Endometriosis Group Care

NCT05622955 | Completed Results

• 1 other identifier: 202206202
• Study Type: interventional
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to test the effectiveness of the Peer Empowered Endometriosis Pain Support (PEEPS) program in people living with endometriosis-related pelvic pain. The main question\[s\] it aims to answer are:

• Is PEEPS effective at decreasing pain interference and improving patient-reported quality of life outcomes?
• What are the barriers and facilitators to PEEPS implementation? Participants will engage in eight weekly 2-hour sessions led by an endometriosis specialist, pain psychologist, pelvic floor physical therapist, and yoga instructor. At these sessions they will participate in peer support, education, mindfulness, and yoga.

Conditions

Endometriosis; Pelvic Pain

Keywords

Group care; Integrative care; Pelvic floor physical therapy; Yoga; Mindfulness; Patient-centered outcomes

Outcome Measures

Primary Outcomes (1)

• PROMIS Pain Interference SF 8a

  Change in pain interference at completion of the intervention (8-weeks) as compared to baseline is reported. Analysis was conducted using mixed-effects modeling. PROMIS measures are reported with T-scores using a mean of 50 and a standard deviation (SD) of 10, based on the U.S. general population. Higher score indicates more of the measure (i.e. more pain).

  8 weeks

Secondary Outcomes (7)

• PROMIS Physical Function SF10a

  8 weeks

• Female Sexual Function Index

  8 weeks

• Endometriosis Health Profile-30

  8 weeks

• PROMIS Anxiety SF7a

  8 weeks

• PROMIS Depression SF8b

  8 weeks

Study Arms (1)

Endometriosis group care

EXPERIMENTAL

Groups of 6-10 patients with endometriosis and chronic pelvic pain will attend eight weekly two-hour sessions.

Other: Peer Empowered Endometriosis Pain Support (PEEPS)

Interventions

Peer Empowered Endometriosis Pain Support (PEEPS) OTHER

The sessions will provide education on endometriosis, mindfulness, yoga, nutrition, and strategies to cope with chronic pain. Patients will additionally receive peer and clinician support to decrease the social isolation experienced by people with endometriosis

Endometriosis group care

Eligibility Criteria

• Age: 18 Years - 48 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age 18-48 years
• Operative confirmation of endometriosis
• Chronic pelvic pain (defined as pain perceived to originate from the pelvis, lasting ≥6 months)
• No plan to have surgery in next 12 weeks
• Be able to attend eight 2-hour weekly sessions on the Washington University campus

You may not qualify if:

• Non-English speaking
• Currently pregnant
• Severe physical impairment
• History of hip or spine surgery
• Opioid use ≥ 5 days in the past 3 months, other than for the 6-week post-operative period
• Current or history of psychiatric disorder with psychosis
• Vulvadynia or vaginismus

Sponsors & Collaborators

• Washington University School of Medicine: lead
• National Institutes of Health (NIH): collaborator

Study Sites (1)

Washington University in St. Louis

St Louis, Missouri, 63110, United States

Location

Related Publications (57)

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MeSH Terms

Conditions

Endometriosis; Pelvic Pain

Condition Hierarchy (Ancestors)

Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Results Point of Contact

• Title: Whitney Ross
• Organization: WashU Medicine

ross.w@email.wustl.edu

314-747-5470

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 10, 2022
• First Posted: November 21, 2022
• Study Start: February 20, 2023
• Primary Completion: December 26, 2024
• Study Completion: September 26, 2025
• Last Updated: March 6, 2026
• Results First Posted: March 6, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)