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SARIpreSC2
Sponsor study identifier
observational
12,145
0 countries
N/A
Study Start
January 20, 2012
Actual (reported)Primary Completion
April 2, 2020
Actual (reported)Study Completion
April 2, 2020
Actual (reported)The Belgian Severe Acute Respiratory Infections network (BELSARI-net) was implemented during the influenza season 2011-2012 following the recommendations of the World Health Organization (WHO) to monitor severity of influenza viruses in hospitals. The network is composed of 6 hospitals throughout the country, two in each administrative region (Flanders, Wallonia and Brussels-Capital), and operates during the influenza epidemic period (from the last week of December or first/second week of January to the third/last week of April, depending on when influenza virus circulation is detected by the general population, based on the Influenza-like illness (ILI) network of general practitioners). Enrollment is performed for all cases matching the SARI case definition (based on WHO's case definition) and accepting to take part. A respiratory specimen is sampled systematically from each participant, and detailed clinico-epidemiological data, such as information on age, sex, symptoms and potential risk factors such as pregnancy or comorbidities (chronic respiratory diseases, asthma, chronic cardiovascular diseases, renal insufficiency, obesity, diabetes, hepatic or renal insufficiency, immunodeficiency, neuromuscular disease, pregnancy) is also collected. Participants are followed up during hospitalization for the occurrence of complications (detection of pneumonia based on chest radiography, development of acute respiratory distress syndrome (ARDS), requirement for respiratory assistance and/or for extracorporeal membrane oxygenation (ECMO), admission in intensive care unit (ICU)), or death (all-cause death). The current project includes all the samples received by the Belgian National Influenza Centre (NIC) during the influenza seasons 2011-2012 till 2019-2020.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 2, 2020
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 20, 2012
Actual (reported)April 2, 2020
Actual (reported)April 2, 2020
Actual (reported)November 9, 2022
Actual (reported)November 17, 2022
Actual (reported)Number of participants positive for influenza viruses
result of influenza PCR detection test (typing and subtyping)
within 10 days after symptom onset
Number of participants positive for non-influenza viruses
results of non-influenza multiplex PCR detection test (16 targets)
within 10 days after symptom onset (only routinely tested since influenza season 2015-2016)
Number of participants who died during hospitalization
alive or dead
from date of hospital admission until date of death during hospitalization or date of hospital exit
Number of participants with at least one known risk factor
on date of hospital admission
Number of participants who experienced at least one complication
from date of hospital admission until date of death during hospitalization or date of hospital exit
nasopharyngeal swab or nasal aspiration or broncho-alveolar lavage
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Patients admitted to one of the 6 participating hospital during the season surveillance dates.
Subissi L, Bossuyt N, Reynders M, Gerard M, Dauby N, Lacor P, Daelemans S, Lissoir B, Holemans X, Magerman K, Jouck D, Bourgeois M, Delaere B, Quoilin S, Van Gucht S, Thomas I, Barbezange C. Spotlight influenza: Extending influenza surveillance to detect non-influenza respiratory viruses of public health relevance: analysis of surveillance data, Belgium, 2015 to 2019. Euro Surveill. 2021 Sep;26(38):2001104. doi: 10.2807/1560-7917.ES.2021.26.38.2001104.
Fischer N, Dauby N, Bossuyt N, Reynders M, Gerard M, Lacor P, Daelemans S, Lissoir B, Holemans X, Magerman K, Jouck D, Bourgeois M, Delaere B, Quoilin S, Van Gucht S, Thomas I, Barbezange C, Subissi L. Monitoring of human coronaviruses in Belgian primary care and hospitals, 2015-20: a surveillance study. Lancet Microbe. 2021 Mar;2(3):e105-e114. doi: 10.1016/S2666-5247(20)30221-4. Epub 2021 Jan 27.
respiratory specimens (mainly nasopharyngeal swabs, but a few nasal aspirates and broncho-alveolar lavages)
12,145 participants (actual enrollment reported by the registry).
First Submitted
November 9, 2022
First Posted
November 17, 2022
Study Start
January 20, 2012
Actual (reported)Contact the study team to confirm eligibility.
Subissi L, Bossuyt N, Reynders M, Gerard M, Dauby N, Bourgeois M, Delaere B, Quoilin S, Van Gucht S, Thomas I, Barbezange C. Capturing respiratory syncytial virus season in Belgium using the influenza severe acute respiratory infection surveillance network, season 2018/19. Euro Surveill. 2020 Oct;25(39):1900627. doi: 10.2807/1560-7917.ES.2020.25.39.1900627.
Fischer N, Moreels S, Dauby N, Reynders M, Petit E, Gerard M, Lacor P, Daelemans S, Lissoir B, Holemans X, Magerman K, Jouck D, Bourgeois M, Delaere B, Quoilin S, Van Gucht S, Thomas I, Bossuyt N, Barbezange C. Influenza versus other respiratory viruses - assessing severity among hospitalised children, Belgium, 2011 to 2020. Euro Surveill. 2023 Jul;28(29):2300056. doi: 10.2807/1560-7917.ES.2023.28.29.2300056.
Primary Completion
April 2, 2020
Actual (reported)Study Completion
April 2, 2020
Actual (reported)Last Updated
September 8, 2023
Record last verified: 2023-09
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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