Key Insights

Highlights

Success Rate

85% trial completion

Published Results

11 trials with published results (3%)

Research Maturity

72 completed trials (22% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

4.0%

13 terminated out of 327 trials

Success Rate

84.7%

-1.8% vs benchmark

Late-Stage Pipeline

9%

30 trials in Phase 3/4

Results Transparency

15%

11 of 72 completed with results

Key Signals

11 with results85% success13 terminated

Data Visualizations

Phase Distribution

285Total
Not Applicable (32)
Early P 1 (2)
P 1 (57)
P 2 (164)
P 3 (28)
P 4 (2)

Trial Status

Unknown92
Recruiting85
Completed72
Not Yet Recruiting30
Active Not Recruiting25
Terminated13

Trial Success Rate

84.7%

Benchmark: 86.5%

Based on 72 completed trials

Clinical Trials (327)

Showing 20 of 20 trials
NCT07629817Phase 3RecruitingPrimary

Surgery vs. Radical Chemoradiotherapy for Esophageal SCC After Neoadjuvant Immunochemotherapy

NCT06304974Phase 3Active Not RecruitingPrimary

A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma(PANKU-Esophagus01)

NCT04543617Phase 3Active Not RecruitingPrimary

A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy

NCT05028725Not ApplicableRecruitingPrimary

Novel Strategy for Early Detection of Esophageal Squamous Cell Carcinoma

NCT07090499Phase 1Recruiting

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

NCT05208762Phase 1Recruiting

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

NCT07554521Phase 2Recruiting

A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States

NCT05799274Phase 1Recruiting

Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors

NCT05078047Phase 3Active Not Recruiting

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

NCT07686926Phase 2Not Yet RecruitingPrimary

Becotatug Vedotin Plus Tislelizumab and Low-Dose Lenvatinib for Advanced Esophageal Squamous Cell Carcinoma, Phase II

NCT06047379Phase 1Recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

NCT07554456Phase 2RecruitingPrimary

A Study of BL-B01D1 in Combination With Tislelizumab ±5-Fluorouracil Versus Platinum-Based Chemotherapy Plus Tislelizumab as First-line Treatment in Patients With Unresectable, Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma(PANKU-Esophagus02)

NCT07700667Phase 2Not Yet RecruitingPrimary

SKB500 Combinations in Patients With Esophageal Squamous Cell Carcinoma

NCT06490003RecruitingPrimary

Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma

NCT07699185Phase 2RecruitingPrimary

Neoadjuvant Cardonilizumab Combined With Neoadjuvant Chemoradiotherapy Can Resect Locally Advanced Esophageal Squamous Cell Carcinoma

NCT07697040Phase 1Not Yet RecruitingPrimary

Becotatug Vedotin Plus Cisplatin and Radiotherapy in LA-ESCC

NCT07403136Phase 2RecruitingPrimary

Becotatug Vedotin ± Anti-PD-1 in Pretreated Advanced ESCC

NCT06165380Phase 2Active Not RecruitingPrimary

Cardenilimab Combined With Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

NCT06780111Phase 1RecruitingPrimary

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

NCT04389632Phase 1Recruiting

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

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