RESECTED LYMPH NODES AND SURVIVAL OF PATIENTS WITH ESOPHAGEAL SQUAMOUS CELL CARCINOMA: AN OBSERVATIONAL STUDY

NCT05570487 | Unknown

• 1 other identifier: SichuanCHRIA
• Study Type: observational
• Target: 1,600
• Locations: 1 country
• Sites: 1

Brief Summary

To clarify the effect of the number of lymph node dissection and the number of stations on survival

Conditions

the Records of Esophageal Cancer

Keywords

esophageal cancer; lympha nodes

Outcome Measures

Primary Outcomes (1)

• The number of lymph nodes

  Surgical data were retrospectively collected

  2010.1.1-2017.12.30

Study Arms (4)

N0A Group

patients with negative lymph nodes and resected lymph nodes less than 15

Diagnostic Test: Since the data were collected retrospectively, there were no interventions

N0B Group

patients with negative lymph nodes and resected lymph nodes no less than 15

Diagnostic Test: Since the data were collected retrospectively, there were no interventions

N+A Group

patients with positive lymph nodes and resected lymph nodes less than 15

Diagnostic Test: Since the data were collected retrospectively, there were no interventions

N+B Group

patients with positive lymph nodes and resected lymph nodes no less than 15

Diagnostic Test: Since the data were collected retrospectively, there were no interventions

Interventions

Since the data were collected retrospectively, there were no interventions DIAGNOSTIC_TEST

Since the data were collected retrospectively, there were no interventions

N+A Group; N+B Group; N0A Group; N0B Group

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with esophageal cancer and need surgical treatment.

You may qualify if:

• Men and women aged 18-85;
• Histologically confirmed primary thoracic esophageal squamous cell carcinoma,
• Staging PT1-4A, N0-3, M0 AJCC eighth edition;
• Excluding lymph node dissection \< 15,(meeting the guideline criteria)

You may not qualify if:

• Patients with a history of previous thoracic and abdominal surgery that may affect lymphatic reflux
• Patients with distant metastasis confirmed by imaging;
• Patients with obvious surgical contraindications.

Sponsors & Collaborators

• Yongtao Han: lead

Study Sites (1)

Sichuan Cancer Hospital

Chengdu, Sichuan, 610041, China

RECRUITING

Related Publications (2)

• Li K, Leng X, Peng L. Resected lymph nodes and survival of patients with esophageal squamous cell carcinoma in pT2 and pT3. Int J Surg. 2024 Mar 1;110(3):1879-1881. doi: 10.1097/JS9.0000000000001023. No abstract available.

  PMID: 38116658 DERIVED

• Li K, Leng X, He W, Du K, Li C, Liu K, Wang C, Liu G, Li Z, Jiang L, Li K, Zhou Q, Li J, Luo X, Nie X, Lu S, Li H, Fang Q, Xiao W, Han Y, Peng L. Resected lymph nodes and survival of patients with esophageal squamous cell carcinoma: an observational study. Int J Surg. 2023 Jul 1;109(7):2001-2009. doi: 10.1097/JS9.0000000000000436.

  PMID: 37222685 DERIVED

MeSH Terms

Conditions

Esophageal Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Head and Neck Neoplasms; Digestive System Diseases; Esophageal Diseases; Gastrointestinal Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Clinical Professor

Study Record Dates

• First Submitted: October 4, 2022
• First Posted: October 6, 2022
• Study Start: October 1, 2022
• Primary Completion: December 1, 2022
• Study Completion: October 1, 2023
• Last Updated: October 25, 2022

Record last verified: 2022-10

Locations

CN (1)