Surgery Versus Non-surgical Treatment for Esophageal Squamous Cell Carcinoma in Patients Older Than 70 Years

NCT05604950 | Completed

• 3 other identifiers: SCCH-TS2022No. 2020YFH0169No. 320.6750.2020-15-3
• Study Type: observational
• Target: 2
• Locations: 0 countries
• Sites: N/A

Brief Summary

To determine whether older patients who underwent esophagectomy had better outcome survival than those who were non-surgically treated.

Conditions

Esophageal Squamous Cell Carcinoma; Esophagectomy; Radiotherapy; Chemotherapy

Outcome Measures

Primary Outcomes (1)

• Selection of treatment modalities for elderly patients with oesophageal cancer

  Surgical data were retrospectively collected

  2009.01.01-2017.12.30

Study Arms (2)

S group

underwent surgical treatment.

Diagnostic Test: Since the data were collected retrospectively, there were no interventions

NS group

underwent non-surgical treatment with RT and/or chemoradiotherapy.

Diagnostic Test: Since the data were collected retrospectively, there were no interventions

Interventions

Since the data were collected retrospectively, there were no interventions DIAGNOSTIC_TEST

Since the data were collected retrospectively, there were no interventions

NS group; S group

Eligibility Criteria

• Age: 70 Years - 100 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Data were obtained from the Sichuan Cancer Hospital \& Institute Esophageal Cancer Case Management and the department of radiation oncology multicenter databases. We retrospectively analyzed esophageal squamous cell carcinoma patients who were 70 years or older, who underwent esophagectomy or radiotherapy/chemotherapy from January 2009 to December 2017. Patients were divided into two groups: surgery and non-surgery groups. We then prospectively collected data on 284 patients with esophageal squamous cell carcinoma in the Sichuan Cancer Hospital for results verification.

You may qualify if:

• Pathology confirmed ESCC,
• Patients with esophagectomy or radiotherapy (RT)/chemotherapy (CT),
• Age ≥ 70.

You may not qualify if:

• Having other malignant tumours,
• Missing of required data.

Sponsors & Collaborators

• Yongtao Han: lead

Related Publications (21)

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MeSH Terms

Conditions

Esophageal Squamous Cell Carcinoma

Condition Hierarchy (Ancestors)

Carcinoma, Squamous Cell; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms; Neoplasms, Squamous Cell; Esophageal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Head and Neck Neoplasms; Digestive System Diseases; Esophageal Diseases; Gastrointestinal Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 60 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Clinical Professor

Study Record Dates

• First Submitted: October 23, 2022
• First Posted: November 3, 2022
• Study Start: January 1, 2009
• Primary Completion: December 30, 2019
• Study Completion: October 1, 2022
• Last Updated: November 3, 2022

Record last verified: 2022-10