI in assiut university heart hospital.

You may qualify if:

• All patients presented to assiut university cardiac catheterization laboratory and eligible for radial coronary procedures (either diagnostic or interventional )

You may not qualify if:

• Patients with acute coronary syndrome.
• Patients with chronic upper limb ischemia
• Patients with AV fistula
• Patients with severe renal impairment
• Failure to successfully cannulate the radial artery

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut University

Asyut, Asyut Governorate, Egypt

Location

Related Publications (10)

• Daralammouri Y, Nazzal Z, Mosleh YS, Abdulhaq HK, Khayyat ZY, Hamshary YE, Azamtta M, Ghanim A, Awwad F, Majadla S, Maree M, Hamaida J, Ismail Y. Distal Radial Artery Access in comparison to Forearm Radial Artery Access for Cardiac Catheterization: A Randomized Controlled Trial (DARFORA Trial). J Interv Cardiol. 2022 Jul 15;2022:7698583. doi: 10.1155/2022/7698583. eCollection 2022.

  PMID: 35911661 BACKGROUND

• Kiemeneij F. Left distal transradial access in the anatomical snuffbox for coronary angiography (ldTRA) and interventions (ldTRI). EuroIntervention. 2017 Sep 20;13(7):851-857. doi: 10.4244/EIJ-D-17-00079.

  PMID: 28506941 BACKGROUND

• Lee OH, Roh JW, Im E, Cho DK, Jeong MH, Choi D, Kim Y. Feasibility and Safety of the Left Distal Radial Approach in Percutaneous Coronary Intervention for Bifurcation Lesions. J Clin Med. 2021 May 19;10(10):2204. doi: 10.3390/jcm10102204.

  PMID: 34069701 BACKGROUND

• Klimek K, Swiatek M, Klocek K, Tworek M, Zwolski M, Milewski K, Janas A. Comparison of Safety and Efficiency between Tiger-2 Catheter with Right Radial Artery Access and Judkins Catheter with Left Radial Artery Access. J Clin Med. 2021 Sep 6;10(17):4020. doi: 10.3390/jcm10174020.

  PMID: 34501468 BACKGROUND

• Burzotta F, Trani C, De Vita M, Crea F. A new operative classification of both anatomic vascular variants and physiopathologic conditions affecting transradial cardiovascular procedures. Int J Cardiol. 2010 Nov 5;145(1):120-2. doi: 10.1016/j.ijcard.2009.06.025. Epub 2009 Jul 17.

  PMID: 19616324 BACKGROUND

• Dehghani P, Mohammad A, Bajaj R, Hong T, Suen CM, Sharieff W, Chisholm RJ, Kutryk MJ, Fam NP, Cheema AN. Mechanism and predictors of failed transradial approach for percutaneous coronary interventions. JACC Cardiovasc Interv. 2009 Nov;2(11):1057-64. doi: 10.1016/j.jcin.2009.07.014.

  PMID: 19926044 BACKGROUND

• Kawamura Y, Yoshimachi F, Nakamura N, Yamamoto Y, Kudo T, Ikari Y. Impact of dedicated hemostasis device for distal radial arterial access with an adequate hemostasis protocol on radial arterial observation by ultrasound. Cardiovasc Interv Ther. 2021 Jan;36(1):104-110. doi: 10.1007/s12928-020-00656-4. Epub 2020 Mar 12.

  PMID: 32166728 BACKGROUND

• Abdelazeem B, Abuelazm MT, Swed S, Gamal M, Atef M, Al-Zeftawy MA, Noori MA, Lutz A, Volgman AS. The efficacy of nitroglycerin to prevent radial artery spasm and occlusion during and after transradial catheterization: A systematic review and meta-analysis of randomized controlled trials. Clin Cardiol. 2022 Dec;45(12):1171-1183. doi: 10.1002/clc.23906. Epub 2022 Nov 6.

  PMID: 36335609 BACKGROUND

• Kiemeneij F, Burzotta F, Fajadet J. Thirty years of transradial coronary interventions. EuroIntervention. 2022 May 15;18(1):19-21. doi: 10.4244/EIJ-E-22-00009. No abstract available.

  PMID: 35570688 BACKGROUND

• RADNER S. Thoracal aortography by catheterization from the radial artery; preliminary report of a new technique. Acta Radiol (Stockh). 1948 Feb 28;29(2):178-80. doi: 10.3109/00016924809132437. No abstract available.

  PMID: 18908938 BACKGROUND

MeSH Terms

Conditions

Coronary Artery Disease

Interventions

Percutaneous Coronary Intervention

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Intervention Hierarchy (Ancestors)

Endovascular Procedures; Vascular Surgical Procedures; Cardiovascular Surgical Procedures; Surgical Procedures, Operative; Minimally Invasive Surgical Procedures

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: November 3, 2022
• First Posted: November 25, 2022
• Study Start: November 15, 2022
• Primary Completion: December 15, 2024
• Study Completion: April 15, 2025
• Last Updated: June 4, 2025

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)