Implementation of an Enhanced Rehabilitation Protocol After Liver Transplantation: Feasibility and Analysis of Results

NCT05625139 | Completed

• 1 other identifier: 7906
• Study Type: observational
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

Currently, there are no expert recommendations regarding enhanced rehabilitation after liver transplantation. The development of Enhanced Rehabilitation After Surgery (ERAS) protocols in major surgery, particularly cardiothoracic surgery, has motivated some anesthesia teams to extubate liver transplant patients earlier who meet predefined criteria (young patient, absence of comorbidities, absence of intraoperative transfusion) in order to limit the occurrence of complications of mechanical ventilation (pneumopathies, tracheal wound, muscle loss, etc.) On the other hand, improved rehabilitation in this case was often synonymous with early extubation in the operating room. Few studies, on the other hand, relate the implementation of a complete rehabilitation protocol including pre-, intra- and postoperative guidelines.

Conditions

Liver Transplant Disorder

Keywords

Liver Transplant Disorder; Liver transplantation; ERAS

Outcome Measures

Primary Outcomes (1)

• Retrospective description of the protocol of improved rehabilitation after liver transplantation, to study the possibility of its implementation in the anesthesia-intensive care department and to analyze the first results

  Files analysed retrospectively from December 01, 2018 to August 31, 2020 will be examined

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Major subject operated at HUS for a liver transplant whose management was scheduled in the Surgical Intensive Care Unit fbetween December 01, 2018 and August 31, 2020

You may qualify if:

• Major subject operated at HUS for a liver transplant whose management was scheduled in the Surgical Intensive Care Unit fbetween December 01, 2018 and August 31, 2020
• Subject who does not question, after information, the reuse of his data for the purpose of this research

You may not qualify if:

• Subject having expressed his opposition to participate in the study
• Liver transplant patient hospitalized in the Medical Intensive Care Unit before or after the surgery

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service d'Anesthésie, Réanimation et Médecine péri-Opératoire - CHU de Strasbourg - France

Strasbourg, 67091, France

Location

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 14, 2022
• First Posted: November 22, 2022
• Study Start: September 14, 2020
• Primary Completion: September 14, 2021
• Study Completion: November 14, 2021
• Last Updated: October 31, 2023

Record last verified: 2022-11

Locations

FR (1)