Assessment of Right Ventricular Function After Acute Pulmonary Embolism Using Speckle Tracking Echocardiography
1 other identifier
interventional
68
0 countries
N/A
Brief Summary
- 1.To asses regional RV function in patients presented with acute pulmonary embolism using speckle tracking echocardiography
- 2.To evaluate its relationship to long term mortality.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Dec 2020
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 26, 2020
CompletedFirst Posted
Study publicly available on registry
October 30, 2020
CompletedStudy Start
First participant enrolled
December 1, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2022
CompletedNovember 3, 2020
November 1, 2020
1 year
October 26, 2020
November 1, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
improve management of acute pulmonary embolism
comparison between speckle tracking echocardiograpgy and conventional echocardiography in pulmonary embolism
baseline
Study Arms (1)
patients with acute pulmonary embolism
EXPERIMENTALspeckle tracking echocardiography for patient with acute pulmonary embolism
Interventions
speckle tracking echocardiography of right ventricle
Eligibility Criteria
You may qualify if:
- clinical diagnosis of acute pulmonary embolism
- Age: 20 - 70 years.
You may not qualify if:
- coronary artery disease
- patient of Atrial fibrillation.
- Patient of impaired RV function due to chest disease (Cor-pulmonale)
- patient with impaired Ejection fraction (EF) \<50%
- Moderate to severe valvular heart disease.
- Atrio-ventricular conduction disturbance.
- Poor echogenicity
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (4)
Wendelboe AM, Raskob GE. Global Burden of Thrombosis: Epidemiologic Aspects. Circ Res. 2016 Apr 29;118(9):1340-7. doi: 10.1161/CIRCRESAHA.115.306841.
PMID: 27126645BACKGROUNDMcConnell MV, Solomon SD, Rayan ME, Come PC, Goldhaber SZ, Lee RT. Regional right ventricular dysfunction detected by echocardiography in acute pulmonary embolism. Am J Cardiol. 1996 Aug 15;78(4):469-73. doi: 10.1016/s0002-9149(96)00339-6.
PMID: 8752195BACKGROUNDFields JM, Davis J, Girson L, Au A, Potts J, Morgan CJ, Vetter I, Riesenberg LA. Transthoracic Echocardiography for Diagnosing Pulmonary Embolism: A Systematic Review and Meta-Analysis. J Am Soc Echocardiogr. 2017 Jul;30(7):714-723.e4. doi: 10.1016/j.echo.2017.03.004. Epub 2017 May 9.
PMID: 28495379BACKGROUNDTrivedi SJ, Altman M, Stanton T, Thomas L. Echocardiographic Strain in Clinical Practice. Heart Lung Circ. 2019 Sep;28(9):1320-1330. doi: 10.1016/j.hlc.2019.03.012. Epub 2019 Apr 12.
PMID: 31064715BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- doctor
Study Record Dates
First Submitted
October 26, 2020
First Posted
October 30, 2020
Study Start
December 1, 2020
Primary Completion
December 1, 2021
Study Completion
January 1, 2022
Last Updated
November 3, 2020
Record last verified: 2020-11