Performance of Pulmonary Embolism Risk Scores Out Come in CTPA Confirmed Patients

NCT05613855 | Unknown

• 1 other identifier: performance score outcome
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

1. 1.Assess performance of PERFORM score in predicting outcome in CTPA confirmed patients.
2. 2.Compare PERFORM score with the currently validated PESI in risk stratification of patients

Conditions

Pulmonary Embolism

Outcome Measures

Primary Outcomes (1)

• Assess performance of PERFORM score in predicting outcome in CTPA confirmed patients.

  from 11/2022 to 4/2024

Secondary Outcomes (1)

• Compare PERFORM score with the currently validated PESI in risk stratification of patients.

  from 11/2022 to 4/2024

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study will be on patients wh are above 18 years okd who are daignosed to have pulmonary embolism with CTPA

You may not qualify if:

• Patients who have contraindications for CTPA eg. Renal impairment
• Patients diagnosed and treated as PE without doing CTPA.
• Patients who refuse to participate in the study

Sponsors & Collaborators

• Assiut University: lead

Related Publications (6)

• Anderson FA Jr, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, Forcier A, Dalen JE. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med. 1991 May;151(5):933-8.

  PMID: 2025141 RESULT

• Kurkciyan I, Meron G, Sterz F, Janata K, Domanovits H, Holzer M, Berzlanovich A, Bankl HC, Laggner AN. Pulmonary embolism as a cause of cardiac arrest: presentation and outcome. Arch Intern Med. 2000 May 22;160(10):1529-35. doi: 10.1001/archinte.160.10.1529.

  PMID: 10826469 RESULT

• Jimenez D, Aujesky D, Moores L, Gomez V, Lobo JL, Uresandi F, Otero R, Monreal M, Muriel A, Yusen RD; RIETE Investigators. Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism. Arch Intern Med. 2010 Aug 9;170(15):1383-9. doi: 10.1001/archinternmed.2010.199.

  PMID: 20696966 RESULT

• Elias A, Mallett S, Daoud-Elias M, Poggi JN, Clarke M. Prognostic models in acute pulmonary embolism: a systematic review and meta-analysis. BMJ Open. 2016 Apr 29;6(4):e010324. doi: 10.1136/bmjopen-2015-010324.

  PMID: 27130162 RESULT

• Agnelli G, Becattini C. Acute pulmonary embolism. N Engl J Med. 2010 Jul 15;363(3):266-74. doi: 10.1056/NEJMra0907731. Epub 2010 Jun 30. No abstract available.

  PMID: 20592294 RESULT

• Yu S, Zhou H, Li Y, Song J, Shao J, Wang X, Xie Z, Qiu C, Sun K. PERFORM: Pulmonary embolism risk score for mortality in computed tomographic pulmonary angiography-confirmed patients. EClinicalMedicine. 2021 May 31;36:100897. doi: 10.1016/j.eclinm.2021.100897. eCollection 2021 Jun.

  PMID: 34136775 RESULT

MeSH Terms

Conditions

Pulmonary Embolism

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Embolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases

Central Study Contacts

Nourhan Safwat Abdelraheem, resiedent doctor

CONTACT

01067885766; nourhansafwat22@gmail.com

Suzan Salama Sayed, professor

CONTACT

01014236163; suzan.ahmed@med.au.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident doctor

Study Record Dates

• First Submitted: November 7, 2022
• First Posted: November 14, 2022
• Study Start: November 1, 2022
• Primary Completion: April 1, 2024
• Study Completion: April 1, 2024
• Last Updated: November 14, 2022

Record last verified: 2022-11